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The Hereditary Ontology for Phenoclinical Data

This version:
https://w3id.org/hereditary/ontology/phenoclinical/
Latest version:
https://w3id.org/hereditary/ontology/phenoclinical/
Ontology Version IRI:
https://w3id.org/hereditary/ontology/phenoclinical/1.0/
Revision:
1.0
Authors:
Laura Menotti
Gianmaria Silvello
Download serialization:
RDF/XML TTL
License:
https://creativecommons.org/licenses/by-sa/4.0/
Cite as:
Laura Menotti, Gianmaria Silvello. The Hereditary Ontology for Phenoclinical Data. Revision: 1.0. Retrieved from: https://w3id.org/hereditary/ontology/phenoclinical/schema/1.0/
Ontology Specification Draft

Introduction back to ToC

The Clinical Data Modeling is based on the BrainTeaser Ontology (BTO) [Faggioli et al., 2024]. We followed the same event-based structure but added some properties and classes to include useful information to our use case. In particular, we added a class to represent the affiliated Socio-Health Local Authority (ULSS in Italy) for each patient, one for risk factors, and some properties for MS relapses. The biggest changes are in the Diagnostic Procedure area, where we included several new tests both for ALS and MS patients. Figure 1 reports the schema of the Clinical Data Modeling. The clinical course of ALS and MS patients is organized into eight semantic areas, each denoting a set of ontological classes: “Patient" with “Environmental Data", “Event", “Activity", “Contingencies", and “Intervention or Procedures", divided into “Surgical Procedures", “Diagnostic Procedures", and “Therapeutic Procedures".
HEREDIATRY Ontology for Clinical Data
Figure 1.. The Clinical Data Modeling in HERO-Clinical. The clinical course of ALS and MS patients is organized into eight semantic areas, each denoting a set of ontological classes: ``Patient" (in purple) with ``Environmental Data" (in brown), ``Event" (in blue), ``Activity" (in green), ``Contingencies" (in yellow), and ``Intervention or Procedures" (in pink), comprising ``Surgical Procedures" (in pink), ``Diagnostic Procedures" (in pink), and ``Therapeutic Procedures"(in orange).

Namespace declarations

Table 1: Namespaces used in the document
Pollution<http://ontology.eil.utoronto.ca/GCI/Environment/Pollution.owl#>
UATC<http://purl.bioontology.org/ontology/UATC/>
[Ontology NS Prefix]<https://w3id.org/hereditary/ontology/phenoclinical/schema/>
adms<http://www.w3.org/ns/adms#>
contact<http://www.w3.org/2000/10/swap/pim/contact#>
dc<http://purl.org/dc/elements/1.1/>
foaf<http://xmlns.com/foaf/0.1/>
isco<http://data.europa.eu/esco/isco/>
ns<http://creativecommons.org/ns#>
obo<http://purl.obolibrary.org/obo/>
om-1<http://www.wurvoc.org/vocabularies/om-1.8/>
orcid<https://orcid.org/0000-0002-0676-682>
owl<http://www.w3.org/2002/07/owl#>
rdf<http://www.w3.org/1999/02/22-rdf-syntax-ns#>
rdfs<http://www.w3.org/2000/01/rdf-schema#>
schema<https://w3id.org/brainteaser/ontology/schema/>
skos<http://www.w3.org/2004/02/skos/core#>
ssn<http://purl.oclc.org/NET/ssnx/ssn#>
terms<http://purl.org/dc/terms/>
time<http://www.w3.org/2006/time#>
vann<http://purl.org/vocab/vann/>
xml<http://www.w3.org/XML/1998/namespace>
xsd<http://www.w3.org/2001/XMLSchema#>

Overview back to ToC

This ontology has the following classes and properties.

Classes

Object Properties

Data Properties

Named Individuals

Methodology back to ToC

Design Principles

In the following, we report how HERO has been designed to meet the Open Biological and Biomedical Ontology Foundry (OBO) and FAIR principles also favoring its adoption in heterogeneous scenarios. The detailed description of each of the OBO principle is available at https://obofoundry.org/principles/fp-000-summary. html.
  • First, the ontology is Open and publicly available. It is possible to find its definition and description at http://hereditary.dei.unipd.it/ontology/phenoclincal/.
  • Secondly, the ontology schema is defined according to the OWL 1.2 Common Format
  • The proposed ontology relies on a unique URI/Identifier Space identified by the prefix https://w3id.org/hereditary/ontology/phenoclincial/schema/.
  • A description of the Versioning procedure is available as part of the documentation of HERO.
  • The Scope of HERO is clearly defined: the ontology is meant to model the anamnestic and clinical history of patients affected by two neurological diseases, ALS and MS.
  • Following the OBO principles, we associate Textual Definitions to each class of the ontology, to also favour its re-usage in other scenarios.
  • Before defining a new relation, Relations available on the Relations Ontology (RO) have been accurately considered. None of the HERO relations presents the same meaning and could have been replaced with one of the RO – nevertheless, this possibility has been always attentively scrutinized.
  • A detailed Documentation of the ontology is available on its web page.
  • For what concerns Documented Plurality of Users and Commitment To Collaboration, these aspects are intrinsic in the development and usage of the HERO ontology. In fact, HERO has been developed in the context of the HEREDITARY Project, which includes partners from multiple European countries. The co-design approach used to devise HERO defines its collaborative nature.
  • HERO clearly identifies its Locus of Authority into its developers, who are indicated on the web page of the ontology.
  • HERO follows strict Naming Conventions described below.
  • Finally, the HEREDITARY consortium is actively working on the Maintenance and update of HERO.

Co-design Approach

To design the HERO, we adopted a co-design approach, strictly collaborating with the medical partners and domain experts, in order to embed their knowledge in the HERO and, at the same time, to validate all the design choices. To this end, we operated in an iterative way, producing several intermediate versions of the ontology, and discussing them with our domain experts. We exploited the iterative process of discussion with the medical partners to make sure that these newly defined concepts correctly described the corresponding real-world concepts and to guarantee the semantic quality of the ontology.

Implementation Principles

To provide consistency in HERO we expressed some basic principles to adopt when defining classes and properties. These guidelines involve external referencing, anno- tation properties, and naming conventions.

External Referencing Whenever we model clinical information, it is preferable to use external ontologies to provide correspondence between largely used medical terminology. Due to its widely diffused adoption and exhaustiveness, our primary taxonomy of choice is NCIT [30], but we also employed other well-known resources when no information is available in NCIT, e.g. SNOMED-CT or ATC. In general, this is common practice when developing ontologies [44]. In fact, by reusing entities and properties already defined in other ontologies, we are not only able to enforce collaboration and data consistency among databases but to guarantee the authori- tativeness of the semantic meaning of these resources. External referencing has been managed with annotation properties and using the URI of the term in the original taxonomy. In general, we used external URIs when we defined named individuals that refer to abstract concepts. On the contrary, when we inserted a new class in HERO we used the Hereditary namespace and connected references using annotation properties.

Namespaces HERO URIs are divided into two namespaces: the schema namespace https://w3id.org/hereditary/ontology/schema/ and the resource namespace https://w3id.org/hereditary/ontology/resource/. All URIs corresponding to classes, data properties, and object properties belong to the former namespace. At the same time, in the latter, we include all URIs referring to real-world instances of the entities described in HERO at an ontological level. Notice that, in this sense, the resource namespace is empty until the practitioner starts populating it with real-world data. The only instances included in the schema namespace are the named individuals corresponding to Simple Knowledge Organization System (SKOS) concepts (as defined in Subsection 3.4). Our choice of including these elements in the schema namespace stems from the fact that, akin to relational modeling controlled dictionaries, these entities do not depend on the data underneath but can be seen as a predefined thesaurus of concepts and are a fundamental part of the environment that we model.

Classes Definition and Annotation Properties All components of the HERO have additional information in the form of annotation properties. We defined a list of essential metadata to add when we introduced a new class. Firstly, all classes must have a label denoting the name and a comment, which provides a brief explana- tion together with its source. If the class had an equivalent in NCIT, we inherited the name and definition. In this case, we also added another annotation property called “rdfs:isDefinedBy with the Internationalized Resource Identifier (IRI) corre- sponding to the NCIT term of reference. Most biomedical vocabularies are mapped in the UMLS with a unique identifier called Concept Unique Identifier (CUI) [40]. For each class that had a UMLS reference, we added the annotation property “dcterms:conformsTo” with the URL of the corresponding concept.

Naming Conventions Regarding object and data properties, we applied a similar approach and defined the needed annotations and naming conventions to provide uniformity throughout HERO. In particular, all components must have a label and a comment. About object properties, we used explanatory labels where we included the property range. In this case, the comment explains the relationship between the two classes involved. Concerning data properties, the label usually includes the name of the domain class so that its meaning is intuitive. We also added a comment with the attribute description and, when available, the definition source. In conclusion, we defined all data properties to achieve consistency when specifying datatypes. For example, all string properties have datatype “rdf:PlainLiteral”. We also used the “note” annotation property in all HERO components for additional remarks or business logic rules.

Usage of the Simple Knowledge Organization System (SKOS)

In ontology design, it is good practice to use external taxonomies [44] – which are not necessarily ontologies – to ensure correspondence with the most common terminology, especially in the medical domain. This is common practice when developing ontologies, in fact by reusing entities and properties already defined in other ontologies, we are not only able to enforce the collaboration and data consistency among database, but to guarantee the authoritativeness of the semantic meaning of these resources. In HERO, external resources have been employed for example to model the diseases affecting a patient, anatomical sites of traumas, and pharmacological substances. The common aspect between these elements is that we are interested in the abstract concept behind the medical term. To avoid classism – the design pattern where an external hierarchy is modeled as a hierarchy of ontological classes – whenever we modeled a classification scheme that used an external taxonomy we employed the SKOS data model. Each component of the referenced ontology has been modeled as a named individual that belongs to two classes, SKOS Concept and the one in HERO. This has two important advantages: i) it allows to save space, by dramatically reducing the number of needed URI ii) it reduces the complexity of the queries. The disadvantage of this approach is that it prevents us from describing the peculiarities of the specific head of the specific patient. Nevertheless, since it is not a requirement of our ontology, we opted for the modeling pattern described above. We employed such a design principle for each class that refers to a set of abstract terms and does not have any data or object property associated. All classes modeled using the SKOS standard and the corresponding taxonomy of reference are reported in the table below.
List of classes in the Hereidtary Ontology modeled using the SKOS data model. For each class we specify its name and the reference taxonomy we use to define the concepts.
ClassReference Taxonomy
Kinship TypeNational Cancer Institute Thesaurus (NCIT)
OccupationOccupations pillar of the ESCO Classification (ESCO)
Group (social concept)SNOMED Clinical Terms (SNOMED-CT)
GeneNational Cancer Institute Thesaurus (NCIT)
Disease, Disorder or FindingsNational Cancer Institute Thesaurus (NCIT)
Surgical Procedure TypeSNOMED Clinical Terms (SNOMED-CT)
Therapeutic Procedure TypeNational Cancer Institute Thesaurus (NCIT)
Anatomic SiteNational Cancer Institute Thesaurus (NCIT)
Pharmacological SubstanceAnatomical Therapeutic Chemical (ATC) Classification
Advesre Drug ReactionOntology of Adverse Events (OAE)
As the main reference thesaurus, we employed NCIT whenever it contained any needed concepts and we used other well-known resources otherwise. We defined new concepts within HERO namespace only if they referred to terms specific to our domain of interest and the corresponding concept was not available anywhere else. To provide a more practical example, assume the practitioner needs to model the fact that a patient suffered from head trauma. We do not need to refer – and thus define a URI for it – to the head of the specific patient, but we only need to associate the individual “trauma” for the patient with a generic individual representing the entity “head”. Notice that, we are forced to instantiate the specific patient’s trauma and assign it a URI: the patient’s trauma has some attributes (such as a date) and might have happened in other places besides the head. Therefore, for all patients affected by head trauma, we create an URI for the specific patient’s trauma, and we link it with the object property “bo:trauma” to the URI of the generic concept of “head” – the same for all head traumas. The concept “head” is defined in HERO with a NCIT URI.

Description back to ToC

The Hereditary ontology models clinical and genomics data to provide a unifying layer to query different database sources through an Ontology-Based Data Access (OBDA) framework. This part of the ontology focuses on phenoclinical data for ALS and MS patients. . The Clinical Data Modeling is based on the BrainTeaser Ontology (BTO) [Faggioli et al., 2024]. We followed the same event-based structure but added some properties and classes to include useful information to our use case. In particular, we added a class to represent the affiliated Socio-Health Local Authority (ULSS in Italy) for each patient, one for risk factors, and some properties for MS relapses. The biggest changes are in the Diagnostic Procedure area, where we included several new tests both for ALS and MS patients.

Patient Modeling

BTO is a tool to model each person’s disease progression, with the objective of helping understand its progression. To better contextualize the patient’s clinical history, several pieces of information need to be recorded. In particular, BTO focuses on data about each patient’s lifestyle, clinical events, and clinical family history. Such information is modeled in the “Patient” semantic area, as illustrated in Figure 2.
BRAINTEASER: patient area

Figure 2: Patient semantic area. “Patient” is a subclass of the class Person from FOAF ontology. We directly connect to patient data about genetic mutations, occupation, family history, and residence place. The latter is useful to link environmental information to each patient, which is modeled by importing the “Global City Indicator Environment Ontology” [38].

Patients’ data requirements are equivalent for those affected by MS and ALS. In both cases, Clinicians might need to record personal information, like age and gender, together with clinical family history and possible participation in clinical trials. For each patient, pieces of information about their relatives can be retrieved by using the class “Kinship” which connects patients and relatives with the object properties “:hasKinship” and “:inKinshipWith” respectively. For instance, if we are interested in identifying all patients that have a relative affected by ALS, we look for individuals of type “Patient” that are connected to nodes of type “Kinship”. If the relative participating in this relation has object property “:hasDisease” with range “ALS”, then the patient is retrieved. In this case, the individual “ALS” is a SKOS concept of type “Disease, Disorder or Finding” with IRI from NCIT. In addition, the practitioner might want to store data about whether a patient’s genome presents specific gene mutations linked to the ALS disease. To encompass this, we modeled such information on the “Genetic Data” area. To extract which patients have a gene mutation, we look for each individual of type “Patient” that has object property “:tested” and the range node has data property “:hasMutation” set to “True”. Now, if we also want to return the gene that presented the mutation we connect the already extracted individual of type “Genetic Testing” with the gene using the object property “:onGene”.

Environmental Data

Besides genetic predisposition, lifestyle and environmental factors are shown to affect the risk of MS. Once we acknowledge such correlation, some of these environmental and lifestyle factors can be modified with prevention measures, especially for people at greater risk [45]. On the other hand, identifying environmental factors linked to ALS has proven to be challenging and it still lacks large cohorts. In both cases, understanding the interaction between genetic and environmental factors can be a great resource for integrating precision medicine into ALS or MS care [46]. That is why connecting environmental data to each patient in BTO is a fundamental requirement. These environmental data include pollution information for a given location, recorded by a weather station. To store this piece of information, in BTO the practitioner can record each patient’s birth and residence places using the class “Place”. To model environmental data, we imported Global City Indicator Environment Ontology[38], also known as Pollution ontology, an ontology designed to represent ontologically environmental data registered by weather stations. In par- ticular, we connected a weather station, modeled with the class “Sensing Device” from the above-mentioned ontology, to a location, modeled with the class “Place”, with the object property “:coveredPlace”, to model the fact that a station registers environmental data for a given location. We report how we integrated air pollutants in Figure 3. The concentration of each air pollutant of interest is modeled as a subclass of “Air Pollution Concentration”. Notice that we are interested in storing information about Particulate Matter (PM) 10, PM 2.5, Ozone (O3), Nitrogen Dioxide (NO2), Sulphur Dioxide (SO2), and Carbon Monoxide (CO) thus we created a class in our namespace for pollutants not represented in the imported ontology, such as CO. Air pollution concentrations are produced by sensing de- vices, thus we connected the classes “Air Pollution Concentration” and “Sensing Device” with the property “ssn:isProducedBy”. The concentration value of each air pollutant is stored using the data property “numerical value”, while the date of the measure is referred to with the object property ":APConcentrationTIme" that links “Air Pollution Concentration” class to class “time:Instant”. All classes, object properties, and data properties mentioned above are imported from the “Global City Indicator Environment Ontology”[38].

BRAINTEASER: environmental area

Figure 3: Environmental data integration using the imported “Global City Indicator Environment Ontology” [38]. We linked the class “Place” with “Sensing Device”, which produces pollution concentration data. Such information is stored using one of the subclasses of “Air Pollution Concentration”, which represents the specific pollutant.

Event Modeling

The clinical history of a patient is not directly connected to the “Patient” class itself, but we assume such data to be registered during a clinical visit where, for instance, the physician fills a form with patient information regarding any relevant clinical event, physical activities, habits, or any arisen clinical condition communicated by the patient to the clinician during the visit. For this reason, we modeled the “Event” semantic area as follows. We specified four subclasses of the class “Event”, each with its specific data prop- erties. The possible event types are: i) the “Before Onset” event, describing as a cumulative event, everything that happened before the onset of the symptoms and for which there are no specific temporal details; ii) the “Onset”, describing the event when a patient experimented the symptoms for the first time; iii) the Diagnosis event, describing the event and exams carried out when the patient was diagnosed with the disease; iv) a “Protocol Event”, representing any possible occurrence happened after the diagnosis. A visual depiction of the modeling approach is reported in Figure 4.
BRAINTEASER: event area

Figure 4: Event semantic area. Each patient is connected to clinical history and lifestyle information through the class Event. In fact, using such nodes physicians can store data about habits, past traumas, any clinical event (class “Condition”), coexisting medical conditions (called “comorbidities”), or pregnancies and MS patients’ relapses.

In BTO, practitioners can model information about physical activities, smoking habits, and other lifestyle information concerning the patient, by instantiating an individual of type “Activity” or any of its subclasses: “Physical Activity”, “Smoking”, and “Lifestyle”. For instance, assume the practitioner needs to model the fact that, during a check-up, the patient shared information about smoking 10 cigarettes a day. A new individual of type “Protocol Event” is instantiated to record all the details about the check-up. After that, an individual of type “Smoking” is instantiated and is connected to the event related to the checkup with object property “:hasRegisteredActivity”. Then the frequency information is stored using the data property “:dailyCigarettes” of the smoking node just created. Additional information, such as tests carried out or prescriptions provided during the check-up, will be linked to the “Protocol Event” instance defined above. Regarding clinical history, during an event, the clinician can register past traumas, coexisting medical conditions, pregnancies, and relapses – in the case of MS patients. These pieces of information constitute the “Contingencies” area, where the class “Condition” is linked to “Disease, Disorder or Finding” by the object property “:hasRegisteredCondition”. For instance, if the clinician wants to model the fact that a patient had the flu, they instantiate an individual of type “Condition” and add a triple stating that, during the considered event, a condition determined by the disease “Flu” was recorded.

Disease, Disorder or Finding Taxonomy

The class “Disease, Disorder or Finding” includes diseases, like carcinoma or chickenpox infection, but also injuries, symptoms, and findings. This allows modeling and storing in a KB any sort of clinical event that occurred to a patient, even if it is not directly linked to ALS or MS. We modeled this class following the SKOS data model, using NCIT as reference taxonomy, with a few additions from SNOMED-CT thesaurus. As illustrated in Figure 4, we modeled past traumas with the class “Trauma”. However, some injuries have also been made available in the “Disease, Disorder or Finding” taxonomy. As a general rule, we use the taxonomy whenever the trauma is specific (e.g., “Open Dislocation of the Shoulder”). On the other hand, if the clinician knows only that a patient suffered from generic trauma to the shoulder, we instantiate an individual of type “Trauma” and connect it to its Anatomic Site (e.g., “shoulder”) with the property “:anatomicalLocation”. Notice that, thanks to SKOS characteristics, specific traumas (e.g., “open dislocation of the shoulder”) are in relation “:hasBroaderTransitive” with the general concept “injury”. We follow a similar line of thought to deal with symptoms. In this case, we use the taxonomy to model cases where the practitioner needs to store information about general symptoms (e.g., headache, fever). A particular group of symptoms that required deeper modeling granularity is the one that constitutes the onset of the disease (either ALS or MS). Given the high relevance that such symptoms have on the course of the disease, they have not been modeled using the symptoms taxonomy but as data properties of the class “Onset”.

Intervention Modeling

According to the proposed modeling paradigm, an event might include one or more interventions – for example, a visit might include multiple exams and multiple pre- scriptions of therapeutic substances. Therefore the “Intervention or Procedures” semantic area comprises surgical procedures, diagnostic tests, and therapeutic treat- ments. Figure 5 illustrates the main classes and properties involved in this semantic area. “Intervention or procedure” has three subclasses – “Surgical Procedure”, “Diagnostic Procedure” and “Therapeutic Procedure” – each denoting different operations.
BRAINTEASER: intervention area

Figure 5: “Intervention or Procedures” area. We distinguish between surgical procedures, diagnostic procedures, and therapeutic procedures. Both surgical and therapeutic interventions are the same for MS and ALS patients while diagnostic procedures can differ based on the disease.

"Surgical Procedures” includes all treatments that involve surgery. Since different surgery procedures might vary widely, in BTO we define the class “Surgery Procedure Type” to represent different surgery types. This class is modeled following the SKOS standard and using the SNOMED-CT taxonomy as a reference. Furthermore, we linked the “Surgical Procedure” class to “Anatomic Site” to allow clinicians to store information about which body region was affected by the surgery. In this way, one can both instantiate the surgery type or the anatomical location based on the information available or the need of the developed application.

Diagnostic procedures differ based on MS or ALS patients. For instance, MS patients can take an Evoked Potentials test or a CSF analysis and their level of disability can be monitored over time using the EDSS. On the contrary, ALS patients are tested on their pulmonary function and the disease progression can be assessed using the Revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R), the King’s clinical staging method (KINGS), or the Milano-Torino functional staging system (MiToS). Diagnostic intervention information can be a great reason for assessing the disease progression of each patient. For example, with BTO we can return the number of patients having an EDSS score in between some ranges, which can be an indicator of impairment severity in patients affected by MS. One peculiarity is that hematology test components have been modeled as a class called “Laboratory Test Result” where the clinician can specify the component name, the measured level, its unit of measure, and whether the result was normal. We also included a data property called “:positivyResult” to express the presence or absence of specific blood components (e.g., antibodies).

Figure 6 reports the diagnostic procedure semantic area modeled in HERO. We highlighted with different colors the novel components added to HERO compared to BTO. We added some properties to classes “CSF Analysis" and “Clinical Evaluation" to include walking status assessments and additional CSF method information. Concerning ALS patients, we added six new classes, two representing neurological exam and blood gas analysis, while the others represent the assessment of muscle response to nerve stim- ulation. On the other hand, MS novel exams include cognitive assessment tests and three questionnaires, two of which are self-reported by patients. The “Cognitive Assessment" class includes exams to assess le- sions distribution, e.g. “Corpus Callosum Topography Score (CLTR)" and “Lesion Topography Score (LTS)", and tests for cognitive functions, e.g. “Symbol Digit Modalities Test (SDMT)" and “Paced Auditory Serial Addition Test (PASAT)". The questionnaires include the “Multiple Sclerosis Neuropsychological Question- naire (MSNQ)", “Fatigue Severity Score" (self-reported), and “Beck Depression Inventory-II (BDI-II)" (self- reported).

HERO-Clinical: diagnostic procedures area

Figure 6: The Diagnostic Procedure area in HERO-Clinical. The components highlighted in orange and pink are novel diagnostic procedures or properties for MS and ALS patients respectively, included in HERO.

We identified a specific semantic field for “Therapeutic Procedures” which comprises any treatment and the administration of any pharmacologic substance. In a single therapeutic treatment, the clinician could administrate multiple phar- macologic substances in different time periods. For this reason, we modeled this area by introducing the class “Therapeutic Treatment”, which is the core of the semantic area as illustrated by Figure 7 .

BRAINTEASER: therapeutic procedures area

Figure 7: “Therapeutic Procedures” area. The core of the area is the “Therapeutic Treatment” class, where one can store information about drug administrations and its specific aspects, such as dose, frequency and end treatment. In particular, we modeled the “End Therapy Reason” as a class so that we can link possible causes, such as adverse events and pregnancy.

With this class, we modeled both drug administrations and other therapeutic treatments like Non-Invasive mechanical Ven- tilation (NIV). We used the class “Therapeutic Procedure Type” to specify the pharmacologic substance category or the type of therapy, if not pharmacological. For instance, if clinicians want to record information about a patient requiring NIV one can create a new node of type “Therapeutic Treatment” with object property “:therapyType” and range “NIV”. With this model, practitioners can store information about the administration specifics like dose and frequency and they can also insert data about the reason for the interruption of treatment. In such case, we connected the class “End Therapy Treatment” to the class “Adverse Drug Reaction” and “Pregnancy”. Concerning Therapeutic treatments, we modeled as SKOS hierarchies Adverse Drug reactions using OAE Ontology, Pharmacological Substances using the ATC Ontology, and the Therapeutic Procedure Types, relying on NCIT.

Cross-reference for classes, object properties and data properties back to ToC

This section provides details for each class and property defined by The Hereditary Ontology for Phenoclinical Data.

Classes

Activityc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Activity

An active process; excludes processes and mechanisms which fulfill biological functions. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C43431
has sub-classes
Lifestyle c, Physical Activity c, Risk Factor c, Smoking c
is in domain of
acitivityStartYear dp, activityEndYear dp
is in range of
hasRegisteredActivity op

Administrationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Administration

The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25409
is in domain of
administrationDose dp, administrationFrequency dp, administrationRoute dp, administrationUoM dp
is in range of
administration op

Adverse Drug Reactionc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/AdverseDrugReaction

Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C142385
is in range of
adverseReaction op
has members
Administration of Ineffective Drug ni, Adverse Drug Event ni, Drug Hypersensitivity AE ni, Drug Intolerance AE ni

ALS Brainteaser Comorbiditiesc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ALSBrainteaserComorbidities

Comorbidities checked for ALS patient in the BRAINTEASER study.
has super-classes
Use-Case Comorbidities c
is in domain of
autoimmuneDisease dp, cardiacDisease dp, diabetes dp, dyslipidemia dp, hypertension dp, primaryNeoplasm dp, stroke dp, thyroidDisorder dp

Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ALSFRS

The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is an instrument for evaluating the functional status of patients with Amyotrophic Lateral Sclerosis. It can be used to monitor functional change in a patient over time. [Definition Source: Georgetown University Hospital - Medstar Health]
has super-classes
Questionnaire c
is in domain of
alsfrs1 dp, alsfrs10 dp, alsfrs11 dp, alsfrs12 dp, alsfrs2 dp, alsfrs3 dp, alsfrs4 dp, alsfrs5 dp, alsfrs6 dp, alsfrs7 dp, alsfrs8 dp, alsfrs9 dp, alsfrsOriginal10 dp, bulbarSubscore dp, motorSubscore dp, originalALSFRS dp, respiratorySubscore dp, revisedALSFRS dp

Anatomic Sitec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/AnatomicalSite

Named locations of or within the body. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C13717
is in range of
anatomicalLocation op
has members
Abdomen ni, Bone Marrow ni, Brain ni, Brain Stem ni, Cerebellum ni, Cervical Spinal Cord ni, Cervical Spine ni, Eye ni, Head ni, Limb ni, Lower Extremity ni, Lumbar Spine ni, Lumbosacral Region ni, Neck ni, Pelvis ni, Sphincter ni, Spinal Cord ni, Supratentorial Brain ni, Thoracic Spinal Cord ni, Thoracic Spine ni, Thorax ni, Upper Extremity ni, Vertebral Column ni

Beck Depression Inventory-II (BDI-II)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/BDIII

BDI-II (Beck Depression Inventory-II) is a self-report questionnaire used to assess the severity of depression in multiple sclerosis patients. By analyzing BDI-II scores alongside brain connectivity metrics, researchers can explore how depression severity relates to brain network organization and function in individuals with MS.
has super-classes
Self-Reported Questionnaire c

Before Onsetc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/BeforeOnset

Any event that happened to a patient before the onset.
has super-classes
Event c
has sub-classes
Last 5 Years Event c, More Than 5 Years Event c
is in domain of
hadMajorTrauma dp, hadSurgicalIntervention dp, onsetElapsedTime dp

Blood Gas Analysisc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/BloodGasAnalysis

Measurement of oxygen and carbon dioxide in the blood. [Definition Source: MSH]
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/278297009
has super-classes
Diagnostic Procedure c
is in domain of
bloodGasPCO2 dp, bloodGasPH dp, bloodGasPO2 dp, bloodGasSO2 dp

c6 h6 concentrationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/C6H6_concentration

has super-classes
air pollution concentration c

Clinical Evaluationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ClinicalEvaluation

An assessment of an individual's physical, mental, or emotional condition; information can be gathered from multiple sources, including physical exam, personal interview and observation, medical history, laboratory and imaging tests. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C124351
has super-classes
Diagnostic Procedure c
is in domain of
bodyMassIndex dp, emotionalLiability dp, height dp, massetericReflex dp, moreThan10PercentWeightloss dp, multipleSclerosisType dp, muscleAtrophy dp, muscleTone dp, predominantLimbsImpairment dp, predominantLimbsSide dp, predominantMotorNeuron dp, raoClassification dp, upperLimbsMobility dp, urinaryUrgency dp, urinaryUrgencyTherapy dp, walkEvaluation dp, weight dp

Clinical Trialc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ClinicalTrial

A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C71104
is in domain of
clinicalTrialDescription dp, conductedInClinic op, isAboutDisease op
is in range of
inClinicalTrial op

Clinical Trial Participationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ClinicalTrialParticipation

The participation in a clinical trial
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/709491003
is in domain of
endReason dp, inClinicalTrial op, participationEnd dp, participationStart dp
is in range of
enrolledIn op

Clinics and Hospitalsc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ClinicsAndHospitals

Institutions with an organized medical staff for the medical care, treatment, and cure of the sick and wounded, for the study of disease, and for the training of physicians, nurses, and allied health personnel. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C19326
is in range of
conductedInClinic op
has members
Hospital General Universitario Gregorio Marañón ni, Institute of Molecular Medicine Joao Lobo Antunes ni, Mondino Foundation ni, University of Padua ni, University of Turin ni

CO concentrationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/CO_concentration

The determination of the amount of carbon monoxide present in a sample. [Definition Source: NCI]
has super-classes
air pollution concentration c

Cognitive Assessmentc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/CognitiveAssessment

The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C62736
has super-classes
Diagnostic Procedure c
has sub-classes
Corpus Callosum Topography Score (CLTR) c, Delis-Kaplan Executive Function System (D-KEFS) c, Lesion Topography Score (LTS) c, Paced Auditory Serial Addition Test (PASAT) c, Selective Reminding Test - Delayed c, Spatial Recall Test (SPART) c, Symbol Digit Modalities Test (SDMT) c, Symbol Digit Modalities Test - Delayed (SPART-D) c, Word List Generation (WLG) c
is in domain of
betweenessCentralityCoefficient dp, clusteringCoefficient dp, globalCoefficient dp

Comorbidityc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Comorbidity

The coexistence of two or more disease processes. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16457
has super-classes
Conditon c
has sub-classes
Use-Case Comorbidities c
is in domain of
comorbiditySeverity dp, comorbidityTreatment dp, determinedBy op

Company-Socio-Health Local Autorityc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/AULSS

The Local Health Autority denomination in Veneto.
has super-classes
Local Health Autority c

Conditonc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Condition

A state of being, such as a state of health. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25457
has sub-classes
Comorbidity c, Impairment c
is in domain of
conditionEnd dp, conditionStart dp
is in range of
hasRegisteredCondition op

Corpus Callosum Topography Score (CLTR)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/CLTR

CLTR (Corpus Callosum Topography Score) quantifies lesion load and distribution within the corpus callosum of multiple sclerosis patients. By analyzing CLTR alongside brain connectivity metrics, researchers can assess how callosal damage affects inter-hemispheric communication efficiency and its impact on cognitive function.
has super-classes
Cognitive Assessment c

CSF Analysisc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/CSFAnalysis

A laboratory analysis of a sample of cerebrospinal fluid. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C173272
has super-classes
Diagnostic Procedure c
is in domain of
IgGIndexCSF dp, albuminCSF dp, alterationCSF dp, glucoseCSF dp, granulocytesCSF dp, immunoglobulinGCSF dp, leukocytesCountCSF dp, lymphocytesCSF dp, methodCSF dp, pathologicalJCCSF dp, performedCSF dp, performedCSFAnalysis dp, proteinsCSF dp, quotientAlbuminCSF dp, testedForOligoclonalBands op, virusJCTestedCSF dp

Delis-Kaplan Executive Function System (D-KEFS)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/DKEFS

The Delis–Kaplan Executive Function System (D-KEFS) is a neuropsychological test used to measure a variety of verbal and nonverbal executive functions for both children and adults (ages 8–89 years). [Definition Source: Wikipedia]
has super-classes
Cognitive Assessment c
has sub-classes
Delis-Kaplan Executive Function System Color-Word Interference Switching Condition (D-KEFS FSC) c, Delis-Kaplan Executive Function System Design Fluency Condition (D-KEFS FSD) c, Delis-Kaplan Executive Function System Sorting Test - Free Sort & Sort Recognition (D-KEFS SR) c
is in domain of
formatDKEFS dp

Delis-Kaplan Executive Function System Color-Word Interference Switching Condition (D-KEFS FSC)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/DKEFSFSC

D-KEFS FSC (Delis-Kaplan Executive Function System Color-Word Interference Switching Condition) assesses cognitive flexibility and switching ability in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics researchers can identify how MS affects brain networks involved in executive function and task switching.
has super-classes
Delis-Kaplan Executive Function System (D-KEFS) c

Delis-Kaplan Executive Function System Design Fluency Condition (D-KEFS FSD)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/DKEFSFSD

D-KEFS FSD (Delis-Kaplan Executive Function System Design Fluency Condition) assesses creativity and the ability to generate novel ideas in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics, researchers can identify how MS affects brain networks involved in creative thinking and fluency.
has super-classes
Delis-Kaplan Executive Function System (D-KEFS) c

Delis-Kaplan Executive Function System Sorting Test - Free Sort & Sort Recognition (D-KEFS SR)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/DKEFSSR

D-KEFS SR (Delis-Kaplan Executive Function System Sorting Test - Free Sort & Sort Recognition) assesses problem-solving, abstract thinking, and cognitive flexibility in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics, researchers can identify how MS affects brain networks involved in these cognitive processes.
has super-classes
Delis-Kaplan Executive Function System (D-KEFS) c

Diagnosisc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Diagnosis

The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C15220
has super-classes
Event c
is in domain of
diagnosticCriteria dp, msDiagnosis2010Criteria dp

Diagnostic Imagingc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DiagnosticImaging

Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16502
has super-classes
Diagnostic Procedure c
has sub-classes
Magnetic Resonance Imaging (MRI) c, Positron Emission Tomography (PET) c

Diagnostic Procedurec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DiagnosticProcedure

Any procedure or test to diagnose a disease or disorder. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C18020
has super-classes
Intervention or Procedure c
has sub-classes
Blood Gas Analysis c, CSF Analysis c, Clinical Evaluation c, Cognitive Assessment c, Diagnostic Imaging c, Electromyography c, Evoked Potentials c, Expanded Disability Status Scale (EDSS) c, Hematology Test c, Hoffman's Reflex Test c, Muscle Biopsy c, Neurologic Exam c, Plantar Reflex Test c, Pulmonary Function Test c, Questionnaire c, Tendon Reflex Test c

Disease, Disorder or Findingc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DiseaseDisorderOrFinding

A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C7057
is in range of
determinedBy op, hasDisease op, isAboutDisease op
has members
Abdominal Pain ni, Acquired Hypothyroidism ni, Acute Cystitis ni, Acute Myocardial Infarction ni, Acute Pyelonephritis ni, Acute Respiratory Failure ni, Acute Tonsillitis ni, Adenocarcinoma ni, Ageusia ni, Alanine Aminotransferase Increased ni, Alcohol Dependance ni, Allergic Asthma ni, Allergic Rhinitis ni, Alzheimer's Disease ni, Amenorrhea ni, Amenorrhea due to Pituitary Dysfunction ni, Amyotrophic Lateral Sclerosis ni, Anemia ni, Angioedema ni, Ankle Fracture ni, Ann Arbor Stage IV Mantle Cell Lymphoma ni, Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma ni, Anorectal Fistula ni, Anorexia ni, Anosmia ni, Anxiety Disorder ni, Arrhythmia ni, Arthritis ni, Aspiration Pneumonitis ni, Asthma ni, Atopic Dermatitis ni, Atrial Fibrillation ni, Atrial Flutter ni, Autoimmune Disease ni, Autoimmune Nervous System Disorder ni, Autoimmune Pancytopenia ni, Bacterial Pneumonia ni, Baker Cyst ni, Basal Cell Carcinoma ni, Behavioral Impairment ni, Bell's Palsy ni, Bipolar Disorder ni, Blepharitits ni, Blepharospasm ni, Bowel Obstruction ni, Bradycardia ni, Breast Carcinoma ni, Brown-Sequard Syndrome ni, COVID-19 Infection ni, Carcinoma ni, Cardiovascular Disorder ni, Cavernous Hemangioma ni, Celiac Disease ni, Central Nervous System Degenerative Disorder ni, Chalazion ni, Chicken Pox ni, Chronic Atropic Gastritis ni, Chronic Lung Disorder ni, Cleft Palate ni, Closed Dislocation of Shoulder ni, Closed Fracture of Rib ni, Closed Fracture of Tibia ni, Cognitive Impariment ni, Cold Sore ni, Colon Adenocarcinoma ni, Common Bile Duct Stone ni, Congenital Adrenal Hyperplasia ni, Cranial Nerve VII Palsy ni, Cutaneous Melanoma ni, Cyst ni, Deep Vein Thrombosis ni, Dementia ni, Depression ni, Diabetes Mellitus ni, Diabetic Ketoacidosis ni, Disease or Disorder ni, Dog Bite ni, Drug Hypersensitivity Syndrome ni, Dyslipidemia ni, Eczema ni, Endometriosis ni, Epidermal Inclusion Cyst ni, Essential Hypertension ni, Extrapyramidal Disorder ni, Favism ni, Femur Fracture ni, Fever Chills ni, Fibroma ni, Fibromyalgia ni, Finding ni, Flu-Like Symptoms ni, Frontotemporal Dementia ni, Fungal Infection ni, Gastritis ni, Gastroenteritits ni, Gastroesophageal Reflux ni, Generalized Epilepsy ni, Glaucoma ni, Hashimoto Thyroiditis ni, Head Trauma ni, Head and Neck Finding ni, Headache ni, Heart Failure ni, Hepatic Toxicity ni, Hepatitis ni, Hepatitis A Infection ni, Hereditary Factor XI Deficiency ni, Hereditary Hemolytic Anemia ni, Hernia ni, Herpes Simplex Keratitis ni, Herpes Simplex Virus Infection ni, Herpes Zoster ni, High Grade Cervical Squamous Intraepithelial Neoplasia ni, Hypercholesterolemia ni, Hypersensitivity ni, Hypertension ni, Hypertensive Crisis ni, Hyperthyroidism ni, Hypothyroidism ni, Ichthyosis ni, Infectious Mononucleosis ni, Inguinal Hernia ni, Injury ni, Interstitial Pneumonia ni, Intervertebral Disc Prolapse ni, Intestinal Pseudo-Obstruction ni, Iridocyclitis ni, Iron-Deficiency Anemia ni, Keratitis ni, Keratoconus ni, Klippel-Feil Syndrome ni, Langerhans Cell Histiocytosis ni, Leukopenia ni, Long QT Syndrome ni, Lumbar Hernia ni, Lumbar Puncture Headache ni, Lymphopenia ni, Malignant Colon Neoplasm ni, Malignant Neoplasm ni, Malignant Skin Neoplasm ni, Malignant Thyroid Gland Neoplasm ni, Melanocytic Nevus ni, Migraine ni, Migraine With Aura ni, Molluscum Contagiosum Virus ni, Monoclonal B_Cell Lymphocytosis ni, Monoclonal Gammopathy ni, Mood Disorder ni, Motor Neuron Disease ni, Multiple Sclerosis ni, Mumps ni, Myasthenia Gravis ni, Myeloproliferative Neoplasm ni, Neck Trauma ni, Neonatal Hearing Impairment ni, Neoplasm ni, Neurofibromatosis ni, Neutropenic Disorder ni, Non-Neoplastic Central Nervous System Disorder ni, Obesity ni, Obstructive Sleep Apnea Syndrome ni, Opioid Use Disorder ni, Optic Neuritis ni, Osteoporosis ni, Palmar Fibromatosis ni, Pancytopenia ni, Parkinson's Disease ni, Penicillin Allergy ni, Personality Disorder ni, Pituitary Neuroendocrine Tumor ni, Pleural Effusion ni, Pneumococcal Pneumonia ni, Pneumonia ni, Pneumonia Caused By SARS-CoV-2 ni, Post-Herpetic Neuralgia ni, Primary Neoplasm ni, Primary Progressive Aphasia ni, Progressive Multifocal Leukoencephalopathy ni, Prolapsed Lumbar Intervertebral Disc ni, Proteinuria ni, Psoriasis ni, Psoriatic Arthritis ni, Psychiatric Disorder ni, Pulmonary Embolism ni, Pulmonary Sarcoidosis ni, Pulmonary Thromboembolism ni, Radius Fracture ni, Renal Colic ni, Retinal Detachment ni, Rheumatoid Arthritis ni, Sarcoidosis ni, Scarlet Fever ni, Seizure Disorder ni, Serositis ni, Serum Glutamic Pyruvic Transaminase, CTCAE ni, Shoulder Dislocation ni, Sign ni, Sign or Symptom ni, Sinusitis ni, Sjogren Syndrome ni, Skin Basal Cell Carcinoma ni, Skin Basosquamous Cell Carcinoma ni, Skin Carcinoma ni, Skin Cyst ni, Spina Bifida ni, Spinal and Bulbar Muscular Atrophy, X-linked 1 ni, Staphylococcal Infection ni, Stroke ni, Subdural Hematoma ni, Symptom ni, Syncope ni, Thalassemia ni, Thoracic Trauma ni, Thrombocytopenia ni, Thromboembolism ni, Thyroid Gland Disorder ni, Thyroiditis ni, Tibia Fracture ni, Tinea Versicolor ni, Tooth Abscess ni, Toxoplasmosis ni, Transient Ischemic Attack ni, Trigeminal Nerve Disorder ni, Two Vessel Coronary Disease ni, Type 1 Diabtes Mellitus ni, Type 2 Diabetes Mellitus ni, Ureteral Stenosis ni, Uterine Corpus Leiomyoma ni, Vertigo ni, Viral Pericarditis ni, Vitiligo ni, Vulvovaginal Candidiasis ni, Vulvovaginitis ni

Electromyographyc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/Electromyography

An assessment of skeletal muscle function and nerve control, obtained by recording and studying the intrinsic electrical properties of the muscles. [Defintion Source: NCI]
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/42803009
has super-classes
Diagnostic Procedure c
is in domain of
conductionBlocks dp, electromyographyOutcome dp

End Therapy Reasonc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/EndTherapyReason

The motivation for the interruption of the therapeutic treatment.
is in domain of
adverseReaction op, confirmedPregnancy op, endTherapyReason dp

Eventc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Event

Something that happens at a given place and time. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25499
has sub-classes
Before Onset c, Diagnosis c, Onset c, Protocol Event c
is in domain of
consists op, eventEnd dp, eventStart dp, hasRegisteredActivity op, hasRegisteredCondition op, pregnancy op, relapse op, trauma op
is in range of
undergo op

Evoked Potentialsc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/EvokedPotentials

Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. [Definition Source: MSH]
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/386205007
has super-classes
Diagnostic Procedure c
is in domain of
evokedPotentialsLocation dp, evokedPotentialsResponse dp, evokedPotentialsType dp, visualEvokedPotentialAmplitude dp, visualEvokedPotentialLatency dp

Expanded Disability Status Scale (EDSS)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/EDSS

A system for quantifying disability in multiple sclerosis (MS). Based on a standard neurological examination, the Expanded Disability Status Scale quantifies disability in seven Functional Systems (plus "Other") and assigns a Functional System Score in each. Results are ranked as steps from 0 to 10, with steps 1 through 4.5 describing MS patients who are fully ambulatory and steps 5 through 9.5 describing increasing impairment to ambulation. Step 10 refers to death due to MS. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C98302
has super-classes
Diagnostic Procedure c
is in domain of
ambulationEDSS dp, bowelAndBladderEDSS dp, brainstemEDSS dp, cerebellarEDSS dp, cerebralEDSS dp, clinicallyEvaluatedEDSS dp, pyramidalEDSS dp, sensoryEDSS dp, visualEDSS dp

Fatigue Severity Score (FSS)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/FSS

FSS (Fatigue Severity Scale) is a patient-reported questionnaire used to assess the impact of fatigue on daily life in multiple sclerosis. Analyzing FSS scores alongside brain connectivity metrics can help understand how MS-related brain changes relate to fatigue severity and the efficiency of relevant brain networks.
Is defined by
http://purl.obolibrary.org/obo/NCIT_C106621
has super-classes
Self-Reported Questionnaire c

Genec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Gene

A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16612
is in range of
onGene op
has members
AR Gene ni, C9orf72 Gene ni, DCTN1 Gene ni, FUS Gene ni, OPTN Gene ni, SOD1 Gene ni, SQSTM1 Gene ni, TARDBP Gene ni, TBK1 Gene ni

Genetic Testingc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/GeneticTesting

The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C15709
is in domain of
hasMutation dp, mutationType dp, onGene op
is in range of
tested op

Group (social concept)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Group

A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender) [Definition Source: NCI]
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/389109008
is in range of
hasEthnicity op
has members
Asian (ethnic group) ni, Black (ethnic group) ni, Caucasian ni, Ethnic Group ni, Hispanic ni

Hematology Testc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/HematologyTest

A laboratory test to measure hematopoietic components and investigate hematologic disorders in a blood sample. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C49286
has super-classes
Diagnostic Procedure c
is in domain of
observedResult op

Hoffman's Reflex Testc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/HoffmanReflex

A Hoffmann test is performed by flicking the fingernail of the long finger, from dorsal to volar, on each hand while the hand was supported by the examiner's hand. The test was done with the neck in the neutral position and then with the neck maximally forward flexed. Any flexion of the ipsilateral thumb and/or index finger was interpreted as a positive test. [PMID:11813951, PMID:20229121]
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/74229007
has super-classes
Diagnostic Procedure c
is in domain of
hoffmanLeft dp, hoffmanRight dp

Impairmentc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Impairment

Loss or abnormality of psychological, physiological, or anatomic structure or function. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C21055
has super-classes
Conditon c

Intervention or Procedurec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/InterventionOrProcedure

An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25218
has sub-classes
Diagnostic Procedure c, Surgical Procedure c, Therapeutic Procedure c
is in domain of
procedureEnd dp, procedureStart dp
is in range of
consists op

King's Clinical Staging Methodc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/KingsClinicalStaging

The King’s staging system consists of five disease stages, with Stage 5 being death. Stages 1–3 are based upon the number of El Escorial central nervous system (CNS) regions involved in the disease, measured by weakness, wasting, spasticity, dysphagia, or dysarthria. Stage 4 is nutritional failure, defined by the requirement for gastrostomy, or respiratory failure, defined by the requirement for noninvasive ventilation (NIV), and based upon the National Institute for Clinical Excellence MND Guidelines (Supplemental Material). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]
has super-classes
Questionnaire c
is in domain of
kingsValue dp

Kinshipc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Kinship

The relationship between members of the same family. [Cambridge Dictionary]
Is defined by
https://dictionary.cambridge.org/dictionary/english/kinship
is in domain of
hasKinshipType op, inKinshipWith op
is in range of
hasKinship op

KinshipTypec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/KinshipType

The type of the relationship between members of the same family.
is in range of
hasKinshipType op
has members
Aunt ni, Brother ni, Cousin ni, Daughter ni, Father ni, First Cousin ni, First Degree Relative ni, Granddaughter ni, Grandfather ni, Grandmother ni, Grandson ni, Maternal Aunt ni, Maternal Uncle ni, Mother ni, Nephew ni, Niece ni, Paternal Aunt ni, Paternal Uncle ni, Relative ni, Second Degree Relative ni, Sister ni, Son ni, Third Degree Relative ni, Uncle ni

Laboratory Test Resultc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/LaboratoryTestResult

The outcome of a laboratory test. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C36292
is in domain of
componentName dp, measuredLevel dp, normalLevel dp, positivityResult dp, unitOfMeasure dp
is in range of
observedResult op

Last 5 Years Eventc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Last5YearsEvent

Events occurred in the last 5 years (from the first visit).
has super-classes
Before Onset c

Lesion Topography Score (LTS)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/LTS

LTS (Lesion Topography Score) quantifies lesion distribution in the brains of multiple sclerosis patients. By examining LTS alongside brain connectivity metrics, researchers can assess how lesion location and extent affect brain network organization and communication efficiency, potentially influencing cognitive and motor function.
has super-classes
Cognitive Assessment c

Lifestylec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Lifestyle

A manner of living that reflects the person's values and attitudes. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16795
has super-classes
Activity c
is in domain of
alcoholUse dp, diet dp, sexuality dp, sunExposure dp

Local Health Autorityc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/ASL

A Local Health Authority (Italian: azienda sanitaria locale), commonly abbreviated as ASL in Italian, or a Local Health Unit Authority, known as AUSL, is a public organization that falls under the purview of the Italian public administration. Its primary mandate is to deliver healthcare services to a specific territorial area, which is typically at the provincial level. In different regions of Italy, these entities are referred to by various designations, including ASP, ASM, ATS, and AST.
has sub-classes
Company-Socio-Health Local Autority c
is in domain of
comprisesPlace op

Magnetic Resonance Imaging (MRI)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/MRI

Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16809
has super-classes
Diagnostic Imaging c
is in domain of
brainAtrophyMRI dp, contiguousLesionsMRI dp, gadoliniumLesionsT1MRI dp, gadoliniumLesionsT1MRINumber dp, lesionsT1MRI dp, newOrEnlargedLesionsT2MRI dp, newOrEnlargedLesionsT2MRINumber dp, totalLesionsT2MRI dp
is in range of
requiredMRI op

Milano-Torino Functional Staging System (MiToS)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/MiToSFunctionalStaging

The Milano–Torino (MiToS) Staging system comprises six stages, based on functional impairment as assessed by the revised ALS Functional Rating Scale (ALSFRS-R). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]
has super-classes
Questionnaire c
is in domain of
mitosValue dp

More Than 5 Years Eventc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/MoreThan5YearsEvent

Events occured more than 5 years ago, counting from the first visit.
has super-classes
Before Onset c

Multiple Scleroris Neuropsychological Questionnaire (MSNQ)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/MSNQ

MSNQ (Multiple Sclerosis Neuropsychological Questionnaire) assesses cognitive and emotional aspects of life with multiple sclerosis, such as memory, attention, and depression. Analyzing MSNQ scores alongside brain connectivity metrics can provide insights into how MS-related brain changes impact self-reported cognitive and emotional functioning.
has super-classes
Questionnaire c

Muscle Biopsyc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/MuscleBiopsy

Removal of a small piece of muscle tissue for examination.
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/178263003
has super-classes
Diagnostic Procedure c
is in domain of
muscleBiopsyOutcome dp, performedMuscleBiopsy dp

Neurologic Examc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/NeurologicExam

The assessment of the functionality of the brain, spinal column, and nerves. [Definition Source: NCI]
Is defined by
https://uts.nlm.nih.gov/uts/umls/concept/C0027853
has super-classes
Diagnostic Procedure c
is in domain of
tongueAtrophy dp, tongueFasciculation dp, tongueNotProtruding dp, tongueProtrusion dp, tongueThrust dp

Occupationc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Occupation

The principal activity that a person does to earn money. [Definition Source: NCI]
Is defined by
http://data.europa.eu/esco/isco
is in range of
hasOccupation op
has members
Administrative and commercial managers ni, Agricultural, forestry and fishery labourers ni, Armed forces occupations ni, Armed forces occupations, other ranks ni, Assemblers ni, Building and related trades workers, excluding electricians ni, Business and administration associate professionals ni, Business and administration professionals ni, Chief executives, senior officials and legislators ni, Cleaners and helpers ni, Clerical support workers ni, Commissioned armed forces officers ni, Craft and related trades workers ni, Customer services clerks ni, Drivers and mobile plant operators ni, Electrical and electronic trades workers ni, Elementary occupations ni, Food preparation assistants ni, Food processing, wood working, garment and other craft and related trades workers ni, General and keyboard clerks ni, Handicraft and printing workers ni, Health associate professionals ni, Health professionals ni, Hospitality, retail and other services managers ni, Information and communications technicians ni, Information and communications technology professionals ni, Labourers in mining, construction, manufacturing and transport ni, Legal, social and cultural professionals ni, Legal, social, cultural and related associate professionals ni, Managers ni, Market-oriented skilled agricultural workers ni, Market-oriented skilled forestry, fishery and hunting workers ni, Metal, machinery and related trades workers ni, Non-commissioned armed forces officers ni, Numerical and material recording clerks ni, Other clerical support workers ni, Personal care workers ni, Personal service workers ni, Plant and machine operators and assemblers ni, Production and specialised services managers ni, Professionals ni, Protective services workers ni, Refuse workers and other elementary workers ni, Sales workers ni, Science and engineering associate professionals ni, Science and engineering professionals ni, Service and sales workers ni, Skilled agricultural, forestry and fishery workers ni, Stationary plant and machine operators ni, Street and related sales and service workers ni, Subsistence farmers, fishers, hunters and gatherers ni, Teaching professionals ni, Technicians and associate professionals ni

Oligoclonal Bandsc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/OligoclonalBands

The presence of more than one immunoglobulin band in the serum, urine, or cerebrospinal fluid. It usually results from infectious or immunologic disorders. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C113809
is in domain of
oligoclonalBandsNumber dp, oligoclonalBandsPresence dp, oligoclonalBandsType dp
is in range of
testedForOligoclonalBands op

Onsetc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Onset

The start, beginning, or early stages. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25279
has super-classes
Event c
is in domain of
ageOnset dp, axialOnset dp, bulbarOnset dp, generalizedOnset dp, limbsOnset dp, otherOnset dp

Paced Auditory Serial Addition Test (PASAT)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/PASAT

PASAT (Paced Auditory Serial Addition Test) assesses information processing speed and calculation ability in multiple sclerosis patients. By correlating PASAT scores with brain connectivity metrics, researchers can identify how MS affects brain networks involved in attention,working memory, and cognitive processing.
Is defined by
http://purl.obolibrary.org/obo/NCIT_C115792
has super-classes
Cognitive Assessment c

Patientc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Patient

A person who receives medical attention, care, or treatment, or who is registered with medical professional or institution with the purpose to receive medical care when necessary. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C16960
has super-classes
Person c
is in domain of
MSInPaediatricAge dp, alive dp, deathCause dp, deathDate dp, dextricity dp, educationLevel dp, everSmoked dp, genomeSequencing dp, hasEthnicity op, hasKinship op, hasOccupation op, maritalStatus dp, menopauseStatus dp, notes dp, retiredAtDiagnosis dp, tested op, undergo op

Personc back to ToC or Class ToC

IRI: http://www.w3.org/2000/10/swap/pim/contact#Person

A human being. [Definition Source: NCI]
has sub-classes
Patient c
is in domain of
birthYear dp, birthplace op, enrolledIn op, hasDisease op, residence op, sex dp
is in range of
inKinshipWith op
has members
Gianmaria Silvello ni, Giorgio Maria Di Nunzio ni, Guglielmo Faggioli ni, Laura Menotti ni, Nicola Ferro ni, Stefano Marchesin ni

Pharmacologic Substancec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/PharmacologicSubstance

Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C1909
is in range of
pharmacologicSubstance op
has members
ACE Inhibitors, Plain ni, Acetylcarnitine ni, Acetylsalicylic Acid, Combinations excl. Psycholeptics ni, Aciclovir ni, Ademetionine ni, Agents Acting on the Renin-Angiotensin System ni, Alectinib ni, Alemtuzumab ni, Alimentary Tract and Metabolism ni, All Other Non-Therapeutic Products ni, All Other Therapeutic Products ni, Allergens ni, Alpha-Lipoic Acid ni, Alprazolam ni, Amantadine ni, Amiodarone ni, Amitriptyline ni, Amitriptyline and Psycholeptics ni, Amlodipine ni, Amoxicillin and Beta-Lactamase Inhibitor ni, Anabolic Agents for Systemic Use ni, Analgesics ni, Anesthetics ni, Anthelmintics ni, Anti-Acne Preparations ni, Anti-Parkinson Drugs ni, Antianemic Preparations ni, Antibacterials for Systemic Use ni, Antibiotics and Chemotherapeutics for Dermatological Use ni, Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents ni, Antiemetics and Antinauseants ni, Antiepileptics ni, Antifungals for Dermatological Use ni, Antigout Preparations ni, Antihemorrhagics ni, Antihistamines for Systemic Use ni, Antihypertensives ni, Antiinfectives for Systemic Use ni, Antiinflammatory and Antirheumatic Products ni, Antimycobacterials ni, Antimycotics for Systemic Use ni, Antineoplastic Agents ni, Antineoplastic and Immunomodulating Agents ni, Antiobesity Preparations, excl. Diet Products ni, Antiparasitic Products, Insecticides and Repellents ni, Antiprotozoals ni, Antipruritics, incl. Antihistamines, Anesthetics, etc. ni, Antipsoriatics ni, Antispetic and Disinfectants ni, Antithrombotic Agents ni, Antivirals for Systemic Use ni, Appetite Stimulants ni, Atenolol ni, Atenolol and Other Diuretics ni, Atrovastatin ni, Azathioprine ni, BCG Vaccine ni, BG-12 ni, Baclofen ni, Barbexaclone ni, Barnidipine ni, Beta Blocking Agents ni, Betahistine ni, Betamethasone ni, Bile Therapy ni, Bile and Liver Therapy Drugs ni, Biotin ni, Bisoprolol ni, Blood Substitutes and Perfusion Solutions ni, Blood and Blood Forming Organs ni, Botulinum Toxin ni, Bromazepam ni, Brotizolam ni, Cabergoline ni, Calcifediol ni, Calcium Channel Blockers ni, Calcium Folinate ni, Calcium Homeostasis ni, Calcium, Combinations with Vitamin D and/or Other Drugs ni, Cannabinoids ni, Carbamazepine ni, Cardiac Therapy ni, Cardiovascular System ni, Ceftriaxone ni, Cetirizine ni, Chlorphenamine ni, Cinnarizine ni, Cinnarizine, Combinations ni, Citalopram ni, Cladribine ni, Cladribine ni, Clobazam ni, Clonazepam ni, Clopidogrel ni, Codeine, Combinations excl. Psycholeptics ni, Colecalciferol ni, Contrast Media ni, Corticosteroids for Systemic Use ni, Corticosteroids, Dermatological Preparations ni, Corticotropin ni, Cough and Cold Preparations ni, Covid-19 Vaccines ni, Cyanocobalamin ni, Cyclophosphamide ni, Daclizumab ni, Dantrolene ni, Deflazacort ni, Denosumab ni, Dermatologicals ni, Desogestrel and Ethinylestradiol ni, Dexamethasone ni, Diagnostic Agents ni, Diagnostic Radiopharmaceuticals ni, Diazepam ni, Dietary Supplement ni, Digestives, incl. Enzymes ni, Dimethyl Fumarate ni, Diphtheria Vaccines ni, Diuretics ni, Domperidone ni, Drospirenone and Ethinylestradiol ni, Drugs Used in Diabetes ni, Drugs for Acid Related Disorders ni, Drugs for Bile Therapy and Lipotropics in Combination ni, Drugs for Constipation ni, Drugs for Functional Gastrointestinal Disorders ni, Drugs for Obstructive Airway Diseases ni, Drugs for Treatment of Bone Diseases ni, Ectoparasiticides, incl. Scabicides, Insecticides and Repellents ni, Ecunerv ni, Emollients and Protectives ni, Enalapril ni, Endocrine Therapy ni, Escitalopram ni, Esomeprazole ni, Etizolam ni, Etoricoxib ni, Fampridine ni, Fingolimod ni, Flunarizine ni, Fluoxetine ni, Flurazepam ni, Furosemide ni, Gabapentin ni, General Nutrients ni, Genito Urinary System and Sex Hormones ni, Glatiramer Acetate ni, Gliclazide ni, Glimepiride ni, Glucocorticoids, Systemic ni, Gynecological Antiinfectives and Antiseptics ni, Hepatitis B, Purified Antigen ni, Hydrocortisone ni, Hydrocortisone ni, Hydroxychloroquine ni, Hypnotics and Sedatives ni, Ibuprofen ni, Immune Sera and Immunoglobulins ni, Immunoglobulins, Normal Human, for Intravascular Adm. ni, Immunostimulants ni, Immunosuppressants ni, Indometacin ni, Insulin Glargine ni, Insulin Lispro ni, Insulins and Analogues ni, Interferon Beta Natural ni, Interferon Beta-1a ni, Interferon Beta-1b ni, Ketorolac ni, Lactulose ni, Lamotrigine ni, Lercanidipine ni, Levetiracetam ni, Levodopa and Decarboxylase Inhibitor ni, Levothyroxine Sodium ni, Lipid Modifying Agents ni, Liver Therapy, Lipotropics ni, Losartan ni, Malgradate ni, Medicated Dressings ni, Melatonin ni, Mesalazine ni, Metformin ni, Methotrexate ni, Methotrexate ni, Methylprednisolone ni, Mineral Supplements ni, Mitoxantrone ni, Mitrazapine ni, Modafinil ni, Muscle Relaxants ni, Musculo-Skeletal System ni, Naltrexone ni, Nasal Preparations ni, Natalizumab ni, Nebivolol ni, Nervous System ni, Nicergoline ni, Ocrelizumab ni, Olanzapine ni, Olmesartan Medoxomil ni, Ophthalmologicals ni, Ophthalmologicals and Otologicals Products ni, Other Alimentary Tract and Metabolism ni, Other Dermatological Preparations ni, Other Drugs for Disorders of the Musculo-Skeletal System ni, Other Gynecologicals ni, Other Hematological Agents ni, Other Nervous System Drugs ni, Other Respiratory System Products ni, Other Vaccines ni, Otologicals ni, Oxcarbazepine ni, Oxybutynin ni, Paliperidone ni, Pancreatic Hormones ni, Pantoprazole ni, Paracetamol ni, Paroxetine ni, Peginterferon Alfa-2b ni, Peginterferon Beta-1a ni, Perindopril and Amlodipine ni, Peripheral Vasodilators ni, Phenobarbital ni, Phenytoin ni, Pituitary and Hypothalamic Hormones and Analogues ni, Poliomyelitis, Trivalent, Inactivated, Whole Virus ni, Pramipexole ni, Prasugrel ni, Prazepam ni, Prednisolone ni, Prednisone ni, Pregabalin ni, Preparations for Treatment of Wounds and Ulcers ni, Progestogens and Estrogens Systemic Contraceptives, Sequential Preparations ni, Proglumide ni, Propanolol ni, Psychoanaleptics ni, Psycholeptics ni, Quetiapine ni, Ramipril ni, Reboxetine ni, Respiratory System ni, Rifampicin ni, Riluzole ni, Rituximab ni, Rivaroxaban ni, Rivastigmine ni, Ropinirole ni, Secukinumab ni, Sensory Organs ni, Sertraline ni, Sex Hormones and Modulators of the Genital System ni, Sildenafil ni, Simvastatin ni, Siponimod ni, Sitagliptin ni, Stomatological Preparations ni, Sulfasalazine ni, Surgical Dressings ni, Systemic Hormonal Preparations, excl. Sex Hormones and Insulins ni, Tamoxifen ni, Tamsulosin ni, Telmisartan ni, Teriflunomide ni, Tetanus Immunoglobulin ni, Tetracosactide ni, Therapeutic Radiopharmaceuticals ni, Thiamazole ni, Thiethylperazine ni, Throat Preparations ni, Thyroid Therapy ni, Ticlopidine ni, Tizanidine ni, Tocilizumab ni, Tolterodine ni, Tonics ni, Topical Products for Joint and Muscular Pain ni, Topiramate ni, Trastuzumab ni, Trazodone ni, Triazolam ni, Trospium ni, Urologicals ni, Ursodeoxycholic Acid ni, Ustekinumab ni, Vaccines ni, Valaciclovir ni, Valproic Acid ni, Various ni, Vasoprotectives ni, Venlafaxine ni, Verapamil ni, Vigabatrin ni, Vitamins ni, Warfarin ni, Zolmitriptan ni, Zolpidem ni, Zuclopenthixol ni

Physical Activityc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/PhysicalActivity

Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI][attribution: from NIDDK Glossary; http://www.niddk.nih.gov/health/nutrit/pubs/glossary/glossaryintro.htm]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C17708
has super-classes
Activity c
is in domain of
activityType dp, intensity dp, weeklyFrequency dp

Placec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Place

A particular part or region of space; a physical locality, a locale; a spot, a location. [Definition Source: Oxford English Dictionary]
is in domain of
placeArea dp, zipCode dp, zipHashed dp
is in range of
birthplace op, comprisesPlace op, coveredPlace op, placeLocation op

Plantar Reflex Testc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/PlantarReflex

Test of the cutaneous-plentar reflex.
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/91365008
has super-classes
Diagnostic Procedure c
is in domain of
leftPlantarReflex dp, rightPlantarReflex dp

Positron Emission Tomography (PET)c back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/PET

A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C17007
has super-classes
Diagnostic Imaging c
is in domain of
petOutcome dp

Pregnancyc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Pregnancy

The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25742
is in domain of
pregnancyComplications dp, pregnancyEnd dp, pregnancyEndEvent dp, pregnancyStart dp
is in range of
coexistingPregnancy op, confirmedPregnancy op, pregnancy op

Protocol Eventc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ProtocolEvent

Other important events that occur during a trial but are not driven by protocol requirements. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C74589
has super-classes
Event c

Pulmonary Function Testc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/PulmonaryFunctionTest

A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C38081
has super-classes
Diagnostic Procedure c
is in domain of
pulmonaryAOPAbs dp, pulmonaryFEV6 dp, pulmonaryFVCRel dp, pulmonaryMEPAbs dp, pulmonaryMIPAbs dp, pulmonaryPCO2 dp, pulmonaryPO2 dp, pulmonaryVCAbs dp

Questionnairec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Questionnaire

A predetermined set of questions. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C17048
has super-classes
Diagnostic Procedure c
has sub-classes
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c, King's Clinical Staging Method c, Milano-Torino Functional Staging System (MiToS) c, Multiple Scleroris Neuropsychological Questionnaire (MSNQ) c, Self-Reported Questionnaire c

Relapsec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Relapse

The return of a disease after a period of remission. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C38155
is in domain of
bowelAndBladderRelapse dp, brainstemRelapse dp, cerebellarRelapse dp, coexistingPregnancy op, cognitiveRelapse dp, furtherRelapseBeforePL dp, otherRelapse dp, pyramidalRelapse dp, relapseClinicalTherapy dp, relapseCortisoneTherapy dp, relapseDuration dp, relapseEnd dp, relapseHospitalAdmission dp, relapseImpactOnADL dp, relapseRecovery dp, relapseSequela dp, relapseSeverity dp, relapseStart dp, requiredMRI op, sensoryRelapse dp, visualRelapse dp
is in range of
relapse op

Residencec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Residence

Any address at which a person dwells more than temporarily. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C25273
is in domain of
placeLocation op, residenceEnd dp, residenceStart dp
is in range of
residence op

Risk Factorc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/RiskFactor

Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C17103
has super-classes
Activity c
is in domain of
electricTraumaRisk dp, herbicidesRisk dp, metalsRisk dp, pesticidesRisk dp, polioRisk dp, solventsRisk dp, sportRisk dp, traumaRisk dp

Selective Reminding Test - Delayedc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/SRTD

SRT-D (Selective Reminding Test – Delayed) assesses long-term verbal memory in multiple sclerosis patients by evaluating their ability to recall a word list after a delay. Combining SRT-D scores with brain connectivity metrics can reveal how MS affects memory consolidation and retrieval networks, and the efficiency of information flow within these networks.
has super-classes
Cognitive Assessment c

Self-Reported Questionnairec back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/SelfQuestionnaire

A questionnaire reported by the patient.
has super-classes
Questionnaire c
has sub-classes
Beck Depression Inventory-II (BDI-II) c, Fatigue Severity Score (FSS) c

Smokingc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Smoking

The act of puffing and/or inhaling the combustion products of a substance so as to be tasted and absorbed into the bloodstream. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C154329
has super-classes
Activity c
is in domain of
before20Years dp, dailyCigarettes dp, packYear dp

Spatial Recall Test (SPART)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/SPART

SPART (Spatial Recall Test) assesses spatial learning and memory in multiple sclerosis patients by evaluating their ability to recall the location of objects on a board. Combining SPART scores with brain connectivity metrics can reveal how MS affects spatial memory networks and their efficiency, integration, and role in information flow.
has super-classes
Cognitive Assessment c

Surgical Procedurec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/SurgicalProcedure

A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C15329
has super-classes
Intervention or Procedure c
is in domain of
surgicalType op

Surgical Procedure Typec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/SurgicalType

It defines some type of surgical procedures a patient could undergo.
is in range of
surgicalType op
has members
Abdominoplasty ni, Appendectomy ni, Cardioversion ni, Cholecystectomy ni, Cone Biopsy ni, Coronary Artery Bypass Graft ni, Drainage of Bartholin's Abscess ni, Emergency Tracheostomy ni, Excision of Basal Cell Carcinoma ni, Excision of Benign Neoplasm ni, Excision of Cyst ni, Excision of Neoplasm ni, Excision of dermatofibroma ni, Gastroplasty ni, Gastryc Bypass ni, Head and Neck Approaches ni, Head and Neck Surgery ni, Hysterectomy ni, Insertion of Implantable Intrathecal Access System ni, Operation on Abdominal Region ni, Operative Procedure on Lumbosacral Spinal Structure ni, Operative Procedure on Thoracic Spinal Structure ni, Operative Procedure on Upper Extremity ni, Partial Cystectomy ni, Percutaneous Endoscopic Gastrostomy (PEG) ni, Procedure on Pelvic Region of Trunk ni, Removal of Acoustic Neuroma ni, Repair of Bladder ni, Surgical Procedure on Cervical Spine ni, Surgical Procedure on Lower Extremity ni, Surgical Procedure on Thorax ni, Thyroid Gland Excision ni, Transurethral Prostatectomy ni

Symbol Digit Modalities Test (SDMT)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/SDMT

Symbol Digit Modalities Test. It is a neuropsychological test used to assess cognitive function, particularly attention,visual scanning, and motor speed. The SDMT involves matching symbols with numbers under a time constraint.
Is defined by
http://purl.obolibrary.org/obo/NCIT_C115793
has super-classes
Cognitive Assessment c

Symbol Digit Modalities Test - Delayed (SPART-D)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/SPARTD

SPART-D: Symbol Digit Modalities Test – Delayed (delayed recall version of the SPART)
has super-classes
Cognitive Assessment c

Tendon Reflex Testc back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/TendonReflex

Tendon Reflex Test
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/246581004
has super-classes
Diagnostic Procedure c
is in domain of
lowerLimbsTendonReflex dp, upperLimbsTendonReflex dp

Therapeutic Procedurec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/TherapeuticProcedure

An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C49236
has super-classes
Intervention or Procedure c
is in domain of
performedTreatment op

Therapeutic Procedure Typec back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/TherapeuticProcedureType

It defines some type of therapeutic procedures that could be administered to a patient.
is in range of
therapyType op
has members
Anticonvulsant Agent ni, Cortisone Therapy for Relapse ni, Drugs for MS Symptomatic Therapy ni, Drugs for MS Therapy Side Effects ni, Drugs for Other Diseases ni, Immunoactive Drugs ni, Non-Invasive Mechanical Ventilation (NIV) ni, Plasmapheresis ni

Therapeutic Treatmentc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/TherapeuticTreatment

The therapeutic treatment that has been administered to a patient.
is in domain of
administration op, pharmacologicSubstance op, therapyType op
is in range of
performedTreatment op

Traumac back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/Trauma

Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]
Is defined by
http://purl.obolibrary.org/obo/NCIT_C3671
is in domain of
traumaDate dp, traumaDescription dp
is in range of
trauma op

Use-Case Comorbiditiesc back to ToC or Class ToC

IRI: https://w3id.org/brainteaser/ontology/schema/UseCaseComorbidities

Comorbidities checked in a specific use-case, e.g. ALS patients in a specific study.
has super-classes
Comorbidity c
has sub-classes
ALS Brainteaser Comorbidities c

Word List Generation (WLG)c back to ToC or Class ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/WLG

WLG: Word List Generation (a measure of verbal fluency)
has super-classes
Cognitive Assessment c

Object Properties

administrationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/administration

It defines the relationship between a therapeutic treatment and the specific administration details.
has domain
Therapeutic Treatment c
has range
Administration c

adverseReactionop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/adverseReaction

It defines the relationship between The end therapy reason and the adverse reaction occurred.
has domain
End Therapy Reason c
has range
Adverse Drug Reaction c

anatomicalLocationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/anatomicalLocation

It defines the location of a trauma, onset, surgical procedure or diagnostic imaging.
has domain
Diagnostic Imaging c or Onset c or Surgical Procedure c or Trauma c
has range
Anatomic Site c

APConcentrationTimeop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/APConcentrationTime

It defines the relationship between air pollution conentration individuals and their time of recording.
has domain
air pollution concentration c
has range
instant c

birthplaceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/birthplace

It defines the relationship between a person and his or her birthplace.
has domain
Person c
has range
Place c

coexistingPregnancyop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/coexistingPregnancy

It defines the relationship between a relapse and a co-occurring pregnancy.
has domain
Relapse c
has range
Pregnancy c

comprisesPlaceop back to ToC or Object Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/comprisesPlace

links the Local Health Autority to the administred territories.
has domain
Local Health Autority c
has range
Place c

conductedInClinicop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/conductedInClinic

It defines the relationship between a clinical trial and a clinic or hospital. In particular, a clinical trial is conducted in a clinic or hospital.
has domain
Clinical Trial c
has range
Clinics and Hospitals c

confirmedPregnancyop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/confirmedPregnancy

It defines the relationship between the end therapy reason and a pregnancy, meaning the therapeutic treatment was interrupted due to a confirmed pregnancy.
has domain
End Therapy Reason c
has range
Pregnancy c

consistsop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/consists

It defines the relationship between an event and an intervetion or procedure. In particular, an event could consist in an intervention or procedure.
has domain
Event c
has range
Intervention or Procedure c

coveredPlaceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/coveredPlace

It defines the relationship between the sensing device for environmental data and the covered place.
has domain
sensing device c
has range
Place c

determinedByop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/determinedBy

It defines the relationship between a comorbidity and the disease that determines it.

has characteristics: functional

has domain
Comorbidity c
has range
Disease, Disorder or Finding c

enrolledInop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/enrolledIn

It defines the relationship between a person and a clinical trial participation. In particular, a person can be enrolled in a clinical trial participation.
has domain
Person c
has range
Clinical Trial Participation c

hasDiseaseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasDisease

It defines the relationship between a person and a disease which he or she suffers from.
has domain
Person c
has range
Disease, Disorder or Finding c

hasEthnicityop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasEthnicity

It defines the patient's ethnicity. For instance, we say that: :Peter :hasEthnicity _:b . _:b a Group (social concept); a skos:Concept.

has characteristics: functional

has domain
Patient c
has range
Group (social concept) c

hasKinshipop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasKinship

It defines the relation between a patient and a kinship. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.

has characteristics: functional

has domain
Patient c
has range
Kinship c

hasKinshipTypeop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasKinshipType

It defines the relation between a Kinship and a KinshipType. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.

has characteristics: functional

has domain
Kinship c
has range
KinshipType c

hasOccupationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasOccupation

It defines the relationship between a patient and his or her occupation.

has characteristics: functional

has domain
Patient c
has range
Occupation c

hasRegisteredActivityop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRegisteredActivity

It defines the relationsihip between an event and an activity. In particular, during an event a specific type of activity can be registered.
has domain
Event c
has range
Activity c

hasRegisteredConditionop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasRegisteredCondition

It defines the relationsihip between an event and a comorbidity. In particular, during an event a preexisting condition can be registered.
has domain
Event c
has range
Conditon c

inClinicalTrialop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/inClinicalTrial

It defines the relationship between a clinical trial participation and a clinical trial. In particular, a clinical trial participation refers to a clinical trial.

has characteristics: functional

has domain
Clinical Trial Participation c
has range
Clinical Trial c

inKinshipWithop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/inKinshipWith

The relationship of kinship between a patient with another Person (who might also be a Patient)
has domain
Kinship c
has range
Person c

is produced byop back to ToC or Object Property ToC

IRI: http://purl.oclc.org/NET/ssnx/ssn#isProducedBy

Relation between a producer and a produced entity: for example, between a sensor and the produced output.
Is defined by
http://purl.oclc.org/NET/ssnx/ssn
has domain
air pollution concentration c
has range
sensing device c

isAboutDiseaseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/isAboutDisease

It defines the relationship between a clinical trial and the disease studied in it.
has domain
Clinical Trial c
has range
Disease, Disorder or Finding c

observedResultop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/observedResult

It defines the relationship between an hematology test and the observed laboratory results.
has domain
Hematology Test c
has range
Laboratory Test Result c

onGeneop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/onGene

It defnies the relationship between a genetic testing and a gene. In particular, a genetic testing looks for some genetic mutations on a gene.
has domain
Genetic Testing c
has range
Gene c

performedTreatmentop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/performedTreatment

It defines the relationship between the therapeutic procedure and the perfomed therapeutic treatments.
has domain
Therapeutic Procedure c
has range
Therapeutic Treatment c

pharmacologicSubstanceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pharmacologicSubstance

It defines the relationship between a therapeutic treatment and the employed pharmacologic subastance.
has domain
Therapeutic Treatment c
has range
Pharmacologic Substance c

placeLocationop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/placeLocation

It defines the relationship between a patient's residence and its location.

has characteristics: functional

has domain
Residence c
has range
Place c

pregnancyop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pregnancy

It defines the relationship between an event and a pregnancy that can be registrered during the event.
has domain
Event c
has range
Pregnancy c

relapseop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapse

It defines the relationship between an event and a relapse that can be registered during the event.
has domain
Event c
has range
Relapse c

requiredMRIop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/requiredMRI

It defines the relationship between a relapse and a MRI that has been required.
has domain
Relapse c
has range
Magnetic Resonance Imaging (MRI) c

residenceop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/residence

It defines the relationship between a person and his or her residence.
has domain
Person c
has range
Residence c

surgicalTypeop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/surgicalType

It defines the realtionship between the surgical procedure and the specific type of surgical procedure.

has characteristics: functional

has domain
Surgical Procedure c
has range
Surgical Procedure Type c

testedop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/tested

It defines the relationship betwen a patient and a genetic testing. In particular, a patient can be tested for genetic mutations.
has domain
Patient c
has range
Genetic Testing c

testedForOligoclonalBandsop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/testedForOligoclonalBands

It defines the relationship between a CSF Analysis and a test for the presence of oligoclonal bands.

has characteristics: functional

has domain
CSF Analysis c
has range
Oligoclonal Bands c

therapyTypeop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/therapyType

It defines the relationship between the therapeutic treatment and the type of therapeutic procedure that has been administered.
has domain
Therapeutic Treatment c
has range
Therapeutic Procedure Type c

traumaop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/trauma

It defines the relationship between an event and a trauma that can be registered during the event.
has domain
Event c
has range
Trauma c

undergoop back to ToC or Object Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/undergo

It defines the relationship between patient and event. In particular, a patient can undergo some events.
has domain
Patient c
has range
Event c

unit of measureop back to ToC or Object Property ToC

IRI: http://www.wurvoc.org/vocabularies/om-1.8/unit_of_measure

has domain
air pollution concentration c
has range
unit of measure c

Data Properties

abdominalSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/abdominalSurgery

Whether a patient had an abdominal surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

acitivityStartYeardp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/activityStartYear

The year in which the activity started.

has characteristics: functional

has domain
Activity c
has range
g year

activityEndYeardp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/activityEndYear

The year in which an activity ended.

has characteristics: functional

has domain
Activity c
has range
g year

activityTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/activityType

The type of physical activity carried out.
has domain
Physical Activity c
has range
plain literal

administrationDosedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/adminstrationDose

A definite quantity of a medicine or drug given or prescribed to be given at one time. [Definition Source: Oxford English Dictionary]

has characteristics: functional

has domain
Administration c
has range
float

administrationFrequencydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/administrationFrequency

The frequency of administration of the pharmacological substance.

has characteristics: functional

has domain
Administration c
has range
plain literal

administrationRoutedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/administrationRoute

Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. [Definition Source: NCI][attribution: ICH]

has characteristics: functional

has domain
Administration c
has range
plain literal

administrationUoMdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/administrationUoM

The Unit of Measure (UoM) of the adminstration dose.

has characteristics: functional

has domain
Administration c
has range
plain literal

ageOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ageOnset

Age of the patient at the onset.

has characteristics: functional

has domain
Onset c
has range
float

albuminCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/albuminCSF

A quantitative measurement of albumin present in a sample of CSF. Unit of measure : [mg/l].

has characteristics: functional

has domain
CSF Analysis c
has range
float

alcoholUsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alcoholUse

Whether a patient drinks alcohol.

has characteristics: functional

has domain
Lifestyle c
has range
boolean

alivedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alive

Whether the patient is still alive.

has characteristics: functional

has domain
Patient c
has range
boolean

alsfrs1dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs1

Item 1 for ALSFRS: Speech.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs10dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs10

Item 10 for Revised ALSFRS: Dyspnea.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs11dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs11

Item 11 for Revised ALSFRS: Orthopnea.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs12dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs12

Item 12 for Revised ALSFRS: Respiratory Insufficiency.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs2dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs2

Item 2 for ALSFRS: Salivation.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs3dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs3

Item 3 for ALSFRS: Swallowing.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs4dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs4

Item 4 for ALSFRS: Handwriting.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs5dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs5

Item 5 for ALSFRS: Cutting food and handling utensilis.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs6dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs6

Item 6 for ALSFRS: Dressing and hygiene.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs7dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs7

Item 7 for ALSFRS: Turning in bed and adjusting blankets.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs8dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs8

Item 8 for ALSFRS: Walking.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrs9dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrs9

Item 9 for ALSFRS: Climbing Stairs.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alsfrsOriginal10dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alsfrsOriginal10

Original item 10 for ALSFRS: Breathing.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

alterationCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/alterationCSF

Whether the CSF specimen is normal or presents alterations.

has characteristics: functional

has domain
CSF Analysis c
has range
{ "atypical alteration for MS" , "normal" , "traumatic" , "typical alteration for MS" }

ambulationEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ambulationEDSS

Expanded Disability Status Score (EDSS) score for ambulation.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

autoimmuneDiseasedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/autoimmuneDisease

Whether a patient ever had an autoimmune disease.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

axialOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/axialOnset

Whether the patient experienced axial onset. The Axial Skeleton is the part of the skeleton that includes the skull and spinal column and sternum and ribs. [Definition Source: NCI]

has characteristics: functional

has domain
Onset c
has range
boolean

before20Yearsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/before20Years

Whether a patient smoked before the age of 20.

has characteristics: functional

has domain
Smoking c
has range
boolean

betweenessCentralityCoefficientdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/betweenessCentralityCoefficient

The coefficient of betweeness centrality for connectivity tests.
has domain
Cognitive Assessment c
has range
float

birthYeardp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/birthYear

The year in which a person was born. [Definition Source: NCI]

has characteristics: functional

has domain
Person c
has range
g year

bloodGasPCO2dp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/bloodGasPCO2

The level of PCO2 in the blood.
has domain
Blood Gas Analysis c
has range
float

bloodGasPHdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/bloodGasPH

The pH of the blood.
has domain
Blood Gas Analysis c
has range
float

bloodGasPO2dp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/bloodGasPO2

The level of PO2 in the blood.
has domain
Blood Gas Analysis c
has range
float

bloodGasSO2dp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/bloodGasSO2

The level of SO2 in the blood.
has domain
Blood Gas Analysis c
has range
float

bodyMassIndexdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bodyMassIndex

Weight in kilograms divided by the square of the height in metres, used esp. as an indicator of obesity or general nutritional status; also called Quetelet index; abbreviated BMI. [Definition Source: Oxford English Dictionary]

has characteristics: functional

has domain
Clinical Evaluation c
has range
float

bowelAndBladderEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bowelAndBladderEDSS

Expanded Disability Status Score (EDSS) score for bowel and bladder functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

bowelAndBladderRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bowelAndBladderRelapse

Whether the relapse involved bowel and bladder functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

brainAtrophyMRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/brainAtrophyMRI

The level of brain atrophy (cerebral atrophy) found in the brain of the patient shown by the MRI.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
{ "high" , "mild" , "moderate" , "none" }

brainstemEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/brainstemEDSS

Expanded Disability Status Score (EDSS) score for brainstem functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

brainstemRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/brainsetmRelapse

Whether the relapse involved the brainstem functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

bulbarOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bulbarOnset

Whether the patient experienced bulbar onset, which means he or she first notice speech or swallowing problems. [Definition Source: National Institute of Neurological Disorders and Stroke]

has characteristics: functional

has domain
Onset c
has range
boolean

bulbarSubscoredp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/bulbarSubscore

Bulbar ALSFRS subscore. Sum of items: 1, 2 and 3.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

cardiacDiseasedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cardiacDisease

Whether a patient ever had a cardiac disease.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

cerebellarEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cerebellarEDSS

Expanded Disability Status Score (EDSS) score for cerebellar functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

cerebellarRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cerebellarRelapse

Whether the relapse involved the celebellar functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

cerebralEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cerebralEDSS

Expanded Disability Status Score (EDSS) score for cerebral functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

cervicalSpineSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cervicalSpineSurgery

Whether a patient had a cervical spine surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

cervicalTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cervicalTrauma

Whether a patient had a cervical trauma.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

clinicallyEvaluatedEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/clinicallyEvaluatedEDSS

Expanded Disability Status Score (EDSS) evaluated by the physician.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
float

clinicalTrialDescriptiondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/clinicalTrialDescription

The description of a clinical trial.
has domain
Clinical Trial c
has range
plain literal

clusteringCoefficientdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/clusteringCoefficient

The coefficient of clustering for connectivity tests.
has domain
Cognitive Assessment c
has range
float

cognitiveRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/cognitiveRelapse

Whether the relapse involved the mental functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

comorbiditySeveritydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/comorbiditySeverity

The severity of a comorbidity.

has characteristics: functional

has domain
Comorbidity c
has range
{ "life risk" , "moderate" , "serious" , "slight" }

comorbidityTreatmentdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/comorbidityTreatment

The treatment used for the comorbidity.
has domain
Comorbidity c
has range
plain literal

componentNamedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/componentName

The name of the hematopoietic component tested in the laboratory test result.

has characteristics: functional

has domain
Laboratory Test Result c
has range
plain literal

concentrationMeasurementdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/concentrationMeasurement

Raw air pollution concentration measured by the Sensing Device.
has domain
air pollution concentration c
has range
float

conditionEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/conditionEnd

The calendar date of the end of the registered prexisting conditon.

has characteristics: functional

has domain
Conditon c
has range
date

conditionStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/conditionStart

The calendar date of the start of the registered prexisting conditon.

has characteristics: functional

has domain
Conditon c
has range
date

conductionBlocksdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/conductionBlocks

Presence of conduction blocks on electromyography.
has domain
Electromyography c
has range
boolean

contiguousLesionsMRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/contiguousLesionsMRI

Whether the MRI detected the presence of extended contiguous lesions equal to or greater than three vertical segments.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
boolean

dailyCigarettesdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/dailyCigarettes

The number of cigarettes smoked in one day on average.

has characteristics: functional

has domain
Smoking c
has range
integer

deathCausedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/deathCause

The circumstance or condition that results in the death of a living being. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
plain literal

deathDatedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/deathDate

The calendar date of subject's death. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
date

dextricitydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/dextricity

The preferred hand of use for controlled and efficient performance of motor tasks. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
integer

diabetesdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/diabetes

Whether a patient ever had diabetes.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

diagnosticCriteriadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/diagnosticCriteria

A standard from which a judgment concerning a medical diagnosis can be established. [Definition Source: NCI]

has characteristics: functional

has domain
Diagnosis c
has range
plain literal

dietdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/diet

Regular course of eating and drinking adopted by a person or animal. [Definition Source: MSH]

has characteristics: functional

has domain
Lifestyle c
has range
plain literal

dyslipidemiadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/dyslipidemia

Whether a patient ever had dyslipidemia.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

educationLeveldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/educationLevel

An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
plain literal

electricTraumaRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/electricTraumaRisk

Risk factor associated to electric trauma.
has domain
Risk Factor c
has range
boolean

electromyographyOutcomedp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/electromyographyOutcome

The outcome of the electromyography test.
has domain
Electromyography c
has range
plain literal

emotionalLiabilitydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/emotionalLiability

Boolean data property stating whether the patient experienced emotionalliability during the visit.
has domain
Clinical Evaluation c
has range
boolean

endReasondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/endReason

The reason for the interruption of the subject's participation in a clinical trial.
has domain
Clinical Trial Participation c
has range
plain literal

endTherapyReasondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/endTherapyReason

The reason for the interruption of the therapeutic treatment.

has characteristics: functional

has domain
End Therapy Reason c
has range
plain literal

eventEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/eventEnd

The calendar date of the end of the event.

has characteristics: functional

has domain
Event c
has range
date

eventStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/eventStart

The calendar date of the start of the event.

has characteristics: functional

has domain
Event c
has range
date

everSmokeddp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/everSmoked

Whether a patient has ever smoked.
has domain
Patient c
has range
boolean

evokedPotentialsLocationdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/evokedPotentialsLocation

The body location of the evoked potential test.

has characteristics: functional

has domain
Evoked Potentials c
has range
{ "left" , "lower" , "lower left" , "lower right" , "right" , "upper" , "upper left" , "upper right" }

evokedPotentialsResponsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/evokedPotentialsResponse

The evoked potential function test result.

has characteristics: functional

has domain
Evoked Potentials c
has range
{ "altered" , "normal" }

evokedPotentialsTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/evokedPotentialsType

Whether the test was a Visual Evoked Potential (VEP), Auditory Evoked Potential (AEP), Somatosensory Evoked Potential (SSEP) or Motor Evoked Potential (MEP).

has characteristics: functional

has domain
Evoked Potentials c
has range
{ "auditory" , "motor" , "somatosensory" , "visual" }

formatDKEFSdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/formatDKEFS

The format of the Delis-Kaplan Executive Function System (D-KEFS)
has domain
Delis-Kaplan Executive Function System (D-KEFS) c
has range
plain literal

furtherRelapseBeforePLdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/furtherRelapseBeforePL

Further relapse before plasmapheresis (PL): A treatment that removes harmful antibodies from the blood.
has domain
Relapse c
has range
boolean

gadoliniumLesionsT1MRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/gadoliniumLesionsT1MRI

Whether the MRI detected some gadolinium-enhanced lesions in T1.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
boolean

gadoliniumLesionsT1MRINumberdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/gadoliniumLesionsT1MRINumber

The number of gadolinium-enhanced lesions in T1.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
integer

generalizedOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/generalizedOnset

Whether the patient experienced generalized onset, that are widespread symptoms.

has characteristics: functional

has domain
Onset c
has range
boolean

genomeSequencingdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/genomeSequencing

A procedure that can determine the DNA sequence for nearly the entire genome of an individual. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
plain literal

globalCoefficientdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/globalCoefficient

The global coefficient for connectivity tests.
has domain
Cognitive Assessment c
has range
float

glucoseCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/glucoseCSF

A quantitative measurement of blood sugar present in a sample of CSF. Unit of measure : [mg/l].

has characteristics: functional

has domain
CSF Analysis c
has range
float

granulocytesCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/granulocytesCSF

The percentage of granulocytes present in a sample of CSF. Unit of measure : [%].

has characteristics: functional

has domain
CSF Analysis c
has range
float

hadMajorTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hadMajorTrauma

Whether a patient had a major trauma before the disease onset.
has domain
Before Onset c
has range
boolean

hadSurgicalInterventiondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hadSurgicalIntervention

Whether the patient had a surgical intervention before the disease onset.
has domain
Before Onset c
has range
boolean

hasMutationdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hasMutation

Whether the gene tested positive or negative for mutations during genetic testing.

has characteristics: functional

has domain
Genetic Testing c
has range
boolean

headNeckSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/headNeckSurgery

Whether a patient had a surgery in the head and neck area.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

headTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/headTrauma

Whether a patient had an head trauma.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

heightdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/height

Distance or measurement from the base upwards; altitude; stature (of the human body). [Source: Oxford English Dictionary]

has characteristics: functional

has domain
Clinical Evaluation c
has range
float

herbicidesRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/herbicidesRisk

Risk factor associated to herbicides.
has domain
Risk Factor c
has range
boolean

hoffmanLeftdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/hoffmanLeft

Hoffman's Reflex on the left side.
has domain
Hoffman's Reflex Test c
has range
plain literal

hoffmanRightdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/hoffmanRight

Hoffman's Reflex on the right side.
has domain
Hoffman's Reflex Test c
has range
plain literal

hypertensiondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/hypertension

Whether a patient ever had hypertension.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

IgGIndexCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/IgGIndexCSF

The IgG index is the ratio of the quotients for IgG and albumin (IgGcsf/IgGs)/(Albcsf/Albs). It is a quantitative analysis of the relationship between CSF IgG and serum IgG, divided by the same relationship for albumin. [Definition Source: Simonsen, Cecilia Smith et al. “The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis.” Multiple sclerosis journal - experimental, translational and clinical vol. 6,1 2055217319901291. 22 Jan. 2020]

has characteristics: functional

has domain
CSF Analysis c
has range
float

immunoglobulinGCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/immunoglobulinGCSF

A quantitative measurement of Immunoglobulin G (IgG) present in a sample of CSF. Unit of measure : [mg/l].

has characteristics: functional

has domain
CSF Analysis c
has range
float

intensitydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/intensity

The level of intensity with which the physical activity is carried out.
has domain
Physical Activity c
has range
plain literal

kingsValuedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/kingsValue

The patient's disease stage according to the King's Staging System.

has characteristics: functional

has domain
King's Clinical Staging Method c
has range
integer

leftPlantarReflexdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/leftPlantarReflex

Cutaneous-Plantar Reflex of the left foot.
has domain
Plantar Reflex Test c
has range
plain literal

lesionsT1MRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/lesionsT1MRI

Whether the MRI detected some lesions in T!.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
boolean

leukocytesCountCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/leukocytesCountCSF

A quantitative measurement of leukocytes present in a sample of CSF. Unit of measure : [/mm3].

has characteristics: functional

has domain
CSF Analysis c
has range
float

limbsOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/limbsOnset

Whether the patient experienced limb onset, which menas symptoms began in the arms or legs. [Definition Source: National Institute of Neurological Disorders and Stroke]

has characteristics: functional

has domain
Onset c
has range
boolean

lowerLimbsTendonReflexdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/lowerLimbsTendonReflex

Tendon Reflex of the lower limbs
has domain
Tendon Reflex Test c
has range
plain literal

lowerLimbSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/lowerLimbSurgery

Whether a patient had a lower limb surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

lumboSacralSpineSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/lumboSacralSpineSurgery

Whether a patient had a lumbo sacral spine surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

lumboSacralTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/lumboSacralTrauma

Whether a patient had a lumbo sacral trauma.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

lymphocytesCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/lymphocytesCSF

The percentage of lymphocytes present in a sample of CSF. Unit of measure : [%].

has characteristics: functional

has domain
CSF Analysis c
has range
float

maritalStatusdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/maritalStatus

A demographic parameter indicating a person's current conjugal status. [Definition Source: NCI]

has characteristics: functional

has domain
Patient c
has range
plain literal

massetericReflexdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/massetericReflex

Clinical assessment of the masseteric reflex.
has domain
Clinical Evaluation c
has range
plain literal

measuredLeveldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/measuredLevel

The level of the hematopoietic component measured in the laboratory test result.

has characteristics: functional

has domain
Laboratory Test Result c
has range
float

measurementCalibrateddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/measurementCalibrated

Air pollution concentration value with seasonal components and noise removed.
has domain
air pollution concentration c
has range
float

menopauseStatusdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/menopauseStatus

An indicator as to whether the female subject is in menopause. [Defintion source: NCI]

has characteristics: functional

has domain
Patient c
has range
boolean

metalsRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/metalsRisk

Risk factor associated to metals.
has domain
Risk Factor c
has range
boolean

methodCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/methodCSF

CSF analysis method.
has domain
CSF Analysis c
has range
{ "Old" , "SEBIA" }

mitosValuedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/mitosValue

The patient's disease stage according to the MiToS staging system.

has characteristics: functional

has domain
Milano-Torino Functional Staging System (MiToS) c
has range
integer

moreThan10PercentWeightlossdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/moreThan10PercentWeightloss

Whether a patient lost more than 10% of his or her body weight.

has characteristics: functional

has domain
Clinical Evaluation c
has range
boolean

motorSubscoredp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/motorSubscore

Motor ALSFRS subscore. Sum of items: 4, 5, 6, 7, 8 and 9.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

msDiagnosis2010Criteriadp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/msDiagnosis2010Criteria

Diagnosis following 2010 criteria
has domain
Diagnosis c
has range
{ "Relapsing Remitting Multiple Sclerosis (RRMS)" }

MSInPaediatricAgedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/MSInPaediatricAge

An indicator of whether the patient contracted Multiple Sclerosis (MS) in paediatric age.

has characteristics: functional

has domain
Patient c
has range
boolean

multipleSclerosisTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/multipleSclerosisType

The Multiple Sclerosis (MS) disease course identified in the patient.

has characteristics: functional

has domain
Clinical Evaluation c
has range
{ "clinically isolated syndrome (CIS)" , "primary progressive MS (PP)" , "radiologically isolated syndrome (RIS)" , "relapsing-remitting MS (RR)" , "secondary progressive MS (SP)" }

muscleAtrophydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/muscleAtrophy

Clinical assessment of muscle atrophy.
has domain
Clinical Evaluation c
has range
plain literal

muscleBiopsyOutcomedp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/musculeBiopsyOutcome

Outcome of the muscle biopsy.
has domain
Muscle Biopsy c
has range
plain literal

muscleTonedp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/muscleTone

Clinical assessment of muscle tone.
has domain
Clinical Evaluation c
has range
plain literal

mutationTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/mutationType

The type of mutation observed in the gene during genetic testing.
has domain
Genetic Testing c
has range
plain literal

neckTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/neckTrauma

Whether a patient had a neck trauma.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

newOrEnlargedLesionsT2MRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/newOrEnlargedLesionsT2MRI

Whether the MRI detected new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
boolean

newOrEnlargedLesionsT2MRINumberdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/newOrEnlargedLesionsT2MRINumber

The number of new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
integer

normalLeveldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/normalLevel

Whether the measured level is within the normal range for the tested hematopoietic component.

has characteristics: functional

has domain
Laboratory Test Result c
has range
boolean

notesdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/notes

An open box for adding notes about the patient.
has domain
Patient c
has range
plain literal

oligoclonalBandsNumberdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsNumber

The number of oligoclonal bands present in the specimen.

has characteristics: functional

has domain
Oligoclonal Bands c
has range
integer

oligoclonalBandsPresencedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsPresence

Whether the tested specimen presents oligoclonal bands.

has characteristics: functional

has domain
Oligoclonal Bands c
has range
boolean

oligoclonalBandsTypedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/oligoclonalBandsType

Whether the oligoclonal bands were found in CSF or in CSF & serum.

has characteristics: functional

has domain
Oligoclonal Bands c
has range
{ "in CSF" , "in CSF & serum" }

onsetElapsedTimedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/onsetElapsedTime

The time elapsed since the occurrence of an event that happened before the onset.

has characteristics: functional

has domain
Before Onset c
has range
{ "beyond 5years" , "within 5 yeras" }

originalALSFRSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/originalALSFRS

Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items: 1,2,3,4,5,6,7,8,9 and old10.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

otherOnsetdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/otherOnset

Other symptoms experienced by the patient during onset.
has domain
Onset c
has range
plain literal

otherRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/otherRelapse

Other functional systems involved in the relapse.
has domain
Relapse c
has range
plain literal

packYeardp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/packYear

Quantificator of lifetime tobacco exposure defined as: (number of cigarettes smoked per day) X (number of years smoked)/20.

has characteristics: functional

has domain
Smoking c
has range
float

participationEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/participationEnd

The calendar date of the end of subject's partiicpation in a clinical trial.

has characteristics: functional

has domain
Clinical Trial Participation c
has range
date

participationStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/participationStart

The calendar date of the start of subject's partiicpation in a clinical trial.

has characteristics: functional

has domain
Clinical Trial Participation c
has range
date

pathologicalJCCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pathologicalJCCSF

Whether the JC virus detected in the CSF specimen is pathological.

has characteristics: functional

has domain
CSF Analysis c
has range
boolean

pelvicSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pelvicSurgery

Whether a patient had a pelivc surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

performedCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/performedCSF

Whether a CSF analysis was performed.
has domain
CSF Analysis c
has range
boolean

performedCSFAnalysisdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/performedCSFAnalysis

Whether the CSF analysis was performed.
has domain
CSF Analysis c
has range
boolean

performedMuscleBiopsydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/performedMuscleBiopsy

Whether the muscle biopsy was performed.
has domain
Muscle Biopsy c
has range
boolean

pesticidesRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/pesticidesRisk

Risk factor associated to pesticides.
has domain
Risk Factor c
has range
boolean

petOutcomedp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/petOutcome

The outcome of the PET scan.
has domain
Positron Emission Tomography (PET) c
has range
plain literal

placeAreadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/placeArea

The type of populated area that better describe the place.
has domain
Place c
has range
{ "city" , "rural" , "town" }

polioRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/polioRisk

Risk factor associated to poliomyelitis.
has domain
Risk Factor c
has range
boolean

positivityResultdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/positivityResult

Whether the laboratory test result was positive or not.

has characteristics: functional

has domain
Laboratory Test Result c
has range
boolean

predominantLimbsImpairmentdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/predominantLimbsImpairment

Whether the patient predominantly presents distal limbs impairment or proximal limbs impairment.

has characteristics: functional

has domain
Clinical Evaluation c
has range
{ "both" , "distal" , "proximal" }

predominantLimbsSidedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/predominantLimbsSide

The side of the body that predominantly presents limb impariment.

has characteristics: functional

has domain
Clinical Evaluation c
has range
{ "left" , "right" , "symmetric" }

predominantMotorNeurondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/predominantMotorNeuron

Whether the patient presents a predominance of lower motor neuron, upper motor neuron or both.

has characteristics: functional

has domain
Clinical Evaluation c
has range
{ "both motor neuron" , "lower motor neuron" , "upper motor neuron" }

pregnancyComplicationsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pregnancyComplications

Any kind of complication related to the pregnancy.
has domain
Pregnancy c
has range
plain literal

pregnancyEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pregnancyEnd

The calendar date in which the pregnancy ended.

has characteristics: functional

has domain
Pregnancy c
has range
date

pregnancyEndEventdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pregnancyEndEvent

The event that ended the pregnancy.

has characteristics: functional

has domain
Pregnancy c
has range
plain literal

pregnancyStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pregnancyStart

The calendar date in which the pregnancy started.

has characteristics: functional

has domain
Pregnancy c
has range
date

primaryNeoplasmdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/primaryNeoplasm

Whether a patient ever had a primary neoplasm.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

procedureEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/procedureEnd

The calendar date of the end of an intervention or procedure.

has characteristics: functional

has domain
Intervention or Procedure c
has range
date

procedureStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/procedureStart

The calendar start of an intervention or procedure.

has characteristics: functional

has domain
Intervention or Procedure c
has range
date

proteinsCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/proteinsCSF

A quantitative measurement of proteins present in a sample of CSF [ mg/l].

has characteristics: functional

has domain
CSF Analysis c
has range
float

pulmonaryAOPAbsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryAOPAbs

Occlusion pressure at 100 ms (P0.1) is defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit. [Definition Source: Beloncle, F., Piquilloud, L., Olivier, PY. et al. Accuracy of P0.1 measurements performed by ICU ventilators: a bench study. Ann. Intensive Care 9, 104 (2019)]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryFEV6dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryFEV6

Forced expiratory volume (FEV) is the amount of air expired in six seconds of the FVC test. [Definition Source: John Hopkins Medicine]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryFVCReldp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryFVCRel

The percentage of Forced vital capacity (FVC) is the amount of air exhaled forcefully and quickly after inhaling as much as you can. [Defintion Source: John Hopkins Medicine]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryMEPAbsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryMEPAbs

Maximum Expiratory Pressure (MEP) is the highest pressure that can be developed during a forceful expiratory effort against an occluded airway. It is usually measured at maximal inspiration and reported as a positive number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryMIPAbsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryMIPAbs

Maximum Inspiratory Pressure (MIP) is the lowest pressure developed during a forceful inspiration against an occluded airway. It is usually measured at maximal expiration and recorded as a negative number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryPCO2dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryPCO2

The partial pressure of carbon dioxide (PCO2) is the concentration of carbon dioxide in the blood. This is a sensitive indication of the efficiency or level of ventilation of the lungs. [Definition Source: Collins Dictionary of Medicine]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryPO2dp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryPO2

The partial pressure of oxigen (PO2) is the concentration of oxygen in the blood. This commonly measured parameter is an important indicator of the efficiency with which oxygen is transferred from atmosphere to blood. [Definition Source: Collins Dictionary of Medicine]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pulmonaryVCAbsdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pulmonaryVCAbs

Vital capacity (VC) is the total volume of air that can be exhaled after inhaling as much as you can. [Definition Source: John Hopkins Medicine]

has characteristics: functional

has domain
Pulmonary Function Test c
has range
float

pyramidalEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pyramidalEDSS

Expanded Disability Status Score (EDSS) score for pyramidal functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

pyramidalRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/pyramidalRelapse

Whether the relapse involved the pyramidal functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

Questionnaire's score reported by a patient.dp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/selfReportedScore

has domain
Multiple Scleroris Neuropsychological Questionnaire (MSNQ) c or Self-Reported Questionnaire c
has range
float

quotientAlbuminCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/quotientAlbuminCSF

CSF/serum albumin ratio is performed to understand the blood–CSF barrier disruption. [Defintion Source: Luque, Francisco A, and Stephen L Jaffe. “Cerebrospinal fluid analysis in multiple sclerosis.” International review of neurobiology vol. 79 (2007)]

has characteristics: functional

has domain
CSF Analysis c
has range
float

raoClassificationdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/raoClassification

Rao's classification divides lesions into four types: • Type I: Hyperintense lesions only on T2. • Type II: Lesions isointense on T1, hyperintense on T2, without enhancement. • Type III: Lesions isointense on T1, hyperintense on T2, with incomplete enhancement in the shape of an open ring. • Type IV: Lesions isointense on T1, hyperintense on T2, with complete enhancement in the shape of a closed ring.
has domain
Clinical Evaluation c
has range
plain literal

relapseClinicalTherapydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseClinicalTherapy

Whether the relapse required treatment in an ambulatory care clinic.

has characteristics: functional

has domain
Relapse c
has range
boolean

relapseCortisoneTherapydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseCortisoneTherapy

Whether the relapse required a cortisone therapy.

has characteristics: functional

has domain
Relapse c
has range
boolean

relapseDurationdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseDuration

The number of days the relapse lasted.

has characteristics: functional

has domain
Relapse c
has range
integer

relapseEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseEnd

The calendar date of the end of the relapse.

has characteristics: functional

has domain
Relapse c
has range
date

relapseHospitalAdmissiondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseHospitalAdmission

Whether the relapse required an hospital admission.

has characteristics: functional

has domain
Relapse c
has range
boolean

relapseImpactOnADLdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseImpactOnADL

Whether the relapse afftecd the Activity of Daily Living (ADL).

has characteristics: functional

has domain
Relapse c
has range
boolean

relapseRecoverydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseRecovery

How much the patient recovered from the relapse.

has characteristics: functional

has domain
Relapse c
has range
{ "complete" , "none" , "partial" }

relapseSequeladp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseSequela

Whether the patient presented symptoms continuing in time, maybe less severe.

has characteristics: functional

has domain
Relapse c
has range
boolean

relapseSeveritydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseSeverity

The severity of the relapse.

has characteristics: functional

has domain
Relapse c
has range
{ "life risk" , "moderate" , "serious" , "slight" }

relapseStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/relapseStart

The calendar date of the start of the relapse.

has characteristics: functional

has domain
Relapse c
has range
date

residenceEnddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/residenceEnd

The calendar end date of the patient's residence in a specific geographical location.

has characteristics: functional

has domain
Residence c
has range
date

residenceStartdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/residenceStart

The calendar start date of the patient's residence in a specific geographical location.

has characteristics: functional

has domain
Residence c
has range
date

respiratorySubscoredp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/respiratorySubscore

Respiratory ALSFRS subscore. Sum of items: 10, 11 and 12.

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

retiredAtDiagnosisdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/retiredAtDiagnosis

An indicator of whether the patient was retired at the time of diagnosis.

has characteristics: functional

has domain
Patient c
has range
boolean

revisedALSFRSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/revisedALSFRS

Revised Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12.
Is defined by
http://purl.bioontology.org/ontology/SNOMEDCT/718646004

has characteristics: functional

has domain
Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) c
has range
integer

rightPlantarReflexdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/rightPlantarReflex

Cutaneous-Plantar Reflex of the right foot.
has domain
Plantar Reflex Test c
has range
plain literal

sensoryEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sensoryEDSS

Expanded Disability Status Score (EDSS) score for sensory functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

sensoryRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sensoryRelapse

Whether the relapse involved sensory functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

sexdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sex

The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. [Definition Source: NCI]

has characteristics: functional

has domain
Person c
has range
{ "female" , "male" }

sexualitydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sexuality

The feeling an individual has about their own sexual preferences and how those views are acted upon. [Definition Source: NCI]

has characteristics: functional

has domain
Lifestyle c
has range
plain literal

solventsRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/solventsRisk

Risk factor associated with solvents.
has domain
Risk Factor c
has range
boolean

sportRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/sportRisk

Risk factor associated to sport.
has domain
Risk Factor c
has range
boolean

strokedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/stroke

Whether a patient ever had a stroke.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

sunExposuredp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/sunExposure

The exposure to incident light from the sun. [Definition Source: NCI]

has characteristics: functional

has domain
Lifestyle c
has range
integer

thoracicSpineSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/thoracicSpineSurgery

Whether a patient had a thoracic spine surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

thoracicSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/thoracicSurgery

Whether a patient had a thoracic surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

thoracicTraumadp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/thoracicTrauma

Whether a patient had a thoracic trauma.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

thyroidDisorderdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/thyroidDisorder

Whether a patient ever had a thyroid disorder.
has domain
ALS Brainteaser Comorbidities c
has range
boolean

tongueAtrophydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/tongueAtrophy

Wasting of the tongue. [Definition Source: HPO]
has domain
Neurologic Exam c
has range
plain literal

tongueFasciculationdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/tongueFasciculation

Fasciculations or fibrillation affecting the tongue muscle. [Definition Source: HPO]
has domain
Neurologic Exam c
has range
plain literal

tongueNotProtrudingdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/tongueNotProtruding

Tongue not extending beyond the alveolar ridges or teeth at rest. [PMID:19125428]
has domain
Neurologic Exam c
has range
plain literal

tongueProtrusiondp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/tongueProtrusion

Tongue extending beyond the alveolar ridges or teeth at rest. [PMID:19125428]
has domain
Neurologic Exam c
has range
plain literal

tongueThrustdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/tongueThrust

Pressing forward of the tongue in the mouth, a retained motoric habit from infantile swallowing patterns [PMID:34413610]
has domain
Neurologic Exam c
has range
plain literal

totalLesionsT2MRIdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/totalLesionsT2MRI

The total number of lesions in T2 detected with the MRI.

has characteristics: functional

has domain
Magnetic Resonance Imaging (MRI) c
has range
plain literal

traumaDatedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/traumaDate

The calendar date in which the trauma occurred.

has characteristics: functional

has domain
Trauma c
has range
date

traumaDescriptiondp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/traumaDescription

A description of the trauma
has domain
Trauma c
has range
plain literal

traumaRiskdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/traumaRisk

Risk factor associated to trauma.
has domain
Risk Factor c
has range
boolean

unitOfMeasuredp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/unitOfMeasure

The unit of measure of reference of the laboratory test result.

has characteristics: functional

has domain
Laboratory Test Result c
has range
plain literal

upperLimbsMobilitydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/upperLimbsMobility

Clinical assessment of upper limbs mobility and coordination.
has domain
Clinical Evaluation c
has range
plain literal

upperLimbsTendonReflexdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/upperLimbsTendonReflex

Tendon Reflex test for the upper limbs.
has domain
Tendon Reflex Test c
has range
plain literal

upperLimbSurgerydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/upperLimbSurgery

Whether a patient had an upper limb surgery.
has domain
Last 5 Years Event c or More Than 5 Years Event c
has range
boolean

urinaryUrgencydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/urinaryUrgency

Boolean property stating whether the patient had urinary urgency during the visit.
has domain
Clinical Evaluation c
has range
boolean

urinaryUrgencyTherapydp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/urinaryUrgencyTherapy

Boolean property stating whether the patient follows urinary urgency therapy.
has domain
Clinical Evaluation c
has range
boolean

virusJCTestedCSFdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/virusJCTestedCSF

Whether the presence of JC virus was tested in the CSF specimen.

has characteristics: functional

has domain
CSF Analysis c
has range
boolean

visualEDSSdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/visualEDSS

Expanded Disability Status Score (EDSS) score for visual (optic) functions.

has characteristics: functional

has domain
Expanded Disability Status Scale (EDSS) c
has range
integer

visualEvokedPotentialAmplitudedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/visualEvokedPotentialAmplitude

The amplitude for the Visual Evoked Potential (VEP) wave. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [uV].

has characteristics: functional

has domain
Evoked Potentials c
has range
float

visualEvokedPotentialLatencydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/visualEvokedPotentialLatency

The average peak latency for the Visual Evoked Potential (VEP) wave at approximately 100 ms following stimulus onset. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [microsec].

has characteristics: functional

has domain
Evoked Potentials c
has range
integer

visualRelapsedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/visualRelapse

Whether the relapse involved visual functions.

has characteristics: functional

has domain
Relapse c
has range
boolean

walkEvaluationdp back to ToC or Data Property ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/walkEvaluation

Clinical assessment of walking ability.
has domain
Clinical Evaluation c
has range
plain literal

weeklyFrequencydp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/weeklyFrequency

The number of times per week physical activity takes place.
has domain
Physical Activity c
has range
integer

weightdp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/weight

Measurement of quantity by means of weighing; quantity (in the abstract) as determined in this way. [Definition Source: Oxford English Dictionary]

has characteristics: functional

has domain
Clinical Evaluation c
has range
float

zipCodedp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/zipCode

A group of letters or numbers, or both, added to a postal address to facilitate the sorting and delivery of mail. Later also: the area designated by such a code. [Definition Source: Oxford English Dictionary]

has characteristics: functional

has domain
Place c
has range
plain literal

zipHasheddp back to ToC or Data Property ToC

IRI: https://w3id.org/brainteaser/ontology/schema/zipHashed

The zip code hashed for privacy reasons.

has characteristics: functional

has domain
Place c
has range
plain literal

Named Individuals

Abdomenni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12664

The cavity located between the lungs and pelvis. It contains the lower esophagus, stomach, pancreas, intestines, liver, gallbladder and spleen. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Abdominal Painni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26682

Painful sensation in the abdominal region. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Abdominoplastyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/177250006

Surgical removal of excess abdominal skin and fat and tightening of the ABDOMINAL WALL. Abdominoplasty may include LIPECTOMY of INTRA-ABDOMINAL FAT, tightening of the ABDOMINAL MUSCLES, and re-creation of the UMBILICUS. [Definition Source: MSH]
belongs to
concept
Surgical Procedure Type c

ACE Inhibitors, Plainni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09AA

belongs to
concept
Pharmacologic Substance c

Acetylcarnitineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06BX12

belongs to
concept
Pharmacologic Substance c

Acetylsalicylic Acid, Combinations excl. Psycholepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02BA51

belongs to
concept
Pharmacologic Substance c

Aciclovirni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J05AB01

belongs to
concept
Pharmacologic Substance c

Acquired Hypothyroidismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C129644

Hypothyroidism, the cause of which is not present at birth. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Acute Cystitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26934

An acute infection of the bladder. It is usually caused by bacteria. Signs and symptoms include increased frequency of urination, pain or burning during urination, fever, cloudy or bloody urine, and suprapubic pain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Acute Myocardial Infarctionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35204

Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Acute Pyelonephritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C123215

Sudden onset pyelonephritis. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Acute Respiratory Failureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27043

Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Acute Tonsillitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C97142

An acute inflammation of the tonsils caused by viruses or bacteria. Signs and symptoms include fever, enlargement of the tonsils, difficulty swallowing, and enlargement of the regional lymph nodes. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ademetionineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A16AA02

belongs to
concept
Pharmacologic Substance c

Adenocarcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2852

A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Administration of Ineffective Drugni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000220

An errored drug administration where a patient is administered with an ineffective drug. [Definition Source: OAE]
belongs to
concept
Adverse Drug Reaction c

Administrative and commercial managersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C12

Administrative and commercial managers plan, organize, direct, control and coordinate the financial, administrative, human resource, policy, planning, research and development, advertising, public relations, and sales and marketing activities of enterprises and organizations, or of enterprises that provide such services to other enterprises and organizations. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level Tasks performed by workers in this sub-major group usually include: formulating and administering policy advice and strategic and financial planning; establishing and directing operational and administrative procedures; implementing, monitoring and evaluating strategies and policies; providing advice to senior managers; directing the development of initiatives for new products, marketing, public relations and advertising campaigns; determining and directing sales activities, product mix and customer service standards; setting prices and credit arrangements; ensuring compliance with relevant legislation, regulations and standards; controlling selection, training and performance of staff; preparing budgets and overseeing financial operations; consulting with the chief executive and with managers of other departments or sections; controlling expenditure and ensuring the efficient use of resources; representing the enterprise or organization in negotiations, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 121 Business Services and Administration Managers 122 Sales, Marketing and Development Managers
belongs to
concept
Occupation c

Adverse Drug Eventni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000005

An adverse event that occurs after a drug administration. [Definition Source: OAE]
belongs to
concept
Adverse Drug Reaction c

Adverse Drug Reactionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C142385

Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCIT] The taxonomy is based on OAE.
belongs to
concept scheme

Agents Acting on the Renin-Angiotensin Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09

belongs to
concept
Pharmacologic Substance c

Ageusiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C116374

Inability to taste. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Agricultural, forestry and fishery labourersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C92

Agricultural, forestry and fishery labourers perform simple and routine tasks in the production of crops and livestock, cultivation and maintenance of gardens and parks, exploitation and conservation of forests, and conduct of aquaculture and fisheries operations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: digging, raking and shovelling using hand tools; loading, unloading and stacking supplies, produce and other materials; watering, thinning, weeding and tending crops by hand or using hand tools; planting, harvesting, picking and collecting produce by hand; feeding, watering and cleaning animals and keeping their quarters clean; monitoring livestock and reporting on their condition; preparing and operating nets, lines and other fishing tackle and deck equipment; grading, sorting, bunching and packing produce into containers; performing minor repairs on fixtures, buildings, equipment, vessels and fences. Occupations in this sub-major group are classified into the following minor group: 921 Agricultural, Forestry and Fishery Labourers
belongs to
concept
Occupation c

Alanine Aminotransferase Increasedni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26948

An increase in the level of alanine aminotransferase in the blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Alcohol Dependanceni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C93040

Physical and psychological dependence on alcohol. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Alectinibni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01ED03

belongs to
concept
Pharmacologic Substance c

Alemtuzumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA34

belongs to
concept
Pharmacologic Substance c

Alimentary Tract and Metabolismni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A

belongs to
concept
Pharmacologic Substance c

All Other Non-Therapeutic Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V07

belongs to
concept
Pharmacologic Substance c

All Other Therapeutic Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V03

belongs to
concept
Pharmacologic Substance c

Allergensni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V01

belongs to
concept
Pharmacologic Substance c

Allergic Asthmani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/389145006

Allergic Asthma
belongs to
concept
Disease, Disorder or Finding c

Allergic Rhinitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C79532

Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Alpha-Lipoic Acidni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C61595

A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. [Definition Source: NCI]
belongs to
concept
Pharmacologic Substance c

Alprazolamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA12

belongs to
concept
Pharmacologic Substance c

Alzheimer's Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2866

A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Amantadineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04BB01

belongs to
concept
Pharmacologic Substance c

Amenorrheani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C61443

The absence of menses in a woman who has achieved reproductive age. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Amenorrhea due to Pituitary Dysfunctionni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/1144987003

The absence of menses in a woman who has achieved reproductive age due to disorder of pituitary gland. [Partial Defintion Source: NCI
belongs to
concept
Disease, Disorder or Finding c

Amiodaroneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C01BD01

belongs to
concept
Pharmacologic Substance c

Amitriptylineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AA09

belongs to
concept
Pharmacologic Substance c

Amitriptyline and Psycholepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06CA01

belongs to
concept
Pharmacologic Substance c

Amlodipineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C08CA01

belongs to
concept
Pharmacologic Substance c

Amoxicillin and Beta-Lactamase Inhibitorni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J01CR02

belongs to
concept
Pharmacologic Substance c

Amyotrophic Lateral Sclerosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34373

A neurodegenerative disorder characterized by progressive degeneration of the motor neurons of the central nervous system. It results in weakness and atrophy of the muscles which leads to an inability to initiate and control voluntary movements. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anabolic Agents for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A14

belongs to
concept
Pharmacologic Substance c

Analgesicsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02

belongs to
concept
Pharmacologic Substance c

Anatomic Siteni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C13717

Named locations of or within the body. [Definition Source: NCIT] The taxnomy is mainly based on NCIT.
belongs to
concept scheme

Anemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2869

A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anestheticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N01

belongs to
concept
Pharmacologic Substance c

Angioedemani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112175

Rapid swelling of the deep layers of the skin due to transient vascular leakage of serous fluid. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Ankle Fractureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26989

Traumatic or pathological injury to the ankle joint in which the continuity of an ankle bone is broken. Symptoms include pain, swelling, and difficulty moving the affected leg and foot. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ann Arbor Stage IV Mantle Cell Lymphomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C8486

Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C8668

Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anorectal Fistulani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C60785

A pathologic tract that connects an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anorexiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2875

Loss of appetite. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anosmiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C116369

Inability to smell. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Anthelminticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/P02

belongs to
concept
Pharmacologic Substance c

Anti-Acne Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D10

belongs to
concept
Pharmacologic Substance c

Anti-Parkinson Drugsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04

belongs to
concept
Pharmacologic Substance c

Antianemic Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B03

belongs to
concept
Pharmacologic Substance c

Antibacterials for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J01

belongs to
concept
Pharmacologic Substance c

Antibiotics and Chemotherapeutics for Dermatological Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D06

belongs to
concept
Pharmacologic Substance c

Anticonvulsant Agentni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C264

Medicine to stop, prevent, or control seizures (convulsions). [Definition Source: NCI]
belongs to
concept
Therapeutic Procedure Type c

Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A07

belongs to
concept
Pharmacologic Substance c

Antiemetics and Antinauseantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A04

belongs to
concept
Pharmacologic Substance c

Antiepilepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03

belongs to
concept
Pharmacologic Substance c

Antifungals for Dermatological Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D01

belongs to
concept
Pharmacologic Substance c

Antigout Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M04

belongs to
concept
Pharmacologic Substance c

Antihemorrhagicsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B02

belongs to
concept
Pharmacologic Substance c

Antihistamines for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R06

belongs to
concept
Pharmacologic Substance c

Antihypertensivesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C02

belongs to
concept
Pharmacologic Substance c

Antiinfectives for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J

belongs to
concept
Pharmacologic Substance c

Antiinflammatory and Antirheumatic Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M01

belongs to
concept
Pharmacologic Substance c

Antimycobacterialsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J04

belongs to
concept
Pharmacologic Substance c

Antimycotics for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J02

belongs to
concept
Pharmacologic Substance c

Antineoplastic Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01

belongs to
concept
Pharmacologic Substance c

Antineoplastic and Immunomodulating Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L

belongs to
concept
Pharmacologic Substance c

Antiobesity Preparations, excl. Diet Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A08

belongs to
concept
Pharmacologic Substance c

Antiparasitic Products, Insecticides and Repellentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/P

belongs to
concept
Pharmacologic Substance c

Antiprotozoalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/P01

belongs to
concept
Pharmacologic Substance c

Antipruritics, incl. Antihistamines, Anesthetics, etc.ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D04

belongs to
concept
Pharmacologic Substance c

Antipsoriaticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D05

belongs to
concept
Pharmacologic Substance c

Antispetic and Disinfectantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D08

belongs to
concept
Pharmacologic Substance c

Antithrombotic Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01

belongs to
concept
Pharmacologic Substance c

Antivirals for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J05

belongs to
concept
Pharmacologic Substance c

Anxiety Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2878

A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Appendectomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/80146002

Surgical removal of the vermiform appendix. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Appetite Stimulantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A15

belongs to
concept
Pharmacologic Substance c

AR Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28539

This gene plays a role in the transcriptional activation of androgen responsive genes. [Definition Source: NCI]
belongs to
concept
Gene c

Armed forces occupationsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C0

Armed forces occupations include all jobs held by members of the armed forces. Members of the armed forces are those personnel who are currently serving in the armed forces, including auxiliary services, whether on a voluntary or compulsory basis, and who are not free to accept civilian employment and are subject to military discipline. Included are regular members of the army, navy, air force and other military services, as well as conscripts enrolled for military training or other service for a specified period. Occupations in this major group are classified into the following sub-major groups: 01 Commissioned Armed Forces Officers 02 Non-commissioned Armed Forces Officers 03 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
belongs to
concept
Occupation c

Armed forces occupations, other ranksni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C03

Armed forces occupations, other ranks include all conscripted and non-conscripted members of the armed forces except commissioned and non-commissioned officers. They perform specific military tasks and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. Most occupations in this sub-major group require skills at the first ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 031 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
belongs to
concept
Occupation c

Arrhythmiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2881

Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Arthritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2883

An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Asian (ethnic group)ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/315280000

A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (OMB) [Definition Source: NCI]
belongs to
concept
Group (social concept) c

Aspiration Pneumonitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34932

Inflammation of the lungs due to the inhalation of solid or liquid material. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Assemblersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C82

Assemblers assemble prefabricated parts or components to form subassemblies, products and equipment, according to procedures strictly laid down. The products worked on may be moved from one worker to the next along assembly lines. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assembling components into various types of product and equipment, according to strictly laid down procedures; reviewing work orders, specifications, diagrams and drawings to determine materials needed and assembly instructions; recording production and operational data on specified forms; inspecting and testing completed components and assemblies, wiring installations and circuits; rejecting faulty assemblies and components. Occupations in this sub-major group are classified into the following minor group: 821 Assemblers
belongs to
concept
Occupation c

Asthmani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28397

A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Atenololni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07AB03

belongs to
concept
Pharmacologic Substance c

Atenolol and Other Diureticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07CB03

belongs to
concept
Pharmacologic Substance c

Atopic Dermatitisni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/24079001

A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. [Definition Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Atrial Fibrillationni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50466

A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC) [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Atrial Flutterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C51224

A disorder characterized by an electrocardiographic finding of an organized, regular atrial rhythm with atrial rate of 240-340 beats per minute. Multiple P waves typically appear in the inferior leads in a saw tooth-like pattern between the QRS complexes. (CDISC) [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Atrovastatinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C10AA05

belongs to
concept
Pharmacologic Substance c

Auntni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96569

A female relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

Autoimmune Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2889

A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Autoimmune Nervous System Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C99383

A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Autoimmune Pancytopeniani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/183005

The autoimmune inability of the bone marrow to produce hematopoietic elements. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Azathioprineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AX01

belongs to
concept
Pharmacologic Substance c

Baclofenni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M03BX01

belongs to
concept
Pharmacologic Substance c

Bacterial Pneumoniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26704

Acute infection of the lung parenchyma caused by bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila). Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Baker Cystni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34935

Swelling and protrusion of the gastrocnemius-semimembranosus bursa due to an accumulation of synovial fluid. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Barbexacloneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AA04

belongs to
concept
Pharmacologic Substance c

Barnidipineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C08CA12

belongs to
concept
Pharmacologic Substance c

Basal Cell Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C156767

A carcinoma involving the basal cells. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

BCG Vaccineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AX03

belongs to
concept
Pharmacologic Substance c

Behavioral Impairmentni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/BehavioralImpairment

Diminished psychological function.
belongs to
concept
Disease, Disorder or Finding c

Bell's Palsyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/193093009

A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376) [Defintion Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Beta Blocking Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07

belongs to
concept
Pharmacologic Substance c

Betahistineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07CA01

belongs to
concept
Pharmacologic Substance c

Betamethasoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB01

belongs to
concept
Pharmacologic Substance c

BG-12ni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/N07XX09

belongs to
concept
Pharmacologic Substance c

Bile and Liver Therapy Drugsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A05

belongs to
concept
Pharmacologic Substance c

Bile Therapyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A05A

belongs to
concept
Pharmacologic Substance c

Biotinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A11HA05

belongs to
concept
Pharmacologic Substance c

Bipolar Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34423

A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Bisoprololni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07AB07

belongs to
concept
Pharmacologic Substance c

Black (ethnic group)ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/315240009

A person having origins in the original peoples of sub-Saharan Africa or the Caribbean.
belongs to
concept
Group (social concept) c

Black Africanni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/18167009

Denotes a person with ancestral origins are in any of the countries of Africa. [Definition Source: NCI]
belongs to
concept

Blepharititsni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112183

Inflammation of the eyelids near the eyelashes. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Blepharospasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C118723

Involuntary twitching of the eyelid. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Blood and Blood Forming Organsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B

belongs to
concept
Pharmacologic Substance c

Blood Substitutes and Perfusion Solutionsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B05

belongs to
concept
Pharmacologic Substance c

Bone Marrowni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12431

The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Botulinum Toxinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M03AX01

belongs to
concept
Pharmacologic Substance c

Bowel Obstructionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C9175

Blockage of the normal flow of the intestinal contents within the bowel. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Bradycardiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C37920

An abnormally slow heart rate. Thresholds for different age, gender, and patient populations exist. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Brainni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12439

An organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Brain Stemni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12441

Three sections, the midbrain, pons and medulla oblongata, that are located at the base of the brain. The brain stem regulates the central nervous system, and is vital as a conduit for motor and sensory innervations. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Breast Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4872

A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Bromazepamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA08

belongs to
concept
Pharmacologic Substance c

Brotherni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C111201

A male who shares with his sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]
belongs to
concept
KinshipType c

Brotizolamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05CD09

belongs to
concept
Pharmacologic Substance c

Brown-Sequard Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84601

A disorder caused by a spinal injury leading to an incomplete spinal lesion. Patients develop paralysis, ataxia and loss of sensation. Causes include spinal cord tumors, spinal traumas, ischemia, and inflammatory processes affecting the spine. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Building and related trades workers, excluding electriciansni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C71

Building and related trades workers construct, maintain and repair buildings; erect and repair foundations, walls and structures of brick, stone and similar materials; shape and finish stone for building and other purposes. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, the materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: constructing, maintaining and repairing buildings and other structures, using traditional and/or modern building techniques; constructing and repairing foundations, walls and structures of brick, stone and similar materials; breaking quarried stone into slabs or blocks; cutting, shaping and finishing stone for building, ornamental, monumental and other purposes; erecting reinforced concrete frameworks and structures as well as finishing and repairing cement surfaces; cutting, shaping, assembling and maintaining wooden structures and fittings; performing miscellaneous construction and building maintenance tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 711 Building Frame and Related Trades Workers 712 Building Finishers and Related Trades Workers 713 Painters, Building Structure Cleaners and Related Trades Workers
belongs to
concept
Occupation c

Business and administration associate professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C33

Business and administration associate professionals perform mostly technical tasks connected with the practical application of knowledge relating to financial accounting and transaction matters, mathematical calculations, human resource development, selling and buying financial instruments, specialized secretarial tasks, and enforcing or applying government rules. Also included are workers who provide business services such as customs clearance, conference planning, job placements, buying and selling real estate or bulk commodities, and serving as agents for performers such as athletes and artists. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include recording and transmitting buy and sell orders for securities, stocks, bonds or other financial instruments and for foreign exchange for future or immediate delivery; submitting credit and loan applications to management with recommendations for approval or rejection; approving or rejecting applications within authorized limits ensuring that credit standards of the institution are respected; maintaining complete records of all financial transactions of an undertaking according to general bookkeeping principles, with guidance from accountants; assisting in planning and performing mathematical, statistical, actuarial, accounting and related calculations; selling and buying financial instruments. Occupations in this sub-major group are classified into the following minor groups: 331 Financial and Mathematical Associate Professionals 332 Sales and Purchasing Agents and Brokers 333 Business Services Agents 334 Administrative and Specialized Secretaries 335 Government Regulatory Associate Professionals
belongs to
concept
Occupation c

Business and administration professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C24

Business and administration professionals perform analytical, conceptual and practical tasks to provide services in financial matters, human resource development, public relations, marketing and sales in the technical, medical, information and communications technology areas; and conduct reviews of organizational structures, methods and systems as well as quantitative analyses of information affecting investment programmes. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, analysing and interpreting information on the financial viability, cost structures and trading effectiveness of organizations; conducting audits, preparing financial statements and controlling treasury systems for organizations; developing and reviewing financial plans and strategies, executing buy and sell orders, and negotiating the purchase and sale of commodities; developing, implementing and evaluating staff recruitment, training and development programmes; researching, developing and implementing marketing and public relations campaigns; studying and developing methods and policies to improve and promote government and business operations and effectiveness; acquiring and updating knowledge of employers’ and competitors’ goods and services, and of market conditions; assessing customers’ needs and explaining and demonstrating goods and services to them. Occupations in this sub-major group are classified into the following minor group: 241 Finance Professionals 242 Administration Professionals 243 Sales, Marketing and Public Relations Professionals
belongs to
concept
Occupation c

C9orf72 Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C101398

This gene may play a role in cell death. [Definition Source: NCI]
belongs to
concept
Gene c

Cabergolineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04BC06

belongs to
concept
Pharmacologic Substance c

Calcifediolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A11CC06

belongs to
concept
Pharmacologic Substance c

Calcium Channel Blockersni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C08

belongs to
concept
Pharmacologic Substance c

Calcium Folinateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V03AF03

belongs to
concept
Pharmacologic Substance c

Calcium Homeostasisni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H05

belongs to
concept
Pharmacologic Substance c

Calcium, Combinations with Vitamin D and/or Other Drugsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A12AX

belongs to
concept
Pharmacologic Substance c

Cannabinoidsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02BG10

belongs to
concept
Pharmacologic Substance c

Carbamazepineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AF01

belongs to
concept
Pharmacologic Substance c

Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2916

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cardiac Therapyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C01

belongs to
concept
Pharmacologic Substance c

Cardiovascular Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2931

A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cardiovascular Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C

belongs to
concept
Pharmacologic Substance c

Cardioversionni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/250980009

The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one, by pharmacologic means using medications or by electrical cardioversion using a defibrillator. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Caucasianni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/14045001

A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. (OMB) [Definition Source: NCI]
belongs to
concept
Group (social concept) c

Cavernous Hemangiomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3086

A hemangioma characterized by the presence of cavernous vascular spaces. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ceftriaxoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J01DD04

belongs to
concept
Pharmacologic Substance c

Celiac Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26714

An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Central Nervous System Degenerative Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4802

A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cerebellumni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12445

The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Cervical Spinal Cordni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12892

The portion of the spinal cord located in the cervical region. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Cervical Spineni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C69313

The set of vertebrae immediately caudal to the skull. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Cetirizineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R06AE07

belongs to
concept
Pharmacologic Substance c

Chalazionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26717

An eyelid cyst caused by the blockage of a meibomian gland. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Chicken Poxni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C97132

A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Chief executives, senior officials and legislatorsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C11

Chief executives, senior officials and legislators formulate and review the policies, and plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations with the support of other managers. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level . Tasks performed by workers in this sub-major group usually include: presiding over or participating in the proceedings of legislative bodies, boards of directors and committees; formulating and advising on the policy budgets, laws and regulations of enterprises, governments and other organizations; establishing objectives for enterprises, government departments or agencies and other organizations; formulating or approving and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise; selecting or approving the selection of senior staff; performing ceremonial duties and representing the enterprise, government, organization or community at official occasions and in meetings, negotiations, conventions and public hearings. Occupations in this sub-major group are classified into the following minor groups: 111 Legislators and Senior Officials 112 Managing Directors and Chief Executives
belongs to
concept
Occupation c

Chlorphenamineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R06AB04

belongs to
concept
Pharmacologic Substance c

Cholecystectomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/38102005

Surgical removal of the gallbladder. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Chronic Atropic Gastritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C7405

Atrophic gastritis that is persistent and long-standing. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Chronic Lung Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C98541

A persistent non-neoplastic disorder of the lungs. Representative examples include: chronic obstructive pulmonary disease, chronic bronchitis, emphysema, pulmonary fibrosis, pneumoconiosis, asbestosis, atelectasis, radiation induced pneumonitis, and radiation fibrosis. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cinnarizineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07CA02

belongs to
concept
Pharmacologic Substance c

Cinnarizine, Combinationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07CA52

belongs to
concept
Pharmacologic Substance c

Citalopramni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AB04

belongs to
concept
Pharmacologic Substance c

Cladribineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01BB04

belongs to
concept
Pharmacologic Substance c

Cladribineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA40

belongs to
concept
Pharmacologic Substance c

Cleaners and helpersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C91

Cleaners and helpers perform various tasks in private households, hotels, offices, hospitals and other establishments, as well as in aircraft, trains, coaches, trams and similar vehicles, in order to keep the interiors and fixtures clean, and launder and press garments and textiles by hand. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: sweeping or vacuum cleaning; washing and polishing floors, furniture and other objects; taking care of linen and bedmaking; helping with preparation of meals and cleaning in kitchens; washing and cleaning cars and windows; pressing or laundering garments and textiles by hand. Occupations in this sub-major group are classified into the following minor groups: 911 Domestic, Hotel and Office Cleaners and Helpers 912 Vehicle, Window, Laundry and Other Hand Cleaning Workers
belongs to
concept
Occupation c

Cleft Palateni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C87069

A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Clerical support workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C4

Clerical support workers record, organize, store, compute and retrieve information, and perform a number of clerical duties in connection with money-handling operations, travel arrangements, requests for information, and appointments. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by clerical support workers usually include: stenography, typing, and operating word processors and other office machines; entering data into computers; carrying out secretarial duties; recording and computing numerical data; keeping records relating to stocks, production and transport; keeping records relating to passenger and freight transport; carrying out clerical duties in libraries; filing documents; carrying out duties in connection with mail services; preparing and checking material for printing; assisting persons who cannot read or write with correspondence; performing money-handling operations; dealing with travel arrangements; supplying information requested by clients and making appointments; operating a telephone switchboard. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 41 General and Keyboard Clerks 42 Customer Services Clerks 43 Numerical and Material Recording Clerks 44 Other Clerical Support Workers
belongs to
concept
Occupation c

Clobazamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA09

belongs to
concept
Pharmacologic Substance c

Clonazepamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AE01

belongs to
concept
Pharmacologic Substance c

Clopidogrelni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01AC04

belongs to
concept
Pharmacologic Substance c

Closed Dislocation of Shoulderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34486

A closed dislocation of the shoulder [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Closed Fracture of Ribni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35350

A traumatic break in one of the bones in the rib cage that does not involve a break in the adjacent skin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Closed Fracture of Tibiani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/447139008

A closed fracture of the tibia.
belongs to
concept
Disease, Disorder or Finding c

Codeine, Combinations excl. Psycholepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02AA59

belongs to
concept
Pharmacologic Substance c

Cognitive Imparimentni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C116921

Diminished mental function. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cold Soreni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34695

A lesion caused by type 1 or type 2 herpes simplex virus, involving the oralfacial region. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Colecalciferolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A11CC05

belongs to
concept
Pharmacologic Substance c

Colon Adenocarcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4349

An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Commissioned armed forces officersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C01

Commissioned armed forces officers provide leadership and management to organizational units in the armed forces and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes all members of the armed forces holding the rank of second lieutenant (or equivalent) or higher. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 011 Commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
belongs to
concept
Occupation c

Common Bile Duct Stoneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34499

The presence of one or more stones in the common bile duct. They are composed either of cholesterol or, less commonly, calcium salts and bilirubin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cone Biopsyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/110469002

The excision of a cone of tissue, especially of the CERVIX UTERI. [Definition Source: MSH]
belongs to
concept
Surgical Procedure Type c

Congenital Adrenal Hyperplasiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34360

A genetic disorder characterized by defects in the synthesis of cortisol and/or aldosterone, resulting in hyperplasia of the adrenal cortical cells. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Contrast Mediani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V08

belongs to
concept
Pharmacologic Substance c

Coronary Artery Bypass Graftni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/232717009

Surgery performed to bypass partially or completely occluded coronary arteries, thereby increasing the blood supply of the heart. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Corticosteroids for Systemic Useni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02

belongs to
concept
Pharmacologic Substance c

Corticosteroids, Dermatological Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D07

belongs to
concept
Pharmacologic Substance c

Corticotropinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H01AA01

belongs to
concept
Pharmacologic Substance c

Cortisone Therapy for Relapseni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/CortisoneTherapyForRelapse

Therapy based on cortisone used for treating relapses.
belongs to
concept
Therapeutic Procedure Type c

Cough and Cold Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R05

belongs to
concept
Pharmacologic Substance c

Cousinni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71410

A child of your aunt or uncle or their descendents. [Definition Source: NCI]
belongs to
concept
KinshipType c

COVID-19 Infectionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C171133

An acute infection of the respiratory tract that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on currently available information, SARS-CoV-2 is thought to mainly spread from person to person through respiratory droplets. Typically, there is a two- to 14-day incubation period and infected persons can present with no symptoms or mild to severe fever, dry cough, fatigue, and difficulty breathing. Dysgeusia, anosmia, and gastrointestinal and flu-like symptoms have also been reported. Older adults and persons of any age who have serious underlying medical conditions may be of higher risk for severe illness, including secondary infections, respiratory failure, and multi-organ dysfunction. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Covid-19 Vaccinesni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/J07BX03

belongs to
concept
Pharmacologic Substance c

Craft and related trades workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C7

Craft and related trades workers apply specific technical and practical knowledge and skills to construct and maintain buildings; form metal; erect metal structures; set machine tools or make, fit, maintain and repair machinery, equipment or tools; carry out printing work; and produce or process foodstuffs, textiles, wooden, metal and other articles, including handicraft goods. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of all stages of the production process, the materials and tools used, and the nature and purpose of the final product. Tasks performed by craft and related trades workers usually include: constructing, maintaining and repairing buildings and other structures; casting, welding and shaping metal; installing and erecting heavy metal structures, tackle and related equipment; making machinery, tools, equipment and other metal articles; setting for operators, or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, engines, vehicles, electrical and electronic instruments and other equipment; making precision instruments, jewellery, household and other precious metal articles, pottery, glass and related products; producing handicrafts; executing printing work; producing and processing foodstuffs and various articles made of wood, textiles, leather and related materials. Supervision of other workers may be included. Self-employed craft and related trades workers, who operate their own businesses either independently or with assistance from a small number of others, may also perform a range of tasks associated with management of the business, account and record keeping and client service, although such tasks would not normally comprise the major component of the work. Occupations in this major group are classified into the following sub-major groups: 71 Building and Related Trades Workers (excluding electricians) 72 Metal, Machinery and Related Trades Workers 73 Handicraft and Printing Workers 74 Electrical and Electronics Trades Workers 75 Food Processing, Woodworking, Garment and Other Craft and Related Trades Workers
belongs to
concept
Occupation c

Cranial Nerve VII Palsyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26769

Partial or complete paralysis of the facial muscles of one side of a person's face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Customer services clerksni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C42

Customer services clerks deal with clients in connection with money-handling operations, travel arrangements, requests for information, making appointments, operating telephone switchboards, and interviewing for surveys or to complete applications for eligibility for services. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: performing money-handling operations in banks, post offices, betting and gambling establishments, or dealing with travel arrangements; supplying information requested by clients and making appointments; operating telephone switchboards; greeting and receiving visitors; interviewing survey respondents; interviewing applicants for services. Occupations in this sub-major group are classified into the following minor groups: 421 Tellers, Money Collectors and Related Clerks 422 Client Information Workers
belongs to
concept
Occupation c

Cutaneous Melanomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3510

A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Cyanocobalaminni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B03BA01

belongs to
concept
Pharmacologic Substance c

Cyclophosphamideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01AA01

belongs to
concept
Pharmacologic Substance c

Cystni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2978

A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Daclizumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AC01

belongs to
concept
Pharmacologic Substance c

Dantroleneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M03CA01

belongs to
concept
Pharmacologic Substance c

Daughterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25165

A female human offspring. [Definition Source: NCI]
belongs to
concept
KinshipType c

DCTN1 Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C122875

This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles. [Definition Source: NCI]
belongs to
concept
Gene c

Deep Vein Thrombosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C49343

A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Deflazacortni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB13

belongs to
concept
Pharmacologic Substance c

Dementiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4786

Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Denosumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M05BX04

belongs to
concept
Pharmacologic Substance c

Depressionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2982

A melancholy feeling of sadness and despair. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Dermatologicalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D

belongs to
concept
Pharmacologic Substance c

Desogestrel and Ethinylestradiolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G03AA09

belongs to
concept
Pharmacologic Substance c

Dexamethasoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB02

belongs to
concept
Pharmacologic Substance c

Diabetes Mellitusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2985

A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Diabetic Ketoacidosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50530

The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Diagnostic Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V04

belongs to
concept
Pharmacologic Substance c

Diagnostic Radiopharmaceuticalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V09

belongs to
concept
Pharmacologic Substance c

Diazepamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA01

belongs to
concept
Pharmacologic Substance c

Dietary Supplementni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C1505

Oral preparations containing dietary ingredient(s) intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites. [Definition Source: NCI]
belongs to
concept
Pharmacologic Substance c

Digestives, incl. Enzymesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A09

belongs to
concept
Pharmacologic Substance c

Dimethyl Fumarateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AX07

belongs to
concept
Pharmacologic Substance c

Diphtheria Vaccinesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J07AF

belongs to
concept
Pharmacologic Substance c

Disease or Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2991

Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Disease, Disorder or Finding Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/diseaseDisorderFindingTaxonomy

This taxonomy comprises disease, disorder or findings. The taxonomy is mainly based on NCIT.
belongs to
concept scheme

Diureticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C03

belongs to
concept
Pharmacologic Substance c

Dog Biteni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C122419

A wound received from the teeth of a dog. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Domperidoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A03FA03

belongs to
concept
Pharmacologic Substance c

Drainage of Bartholin's Abscessni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/236825001

Drainage of abscess of Barholin's gland.
belongs to
concept
Surgical Procedure Type c

Drivers and mobile plant operatorsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C83

Drivers and mobile plant operators drive and tend trains and motor vehicles, or drive, operate and monitor industrial and agricultural machinery and equipment, or execute deck duties on board ship and other water-borne craft. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: driving and tending trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; carrying out deck duties on board ship and other water-borne craft. Occupations in this sub-major group are classified into the following minor groups: 831 Locomotive Engine Drivers and Related Workers 832 Car, Van and Motorcycle Drivers 833 Heavy Truck and Bus Drivers 834 Mobile Plant Operators 835 Ships’ Deck Crews and Related Workers
belongs to
concept
Occupation c

Drospirenone and Ethinylestradiolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G03AA12

belongs to
concept
Pharmacologic Substance c

Drug Hypersensitivity AEni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000890

A hypersensitivity AE that has an outcome of allergic reactions to certain drugs. [Definition Source: OAE]
belongs to
concept
Adverse Drug Reaction c

Drug Hypersensitivity Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112208

A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Drug Intolerance AEni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/OAE_0000891

A drug AE that has an outcome of lower threshold to the normal pharmacologic action of a drug. [Definition Source: OAE]
belongs to
concept
Adverse Drug Reaction c

Drugs for Acid Related Disordersni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A02

belongs to
concept
Pharmacologic Substance c

Drugs for Bile Therapy and Lipotropics in Combinationni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A05C

belongs to
concept
Pharmacologic Substance c

Drugs for Constipationni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A06

belongs to
concept
Pharmacologic Substance c

Drugs for Functional Gastrointestinal Disordersni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A03

belongs to
concept
Pharmacologic Substance c

Drugs for MS Symptomatic Therapyni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DrugsForMSSymptomaticTherapy

Symptomatic therapy for Multiple Sclerosis (MS).
belongs to
concept
Therapeutic Procedure Type c

Drugs for MS Therapy Side Effectsni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DrugsForMSTherapySideEffects

Therapy for managing side effects of MS therapy.
belongs to
concept
Therapeutic Procedure Type c

Drugs for Obstructive Airway Diseasesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R03

belongs to
concept
Pharmacologic Substance c

Drugs for Other Diseasesni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/DrugsForOtherDiseases

Any drugs used to treat other diseases.
belongs to
concept
Therapeutic Procedure Type c

Drugs for Treatment of Bone Diseasesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M05

belongs to
concept
Pharmacologic Substance c

Drugs Used in Diabetesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10

belongs to
concept
Pharmacologic Substance c

Dyslipidemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C80385

A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ectoparasiticides, incl. Scabicides, Insecticides and Repellentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/P03

belongs to
concept
Pharmacologic Substance c

Ecunervni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ecunerv

Ecunerv is recommended to help maintain normal functions of the nervous system under abnormal conditions such as neuropathy (due to mechanical, metabolic, toxic, ischemic, optical, alcoholic, diabetic or post-herpetic causes), canalicular syndrome, radiculopathy. B-vitamins (B1, B6 and B12) work in synergy with magnesium and help maintain normal functions of the nervous system. Vitamin E helps protect cells from oxidative stress. [Definition Source: https://www.ecupharma.it/en/ecunerv - visited on November 28th, 2022]
belongs to
concept
Pharmacologic Substance c

Eczemani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3001

A form of dermatitis characterized by red, itchy, scaly, or crusty patches that can be chronic or intermittent. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Electrical and electronic trades workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C74

Electrical and electronics trades workers install, fit and maintain electrical wiring systems and machinery and other electrical apparatus, electrical transmission and supply lines and cables, and electronic and telecommunications equipment and systems. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: installing, maintaining, fitting and adjusting electrical and electronic wiring systems, machinery and equipment; examining blueprints, wiring diagrams and specifications to determine sequences and methods of operation; inspecting and testing electrical and electronic systems, equipment, cables and machinery to identify hazards, defects and the need for adjustment or repair; installing, maintaining and repairing electrical and telecommunications transmission lines; joining electrical, telecommunications and data cables; maintaining, troubleshooting, fitting, adjusting, testing and repairing electronic equipment such as commercial and office machines, electronic instruments and control systems, computers, and telecommunications and data transmission equipment. Occupations in this sub-major group are classified into the following minor groups: 741 Electrical Equipment Installers and Repairers 742 Electronics and Telecommunications Installers and Repairers
belongs to
concept
Occupation c

Elementary occupationsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C9

Elementary occupations involve the performance of simple and routine tasks which may require the use of hand-held tools and considerable physical effort. Most occupations in this major group require skills at the first ISCO skill level. Tasks performed by workers in elementary occupations usually include: cleaning, restocking supplies and performing basic maintenance in apartments, houses, kitchens, hotels, offices and other buildings; washing cars and windows; helping in kitchens and performing simple tasks in food preparation; delivering messages or goods; carrying luggage and handling baggage and freight; stocking vending-machines or reading and emptying meters; collecting and sorting refuse; sweeping streets and similar places; performing various simple farming, fishing, hunting or trapping tasks; performing simple tasks connected with mining, construction and manufacturing including product-sorting; packing and unpacking produce by hand, and filling shelves; providing various street services; pedalling or hand-guiding vehicles to transport passengers and goods; driving animal-drawn vehicles or machinery. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 91 Cleaners and Helpers 92 Agricultural, Forestry and Fishery Labourers 93 Labourers in Mining, Construction, Manufacturing and Transport 94 Food Preparation Assistants 95 Street and Related Sales and Services Workers 96 Refuse Workers and Other Elementary Workers
belongs to
concept
Occupation c

Emergency Tracheostomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/55622001

Surgical formation of an opening into the trachea through the neck, or the opening so created. [Definition Source: MSH]
belongs to
concept
Surgical Procedure Type c

Emollients and Protectivesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D02

belongs to
concept
Pharmacologic Substance c

Enalaprilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09AA02

belongs to
concept
Pharmacologic Substance c

Endocrine Therapyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L02

belongs to
concept
Pharmacologic Substance c

Endometriosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3014

The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Epidermal Inclusion Cystni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3134

The most common type of cutaneous cyst. It results from the proliferation of epidermal cells in a circumscribed space within the dermis. It is usually asymptomatic and presents as a firm, round nodule. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Escitalopramni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AB10

belongs to
concept
Pharmacologic Substance c

Esomeprazoleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A02BC05

belongs to
concept
Pharmacologic Substance c

Essential Hypertensionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3478

Hypertension that presents without an identifiable cause. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ethnic Groupni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/372148003

A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships. [Definition Source: CSP]
belongs to
concept
Group (social concept) c

Etizolamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA19

belongs to
concept
Pharmacologic Substance c

Etoricoxibni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M01AH05

belongs to
concept
Pharmacologic Substance c

Excision of Basal Cell Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/300025007

Surgical removal of basal cell carcinoma.
belongs to
concept
Surgical Procedure Type c

Excision of Benign Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/118445002

Surgical removal of bening neoplasm.
belongs to
concept
Surgical Procedure Type c

Excision of Cystni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/428297005

Surgical removal of a cyst.
belongs to
concept
Surgical Procedure Type c

Excision of dermatofibromani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/700074001

Surgical removal of dermatofibroma.
belongs to
concept
Surgical Procedure Type c

Excision of Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/370612006

The surgical removal of a neoplasm.
belongs to
concept
Surgical Procedure Type c

Extrapyramidal Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C79593

A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia. Causes include vascular disorders, degenerative disorders, and antipsychotic drugs. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Eyeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12401

The organ of sight or vision. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Fampridineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07XX07

belongs to
concept
Pharmacologic Substance c

Fatherni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25174

A male parent. [Definition Source: NCI]
belongs to
concept
KinshipType c

Favismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34607

A condition associated with glucose-6-phosphate dehydrogenase deficiency, which is characterized by hemolysis. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Femur Fractureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26774

A traumatic or pathologic injury to the femur in which the continuity of the femur is broken. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Fever Chillsni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26921

Shivering secondary to a febrile process. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Fibromani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3041

A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Fibromyalgiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C87497

A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Findingni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3367

Clinical, laboratory or molecular evidence, or absence of evidence of disease. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Fingolimodni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA27

belongs to
concept
Pharmacologic Substance c

First Cousinni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71411

A child of your aunt or uncle. [Definition Source: NCI]
belongs to
concept
KinshipType c

First Degree Relativeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C21481

Any relative who is one meiosis away from a particular individual in a family; a relative with whom one half of an individual's genes is shared (i.e., parent, sibling, offspring) (from Genetics Home Reference glossary) [Definition Source: NCI]
belongs to
concept
KinshipType c

Flu-Like Symptomsni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C78302

Complaints describing a pattern similar to influenza, which may include one or more of the following symptoms: fever, chills, muscle or body aches, cough, sore throat, rhinitis, or fatigue. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Flunarizineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07CA03

belongs to
concept
Pharmacologic Substance c

Fluoxetineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AB03

belongs to
concept
Pharmacologic Substance c

Flurazepamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05CD01

belongs to
concept
Pharmacologic Substance c

Food preparation assistantsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C94

Food preparation assistants prepare and cook to order a small variety of pre-cooked food or beverages, clear tables, clean kitchen areas and wash dishes. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing simple or pre-prepared foods and beverages such as sandwiches, pizzas, fish and chips, salads and coffee; washing, cutting, measuring and mixing foods for cooking; operating cooking equipment such as grills, microwaves and deep-fat fryers; cleaning kitchens, food preparation areas and service areas; cleaning cooking and general utensils used in kitchens and restaurants. Occupations in this sub-major group are classified into the following minor group: 941 Food Preparation Assistants
belongs to
concept
Occupation c

Food processing, wood working, garment and other craft and related trades workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C75

Food processing, woodworking, garment and other craft and related trades workers treat and process agricultural and fisheries raw materials into food and other products, and produce and repair goods made of wood, textiles, fur, leather or other materials. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: treating and processing meat, fish, grain, fruit, vegetables and related materials into food stuffs, and tobacco into tobacco products; tasting and grading food products and beverages; treating and processing natural fibres, skins and hides; making and repairing furniture and other goods made of wood; preparing hides, skins and pelts for further use; making and repairing textiles, garments, hats, shoes and related products. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 751 Food Processing and Related Trades Workers 752 Wood Treaters, Cabinet-makers and Related Trades Workers 753 Garment and Related Trades Workers 754 Other Craft and Related Workers
belongs to
concept
Occupation c

Frontotemporal Dementiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84719

A syndrome caused by progressive degeneration of the frontal or temporal lobes of the brain. It is manifested with personality changes and deterioration of the language skills. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Fungal Infectionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3245

An infection caused by a fungus. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Furosemideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C03CA01

belongs to
concept
Pharmacologic Substance c

FUS Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C91852

This gene is involved in gene expression, genomic integrity and RNA processing. [Definition Source: NCI]
belongs to
concept
Gene c

Gabapentinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AX12

belongs to
concept
Pharmacologic Substance c

Gastritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26780

Inflammation of the stomach. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Gastroenterititsni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34632

An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Gastroesophageal Refluxni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C92560

The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Gastroplastyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/9429009

Surgical procedures involving the STOMACH and sometimes the lower ESOPHAGUS to correct anatomical defects, or to treat MORBID OBESITY by reducing the size of the stomach. There are several subtypes of bariatric gastroplasty, such as vertical banded gastroplasty, silicone ring vertical gastroplasty, and horizontal banded gastroplasty. [Definition Source: MSH]
belongs to
concept
Surgical Procedure Type c

Gastryc Bypassni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/442338001

Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption. [Definition Source: MSH]
belongs to
concept
Surgical Procedure Type c

Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C16612

A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCIT] The taxonomy is based on NCIT.
belongs to
concept scheme

General and keyboard clerksni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C41

General and keyboard clerks record, organize, store and retrieve information and perform a wide range of clerical and administrative tasks according to established procedures. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording, preparing, sorting, classifying and filing information; sorting, opening and sending mail; preparing reports and correspondence of a routine nature; photocopying and faxing documents; operating personal computers, word processors or typewriters to record, input and process text and data; proofreading and correcting copy; preparing invoices and checking figures. Occupations in this sub-major group are classified into the following minor groups: 411 General Office Clerks 412 Secretaries (general) 413 Keyboard Operators
belongs to
concept
Occupation c

General Nutrientsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V06

belongs to
concept
Pharmacologic Substance c

Generalized Epilepsyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3021

A chronic condition characterised by recurrent generalised seizures. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Genito Urinary System and Sex Hormonesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G

belongs to
concept
Pharmacologic Substance c

Gianmaria Silvelloni back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0003-4970-4554

belongs to
Person c

Giorgio Maria Di Nunzioni back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0001-9709-6392

belongs to
Person c

Glatiramer Acetateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AX13

belongs to
concept
Pharmacologic Substance c

Glaucomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26782

Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Gliclazideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10BB09

belongs to
concept
Pharmacologic Substance c

Glimepirideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10BB12

belongs to
concept
Pharmacologic Substance c

Glucocorticoids, Systemicni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB

belongs to
concept
Pharmacologic Substance c

Granddaughterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71399

A female grandchild. [Definition Source: NCI]
belongs to
concept
KinshipType c

Grandfatherni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96573

A male relative who is the biological father of either the biological mother or the biological father. [Definition Source: NCI]
belongs to
concept
KinshipType c

Grandmotherni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96574

A female relative who is the biological mother of either the biological mother or the biological father. [Definition Source: NCI]
belongs to
concept
KinshipType c

Grandsonni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71398

A male grandchild. [Definition Source: NCI]
belongs to
concept
KinshipType c

Group Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/groupTaxonomy

This taxonomy describes the different ethinic groups. The taxonomy is based on SNOMED-CT.
belongs to
concept scheme

Guglielmo Faggiolini back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0002-5070-2049

belongs to
Person c

Gynecological Antiinfectives and Antisepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G01

belongs to
concept
Pharmacologic Substance c

Handicraft and printing workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C73

Handicraft and printing workers combine artistic and manual skills to design, produce, maintain and decorate precision instruments, musical instruments, jewellery and other precious metals, pottery, porcelain and glassware, items made of wood or textile, leather or related materials, and printed products such as books, newspapers and magazines. They apply traditional and/or recently developed techniques to carve, mould, assemble, weave and decorate various articles; to compose and set type prior to printing; to set up and operate printing presses; to bind and finish printed products; and to prepare stencils and operate screen printing equipment. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work may be carried out by hand or involve the use of hand tools and hand-held power tools, and in some cases the set-up and operation of machinery and machine tools. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: making and repairing nautical, meteorological, optical and other precision instruments and equipment; making and repairing musical instruments; making jewellery and precious metalware; making pottery, porcelain ware, ceramics and glassware; painting and decorating various articles; producing handicraft articles in wood or textile, leather and related materials; performing printing or book-binding tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 731 Handicraft Workers 732 Printing Trades Workers
belongs to
concept
Occupation c

Hashimoto Thyroiditisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27191

An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Headni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12419

The anterior and superior part of a human bearing the mouth, the brain and sensory organs. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Head and Neck Approachesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/311801003

Any approach involiving the head and neck region.
belongs to
concept
Surgical Procedure Type c

Head and Neck Findingni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C36282

Symptoms, physical examination results, and/or laboratory test results related to the head and neck. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Head and Neck Surgeryni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15454

Any surgery involving a structure in the head and neck region. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Head Traumani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34660

A traumatic injury to the head. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Headacheni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34661

Pain in various parts of the head, not confined to the area of distribution of any nerve. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Health associate professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C32

Health associate professionals perform technical and practical tasks to support diagnosis and treatment of illness, disease, injuries and impairments in humans and animals, and to support implementation of health care, treatment and referral plans usually established by medical, veterinary, nursing and other health professionals. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in the sub-major group usually include: testing and operating medical imaging equipment and administering radiation therapy; performing clinical tests on specimens of bodily fluids and tissues; preparing medications and other pharmaceutical compounds under the guidance of pharmacists; designing, fitting, servicing and repairing medical and dental devices and appliances; providing nursing and personal care and midwifery support services; using herbal and other therapies based on theories, beliefs and experiences originating in specific cultures. Occupations in this sub-major group are classified into the following minor groups: 321 Medical and Pharmaceutical Technicians 322 Nursing and Midwifery Associate Professionals 323 Traditional and Complementary Medicine Associate Professionals 324 Veterinary Technicians and Assistants 325 Other Health Associate Professionals
belongs to
concept
Occupation c

Health professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C22

Health professionals conduct research,; improve or develop concepts, theories and operational methods; and apply scientific knowledge relating to medicine, nursing, dentistry, veterinary medicine, pharmacy, and promotion of health. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research and obtaining scientific knowledge through the study of human and animal disorders and illnesses and ways of treating them; advising on or applying preventive and curative measures, or promoting health; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 221 Medical Doctors 222 Nursing and Midwifery Professionals 223 Traditional and Complementary Medicine Professionals 224 Paramedical Practitioners 225 Veterinarians 226 Other Health Professionals
belongs to
concept
Occupation c

Heart Failureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50577

Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hepatic Toxicityni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C185645

Toxicity that impairs or damages the liver. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hepatitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3095

Inflammation of the liver; usually from a viral infection, but sometimes from toxic agents. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hepatitis A Infectionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3096

Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hepatitis B, Purified Antigenni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J07BC01

belongs to
concept
Pharmacologic Substance c

Hereditary Factor XI Deficiencyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84705

A rare inherited bleeding disorder caused by deficiency of coagulation factor XI. It may be asymptomatic or manifest with bleeding. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hereditary Hemolytic Anemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34379

A congenital hemolytic anemia caused by defects of the erythrocyte membrane, enzyme deficiencies, or hemoglobinopathies. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Herniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34685

The protrusion of part of an organ or fibroadipose tissue through an abnormal opening. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Herpes Simplex Keratitisni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/9389005

A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) [Defintion Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Herpes Simplex Virus Infectionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C155871

An infection that is caused by herpes simplex virus. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Herpes Zosterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71079

A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

High Grade Cervical Squamous Intraepithelial Neoplasiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C40197

A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hispanicni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/414408004

A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term, "Spanish origin" can be used in addition to "Hispanic or Latino". (OMB) [Definition Source: NCI]
belongs to
concept
Group (social concept) c

Hospital General Universitario Gregorio Marañónni back to ToC or Named Individual ToC

IRI: https://www.comunidad.madrid/hospital/gregoriomaranon/

belongs to
Clinics and Hospitals c

Hospitality, retail and other services managersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C14

Hospitality, retail and other services managers plan, organize and direct the operations of establishments which provide accommodation, hospitality, retail and other services. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning and organizing special functions, sporting, gaming and entertainment activities and the range and mix of products, stock levels and service standards; promoting and selling goods and services; observing liquor, gaming, health and other laws and regulations; developing and reviewing policies, programmes and procedures concerning customer relations and goods and services provided; promoting facilities for conferences, conventions and trade shows to potential customers; organizing the purchase and maintenance of transport vehicles, equipment and fuel, and transporting goods; controlling the selection, training and supervision of staff; ensuring compliance with occupational health and safety regulations. Occupations in this sub-major group are classified into the following minor groups: 141 Hotel and Restaurant Managers 142 Retail and Wholesale Trade Managers 143 Other Services Managers
belongs to
concept
Occupation c

Hydrocortisoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D07AA02

belongs to
concept
Pharmacologic Substance c

Hydrocortisoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB09

belongs to
concept
Pharmacologic Substance c

Hydroxychloroquineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/P01BA02

belongs to
concept
Pharmacologic Substance c

Hypercholesterolemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C37967

A laboratory test result indicating an increased amount of cholesterol in the blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hypersensitivityni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3114

An immune response that occurs following exposure to an innocuous antigen, but that does not require the presence of preformed antibodies to the antigen. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hypertensionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3117

Blood pressure that is abnormally high. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hypertensive Crisisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3122

A severe, acute increase in blood pressure that may result in stroke or myocardial ischemia. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hyperthyroidismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3123

Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Hypnotics and Sedativesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05C

belongs to
concept
Pharmacologic Substance c

Hypothyroidismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26800

Abnormally low levels of thyroid hormone. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Hysterectomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/236886002

A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). [Definition source: NCI]
belongs to
concept
Surgical Procedure Type c

Ibuprofenni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M01AE01

belongs to
concept
Pharmacologic Substance c

Ichthyosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84776

A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Immune Sera and Immunoglobulinsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J06

belongs to
concept
Pharmacologic Substance c

Immunoactive Drugsni back to ToC or Named Individual ToC

IRI: https://w3id.org/brainteaser/ontology/schema/ImmunoactiveDrugs

Therapy employed to slow the progression of the disease.
belongs to
concept
Therapeutic Procedure Type c

Immunoglobulins, Normal Human, for Intravascular Adm.ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J06BA02

belongs to
concept
Pharmacologic Substance c

Immunostimulantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03

belongs to
concept
Pharmacologic Substance c

Immunosuppressantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04

belongs to
concept
Pharmacologic Substance c

Indometacinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M01AB01

belongs to
concept
Pharmacologic Substance c

Infectious Mononucleosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34726

A clinical syndrome of fever, sore throat, fatigue, and lymphadenopathy caused by infection with the Epstein-Barr virus. Subsequent physical findings may include hepatomegaly, palatal petechiae, jaundice, uvular edema, and splenomegaly. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Information and communications techniciansni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C35

Information and communications technicians provide support for the day-to-day running of computer systems, communications systems and networks, and perform technical tasks related to telecommunications, broadcast image and sound as well as other types of telecommunications signals on land, sea or in aircraft. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing assistance to information and communications systems users; installing new programs and equipment; establishing, operating and maintaining network and other data communications systems; installing, monitoring and supporting Internet and Intranet websites or web server hardware or software; modifying web pages; and performing web server backup and recovery operations; controlling equipment to record sound, edit and mix image and sound recordings; controlling and maintaining transmitting and broadcast systems and satellite systems for radio and television programmes; controlling and maintaining radio communications systems, satellite services and multiplex systems on land, sea or in aircraft; providing technical assistance connected with research and development of computer systems and telecommunications equipment, or testing prototypes; designing and preparing blueprints of circuitry according to the specifications given; providing technical supervision of the manufacture, utilization, maintenance and repair of telecommunications systems. Occupations in this sub-major group are classified into the following minor groups: 351 Information and Communications Technology Operations and User Support Technicians 352 Telecommunications and Broadcasting Technicians
belongs to
concept
Occupation c

Information and communications technology professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C25

Information and communications technology professionals conduct research; plan, design, write, test, provide advice and improve information technology systems, hardware, software and related concepts for specific applications; develop associated documentation including principles, policies and procedures; and design, develop, control, maintain and support databases and other information systems to ensure optimal performance and data integrity and security. Tasks performed by workers in this sub-major group usually include: researching information technology use in business functions; identifying areas for improvement and researching the theoretical aspects and operational methods for the use of computers; evaluating, planning and designing hardware or software configurations for specific applications including for Internet, Intranet and multimedia systems; designing, writing, testing and maintaining computer programs; designing and developing database architecture and database management systems; developing and implementing security plans and data administration policy, and administering computer networks and related computing environments; analysing, developing, interpreting and evaluating complex system design and architecture specifications, data models and diagrams in the development, configuration and integration of computer systems. Occupations in this sub-major group are classified into the following minor groups: 251 Software and Applications Developers and Analysts 252 Database and Network Professionals
belongs to
concept
Occupation c

Inguinal Herniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34690

The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Injuryni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3671

Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Insertion of Implantable Intrathecal Access Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/445968009

Surgical insertion of intrathecal access system for drug delivery.
belongs to
concept
Surgical Procedure Type c

Institute of Molecular Medicine Joao Lobo Antunesni back to ToC or Named Individual ToC

IRI: https://imm.medicina.ulisboa.pt/

belongs to
Clinics and Hospitals c

Insulin Glargineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10AE04

belongs to
concept
Pharmacologic Substance c

Insulin Lisproni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10AB04

belongs to
concept
Pharmacologic Substance c

Insulins and Analoguesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10A

belongs to
concept
Pharmacologic Substance c

Interferon Beta Naturalni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AB02

belongs to
concept
Pharmacologic Substance c

Interferon Beta-1ani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AB07

belongs to
concept
Pharmacologic Substance c

Interferon Beta-1bni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AB08

belongs to
concept
Pharmacologic Substance c

Interstitial Pneumoniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27006

Inflammation of interstitial lung tissue, usually associated with infection. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Intervertebral Disc Prolapseni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/73589001

Herniated Disc [Definition Source: MedDRA]
belongs to
concept
Disease, Disorder or Finding c

Intestinal Pseudo-Obstructionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34733

Ileus of the intestine in which there is no mechanical obstruction. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Iridocyclitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34736

Inflammation of the iris and the ciliary body. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Iron-Deficiency Anemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84484

Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Keratitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26805

Inflammation of the cornea. [Definition Source: NCI]
belongs to
Disease, Disorder or Finding c

Keratoconusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26806

A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ketorolacni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M01AB15

belongs to
concept
Pharmacologic Substance c

Kinship Type Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/kinshipTypeTaxonomy

This taxonomy describes the different type of relative a person can have. The taxonomy is based on NCIT.
belongs to
concept scheme

Klippel-Feil Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C98967

A rare congenital syndrome characterized by the fusion of the vertebrae in the cervical spine. Patients present with a short neck and restricted mobility of the upper spine. Other signs and symptoms include scoliosis, spina bifida, cleft palate, and rib malformations. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Labourers in mining, construction, manufacturing and transportni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C93

Labourers in mining, construction, manufacturing and transport perform simple and routine manual tasks in mining, quarrying, civil engineering, building, manufacturing, transport and storage operations, and operate human-powered and animal-drawn vehicles and machinery. Most occupations in this sub-major group require skills at the first ISCO skill level. Task performed by workers in this sub-major group usually include: digging holes and spreading excavated materials, sand, soil and gravel using hand-held tools; sorting, loading, unloading, moving, stacking and storing materials, equipment, products, supplies, baggage and cargo by hand; cleaning machinery, equipment, tools and work sites; packing and unpacking material and products and filling containers and shelves with products by hand; operating human-powered and animal-drawn vehicles and machinery. Occupations in this sub-major group are classified into the following minor groups: 931 Mining and Construction Labourers 932 Manufacturing Labourers 933 Transport and Storage Labourers
belongs to
concept
Occupation c

Lactuloseni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A06AD11

belongs to
concept
Pharmacologic Substance c

Lamotrigineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AX09

belongs to
concept
Pharmacologic Substance c

Langerhans Cell Histiocytosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3107

A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001) [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Laura Menottini back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0002-0676-682X

belongs to
Person c

Legal, social and cultural professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C26

Legal, social and cultural professionals conduct research; improve or develop concepts, theories and operational methods; or apply knowledge relating to the law, storage and retrieval of information and artefacts, psychology, social welfare, politics, economics, history, religion, languages, sociology, other social sciences, and arts and entertainment. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research on legal problems; drafting laws and regulations; advising clients on legal cases; pleading and conducting cases in a court of law; presiding over judicial proceedings in a court of law; developing and maintaining library and gallery collections of archives; conducting research, improving or developing concepts, theories and operational methods or applying knowledge relating to the field of social sciences; conceiving, creating and performing in literary and artistic works; interpreting and communicating news, ideas, impressions and facts. Occupations in this sub-major group are classified into the following minor groups: 261 Legal Professionals 262 Librarians, Archivists and Curators 263 Social and Religious Professionals 264 Authors, Journalists and Linguists 265 Creative and Performing Artists
belongs to
concept
Occupation c

Legal, social, cultural and related associate professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C34

Legal, social, cultural and related associate professionals perform technical tasks connected with the practical application of knowledge relating to legal services, social work, culture, food preparation, sport and religion. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing technical and practical services and support functions in legal processes and investigations, social and community assistance programmes, and religious and cultural activities; participating and adjudicating in sporting events; developing and delivering sports coaching, fitness and recreational programmes; combining creative and technical skills in a variety of artistic, cultural and culinary activities; creating dishes and menus and overseeing the preparation of meals. Occupations in this sub-major group are classified into the following minor groups: 341 Legal, Social and Religious Associate Professionals 342 Sports and Fitness Workers 343 Artistic, Cultural and Culinary Associate Professionals
belongs to
concept
Occupation c

Lercanidipineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C08CA13

belongs to
concept
Pharmacologic Substance c

Leukopeniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26816

A laboratory test result indicating a decreased number of white blood cells in the peripheral blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Levetiracetamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AX14

belongs to
concept
Pharmacologic Substance c

Levodopa and Decarboxylase Inhibitorni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04BA02

belongs to
concept
Pharmacologic Substance c

Levothyroxine Sodiumni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H03AA01

belongs to
concept
Pharmacologic Substance c

Limbni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12429

A body region referring to an upper or lower extremity. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Lipid Modifying Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C10

belongs to
concept
Pharmacologic Substance c

Liver Therapy, Lipotropicsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A05B

belongs to
concept
Pharmacologic Substance c

Long QT Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34786

A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Losartanni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09CA01

belongs to
concept
Pharmacologic Substance c

Lower Extremityni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12742

The limb that is composed of the hip, thigh, leg and foot. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Lumbar Herniani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/23344004

Lumbar Hernia [Definition Source: SNOMEDCT]
belongs to
concept
Disease, Disorder or Finding c

Lumbar Puncture Headacheni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50643

Headache in erect position, after lumbar puncture; due to lowering of intracranial pressure by leakage of cerebrospinal fluid through the needle tract. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Lumbar Spineni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C69314

Those vertebrae between the ribs and the pelvis, L1-L5 in man. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Lumbosacral Regionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C48824

The part of the spine in the lower back that consists of the lumbar region and the sacrum. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Lymphopeniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26823

An abnormally small number of lymphocytes in the circulating blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Malgradateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A02AD02

belongs to
concept
Pharmacologic Substance c

Malignant Colon Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C9242

A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Malignant Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C9305

A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Malignant Skin Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2920

A primary or metastatic malignant neoplasm involving the skin. Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Malignant Thyroid Gland Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C7510

A primary or metastatic malignant neoplasm affecting the thyroid gland. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Managersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C1

Managers plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations, or of organizational units within them, and formulate and review their policies, laws, rules and regulations. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level, except for Sub-major Group 14: Hospitality, Retail and Other Services Managers, for which skills at the third ISCO skill level are generally required. Tasks performed by managers usually include: formulating and advising on the policy, budgets, laws and regulations of enterprises, governments and other organizational units; establishing objectives and standards and formulating and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise and of its staff; selecting or approving the selection of staff; ensuring compliance with health and safety requirements; planning and directing daily operations; representing and negotiating on behalf of the government, enterprise or organizational unit managed in meetings and other forums. Occupations in this major group are classified into the following sub-major groups: 11 Chief Executives, Senior Officials and Legislators 12 Administrative and Commercial Managers 13 Production and Specialized Services Managers 14 Hospitality, Retail and Other Services Managers
belongs to
concept
Occupation c

Market-oriented skilled agricultural workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C61

Market-oriented skilled agricultural workers plan, organize and perform farming operations to grow and harvest field or tree and shrub crops; and to produce a variety of animals and animal products for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; raising, breeding and tending animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; storing and carrying out some processing of produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 611 Market Gardeners and Crop growers 612 Animal Producers 613 Mixed Crop and Animal Producers
belongs to
concept
Occupation c

Market-oriented skilled forestry, fishery and hunting workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C62

Market-oriented skilled forestry, fishery and hunting workers plan, organize and perform operations to cultivate, conserve and exploit natural and plantation forests; breed and raise fish; harvest and catch fish; and hunt and trap animals, for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: renting or investing in equipment and machinery and purchasing supplies; planning and undertaking forestry, aquaculture, fishery and hunting operations; maintaining buildings, tanks, machinery and other equipment; delivering or marketing products; supervising and training other workers. Occupations in this sub-major group are classified into the following minor groups: 621 Forestry and Related Workers 622 Fishery Workers, Hunters and Trappers
belongs to
concept
Occupation c

Maternal Auntni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96575

A female relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

Maternal Uncleni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96579

A male relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

Medicated Dressingsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D09

belongs to
concept
Pharmacologic Substance c

Melanocytic Nevusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C7570

A neoplasm composed of melanocytes that usually appears as a dark spot on the skin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Melatoninni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05CH01

belongs to
concept
Pharmacologic Substance c

Mesalazineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A07EC02

belongs to
concept
Pharmacologic Substance c

Metal, machinery and related trades workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C72

Metal, machinery and related trades workers cast, weld, forge and, by other methods, form metal; erect, maintain and repair heavy metal structures; engage in machine-tool setting as well as in fitting, maintaining and repairing machinery including engines and vehicles; or they produce tools and various non-precious metal articles. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product Tasks performed by workers in this sub-major group usually include: making moulds and cores for casting metal; casting, welding and shaping metal; installing, erecting, maintaining and repairing heavy metal structures, tackle and related equipment; forging and forming steel and other non-precious metals to make and repair machinery, tools, equipment and other articles; setting for operators or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, including engines and vehicles. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 721 Sheet and Structural Metal Workers, Moulders and Welders, and Related Workers 722 Blacksmiths, Toolmakers and Related Trades Workers 723 Machinery Mechanics and Repairers
belongs to
concept
Occupation c

Metforminni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10BA02

belongs to
concept
Pharmacologic Substance c

Methotrexateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01BA01

belongs to
concept
Pharmacologic Substance c

Methotrexateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AX03

belongs to
concept
Pharmacologic Substance c

Methylprednisoloneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB04

belongs to
concept
Pharmacologic Substance c

Migraineni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C89715

A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Migraine With Aurani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C117005

A migraine disorder characterized by episodes that are preceded by focal neurological symptoms. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Mineral Supplementsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A12

belongs to
concept
Pharmacologic Substance c

Mitoxantroneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01DB07

belongs to
concept
Pharmacologic Substance c

Mitrazapineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AX11

belongs to
concept
Pharmacologic Substance c

Modafinilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06BA07

belongs to
concept
Pharmacologic Substance c

Molluscum Contagiosum Virusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112357

A species of enveloped and brick-shaped viruses in the Poxviridae family and Molluscipoxvirus genus. The genome is composed of non-segmented, linear double-stranded DNA. Molluscum contagiosum viruses are found in humans and can cause the disease Molluscum contagiosum. Molluscum contagiosum viruses are transmitted via direct person-to-person contact and contact with infected fomites. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Mondino Foundationni back to ToC or Named Individual ToC

IRI: https://www.mondino.it/

belongs to
Clinics and Hospitals c

Monoclonal B_Cell Lymphocytosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C80310

A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia. It precedes virtually all cases of chronic lymphocytic leukemia/small lymphocytic lymphoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Monoclonal Gammopathyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35548

An abnormal laboratory test result indicating the presence of monoclonal immunoglobulins in the blood or urine. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Mood Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C92200

A category of psychiatric disorders which have as their most predominant feature a disturbance in mood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Motherni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25189

A female parent. [Definition Source: NCI]
belongs to
concept
KinshipType c

Motor Neuron Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/37340000

Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) [Definition Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Multiple Sclerosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3243

A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Mumpsni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C29888

A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Muscle Relaxantsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M03

belongs to
concept
Pharmacologic Substance c

Musculo-Skeletal Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M

belongs to
concept
Pharmacologic Substance c

Myasthenia Gravisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C60989

A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Myeloproliferative Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4345

A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008) [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Naltrexoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07BB04

belongs to
concept
Pharmacologic Substance c

Nasal Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R01

belongs to
concept
Pharmacologic Substance c

Natalizumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA23

belongs to
concept
Pharmacologic Substance c

Nebivololni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07AB12

belongs to
concept
Pharmacologic Substance c

Neckni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C13063

The region that connects the head to the rest of the body. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Neck Traumani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/90460009

General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck. [Defintion Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Neonatal Hearing Impairmentni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50667

An abnormality that affects hearing within the first month after birth. It may or may not result in hearing loss. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3262

A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Nephewni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71409

A son of your brother or sister. [Definition Source: NCI]
belongs to
concept
KinshipType c

Nervous Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N

belongs to
concept
Pharmacologic Substance c

Neurofibromatosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C6727

An autosomal dominant hereditary neoplastic syndrome. Two distinct clinicopathological entities are recognized: neurofibromatosis type 1 and neurofibromatosis type 2. Neurofibromatosis type 1 is associated with the presence of cafe-au-lait cutaneous lesions, multiple neurofibromas, malignant peripheral nerve sheath tumors, optic nerve gliomas, and bone lesions. Neurofibromatosis type 2 is associated with the presence of schwannomas, meningiomas, and gliomas. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Neutropenic Disorderni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/303011007

A decrease in the number of NEUTROPHILS found in the blood. [Definition Source: MSH]
belongs to
concept
Disease, Disorder or Finding c

Nicergolineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C04AE02

belongs to
concept
Pharmacologic Substance c

Nicola Ferroni back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0001-9219-6239

belongs to
Person c

Nieceni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C71408

A daughter of your brother or sister. [Definition Source: NCI]
belongs to
concept
KinshipType c

Non-commissioned armed forces officersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C02

Non-commissioned armed forces officers enforce military discipline and supervise the activities of those employed in Sub-major Group 03: Armed Forces Occupations, Other Ranks, and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes members of the armed forces holding ranks such as sergeant, warrant officer and sergeant major. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 021 Non-commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.
belongs to
concept
Occupation c

Non-Invasive Mechanical Ventilation (NIV)ni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C171457

A type of mechanical ventilation procedure that uses a non-invasive means, such as a face mask or nasal mask, to deliver oxygenated air into the lungs. [Definition Source: NCI]
belongs to
concept
Therapeutic Procedure Type c

Non-Neoplastic Central Nervous System Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27586

Any disorder other than abnormal tissue growth resulting from uncontrolled cell proliferation affecting the nervous system.
belongs to
concept
Disease, Disorder or Finding c

Numerical and material recording clerksni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C43

Numerical and material recording clerks obtain, compile and compute accounting, bookkeeping, statistical, financial and other numerical data, and take charge of cash transactions incidental to business matters. Some occupations classified here keep records of goods produced, purchased, stocked and dispatched, and of materials needed at specified production dates, or keep records of operational aspects and coordinate the timing of passenger and freight transport. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: helping with accounting and bookkeeping records and computations; calculating unit production costs; calculating wages and in some cases preparing wage packets and paying wages; taking charge of cash transactions incidental to the business; obtaining, compiling and computing statistical or actuarial data; performing clerical tasks relating to the financial transactions of an insurance establishment, bank or similar establishment; recording produced, stocked, ordered and dispatched goods; recording production materials received, put into stock or issued; computing quantities of the production materials required at specified dates and helping with preparation and checking of production operation schedules; keeping records of operational aspects and coordinating the timing of passenger and freight transport. Occupations in this sub-major group are classified into the following minor groups: 431 Numerical Clerks 432 Material Recording and Transport Clerks
belongs to
concept
Occupation c

Obesityni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3283

Having a high amount of body fat (body mass index [BMI] of 30 or more). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Obstructive Sleep Apnea Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C27168

A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Occupation Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/occupationTaxonomy

This taxonomy describes the occupation of a person. The taxonomy is based on ECO occupations.
belongs to
concept scheme

Ocrelizumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA36

belongs to
concept
Pharmacologic Substance c

Olanzapineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05AH03

belongs to
concept
Pharmacologic Substance c

Olmesartan Medoxomilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09CA08

belongs to
concept
Pharmacologic Substance c

Operation on Abdominal Regionni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/21371007

A surgical procedure located in the abdomnial region.
belongs to
concept
Surgical Procedure Type c

Operative Procedure on Lumbosacral Spinal Structureni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/428402007

Lumbo-sacral spine surgery
belongs to
concept
Surgical Procedure Type c

Operative Procedure on Thoracic Spinal Structureni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/428614005

Thoracic spine surgery.
belongs to
concept
Surgical Procedure Type c

Operative Procedure on Upper Extremityni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/107769006

Surgical procedure involving an upper extremity.
belongs to
concept
Surgical Procedure Type c

Ophthalmologicalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/S01

belongs to
concept
Pharmacologic Substance c

Ophthalmologicals and Otologicals Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/S03

belongs to
concept
Pharmacologic Substance c

Opioid Use Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C157942

The use of opioids that results in the development of a dependency that adversely affects an individual's life. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Optic Neuritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C84950

A disorder characterized by inflammation of the optic nerve. Causes include autoimmune disorders, infections, toxins, drugs, and multiple sclerosis. It may manifest with acute loss of vision and pain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

OPTN Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C119640

This gene plays a role in both neuroprotection and Golgi maintenance [Definition Source: NCI]
belongs to
concept
Gene c

Osteoporosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3298

A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Other Alimentary Tract and Metabolismni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A16

belongs to
concept
Pharmacologic Substance c

Other clerical support workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C44

Other clerical support workers sort and deliver mail, file documents, prepare information for processing, maintain personnel records, check material for consistency with original source material, assist persons who cannot read or write, and perform various other specialized clerical duties. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording information regarding acquisition, issue and return of library books; classifying and filing various documents and other records; maintaining personnel records; sorting, recording and delivering mail from post offices, as well as from or within an enterprise; coding; correcting proofs; performing a range of miscellaneous clerical duties; writing on behalf of persons who are unable to read or write. Occupations in this sub-major group are classified into the following minor group: 441 Other Clerical Support Workers
belongs to
concept
Occupation c

Other Dermatological Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D11

belongs to
concept
Pharmacologic Substance c

Other Drugs for Disorders of the Musculo-Skeletal Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M09

belongs to
concept
Pharmacologic Substance c

Other Gynecologicalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G02

belongs to
concept
Pharmacologic Substance c

Other Hematological Agentsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B06

belongs to
concept
Pharmacologic Substance c

Other Nervous System Drugsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07

belongs to
concept
Pharmacologic Substance c

Other Respiratory System Productsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R07

belongs to
concept
Pharmacologic Substance c

Other Vaccinesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J07BX

belongs to
concept
Pharmacologic Substance c

Otologicalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/S02

belongs to
concept
Pharmacologic Substance c

Oxcarbazepineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AF02

belongs to
concept
Pharmacologic Substance c

Oxybutyninni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04BD04

belongs to
concept
Pharmacologic Substance c

Paliperidoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05AX13

belongs to
concept
Pharmacologic Substance c

Palmar Fibromatosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3469

A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males. [Definition Source: NCI] It has exact synonim: Dupuytren Contracture; Palmar Fibromatosis; Dupuytren's Contracture.
belongs to
concept
Disease, Disorder or Finding c

Pancreatic Hormonesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H04

belongs to
concept
Pharmacologic Substance c

Pancytopeniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34889

A finding of low numbers of red and white blood cells and platelets in the peripheral blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pantoprazoleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A02BC02

belongs to
concept
Pharmacologic Substance c

Paracetamolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02BE01

belongs to
concept
Pharmacologic Substance c

Parkinson's Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26845

A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Paroxetineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AB05

belongs to
concept
Pharmacologic Substance c

Partial Cystectomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/112902005

The surgical removal of part of bladder.
belongs to
concept
Surgical Procedure Type c

Paternal Auntni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96581

A female relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

Paternal Uncleni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96585

A male relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

Peginterferon Alfa-2bni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AB10

belongs to
concept
Pharmacologic Substance c

Peginterferon Beta-1ani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L03AB13

belongs to
concept
Pharmacologic Substance c

Pelvisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12767

The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Penicillin Allergyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34911

An allergy to Penicillin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Percutaneous Endoscopic Gastrostomy (PEG)ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/235159007

The placement of a feeding tube through the abdominal wall into the stomach using an endoscope. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Perindopril and Amlodipineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09BB04

belongs to
concept
Pharmacologic Substance c

Peripheral Vasodilatorsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C04

belongs to
concept
Pharmacologic Substance c

Personal care workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C53

Personal care workers provide care, supervision and assistance for children, patients and elderly, convalescent or disabled persons in institutional and residential settings. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assisting with mobility, washing and other personal needs; assisting children individually to learn social skills; supervising and participating in activities that enhance children’s physical, social, emotional and intellectual development; observing and reporting concerns to appropriate health or social service workers. Occupations in this sub-major group are classified into the following minor groups: 531 Child Care Workers and Teachers’ Aides 532 Personal Care Workers in Health Services
belongs to
concept
Occupation c

Personal service workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C51

Personal services workers provide personal services related to travel, housekeeping, catering and hospitality, hairdressing and beauty treatment, animal care grooming and training, companionship and other services of a personal nature. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: organizing and providing services in connection with travel and sightseeing; housekeeping; preparing and serving food and beverages; hairdressing and beauty treatment; telling fortunes; embalming and arranging funerals; grooming, caring for and training animals; teaching people to drive motor vehicles; providing companionship and other personal services. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 511 Travel Attendants, Conductors and Guides 512 Cooks 513 Waiters and Bartenders 514 Hairdressers, Beauticians and Related Workers 515 Building and Housekeeping Supervisors 516 Other Personal Services Workers
belongs to
concept
Occupation c

Personality Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34922

A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pharmacologic Substanceni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C1909

Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCIT] The taxonomy is based on ATC.
belongs to
concept scheme

Phenobarbitalni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AA02

belongs to
concept
Pharmacologic Substance c

Phenytoinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AB02

belongs to
concept
Pharmacologic Substance c

Pituitary and Hypothalamic Hormones and Analoguesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H01

belongs to
concept
Pharmacologic Substance c

Pituitary Neuroendocrine Tumorni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3329

A well-differentiated neuroendocrine neoplasm that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. It has a low frequency of metastatic spread. When metastatic, the term metastatic pituitary neuroendocrine tumor is endorsed instead of pituitary carcinoma. (WHO) [Definition Source: NCI] It has exact synonim: Pituitary Gland Adenoma.
belongs to
concept
Disease, Disorder or Finding c

Plant and machine operators and assemblersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C8

Plant and machine operators and assemblers operate and monitor industrial and agricultural machinery and equipment on the spot or by remote control; drive and operate trains, motor vehicles and mobile machinery and equipment; or assemble products from component parts according to strict specifications and procedures. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of industrial and agricultural machinery and equipment, as well as an ability to cope with machine-paced operations and to adapt to technological innovations. Tasks performed by plant and machine operators and assemblers usually include: operating and monitoring mining or other industrial machinery and equipment for processing metal, minerals, glass, ceramics, wood, paper or chemicals; operating and monitoring machinery and equipment used to produce articles made of metal, minerals, chemicals, rubber, plastics, wood, paper, textiles, fur or leather, and which process foodstuffs and related products; driving and operating trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; and assembling products from component parts according to strict specifications and procedures. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 81 Stationary Plant and Machine Operators 82 Assemblers 83 Drivers and Mobile Plant Operators
belongs to
concept
Occupation c

Plasmapheresisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C15304

A procedure that collects plasma from the peripheral blood while returning the rest to the donor. [Definition Source: NCI]
belongs to
concept
Therapeutic Procedure Type c

Pleural Effusionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3331

Increased amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough, and chest pain. It is usually caused by lung infections, congestive heart failure, pleural and lung tumors, connective tissue disorders, and trauma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pneumococcal Pneumoniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C157959

Pneumonia that is attributed to the bacteria Streptococcus pneumonia. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pneumoniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3333

An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pneumonia Caused By SARS-CoV-2ni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/882784691000119100

Pneumonia caused by severe acute respiratory syndrome coronavirus 2 [Definition Source: SNOMEDCT]
belongs to
concept
Disease, Disorder or Finding c

Poliomyelitis, Trivalent, Inactivated, Whole Virusni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J07BF03

belongs to
concept
Pharmacologic Substance c

Post-Herpetic Neuralgiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C117084

Pain that occurs after the disappearance of herpes zoster infection lesions. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pramipexoleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04BC05

belongs to
concept
Pharmacologic Substance c

Prasugrelni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01AC22

belongs to
concept
Pharmacologic Substance c

Prazepamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05BA11

belongs to
concept
Pharmacologic Substance c

Prednisoloneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB06

belongs to
concept
Pharmacologic Substance c

Prednisoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H02AB07

belongs to
concept
Pharmacologic Substance c

Pregabalinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AX16

belongs to
concept
Pharmacologic Substance c

Preparations for Treatment of Wounds and Ulcersni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/D03

belongs to
concept
Pharmacologic Substance c

Primary Neoplasmni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C8509

A tumor at the original site of origin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Primary Progressive Aphasiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C85024

A rare neurologic progressive disorder characterized by impairment of the language and speech abilities. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Procedure on Pelvic Region of Trunkni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/609637006

Pelvic surgery.
belongs to
concept
Surgical Procedure Type c

Production and specialised services managersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C13

Production and specialized services managers plan, direct and coordinate the production of the goods and the provision of the specialized professional and technical services provided by an enterprise or organization, either as the manager of a department or as the general manager of an enterprise or organization that does not have a hierarchy of managers. They are responsible for manufacturing, mining, construction, logistics, information and communications technology operations for large-scale agricultural, forestry and fisheries operations, and for the provision of health, education, social welfare, banking, insurance and other professional and technical services. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning details of activities in terms of output, services provided, quality, quantity, cost, timeliness and labour requirements; setting standards and objectives; controlling the operation of plant and of procedures; assuring quality of the goods produced and services provided; preparing tenders and contract bids; establishing and managing budgets, monitoring costs, and adjusting activities, procedures and resources to minimize costs; overseeing the acquisition and installation of new plant and equipment; coordinating the implementation of health and safety requirements; planning and directing daily operations; overseeing the selection, training and performance of staff; preparing, or arranging for the preparation of, reports, budgets and forecasts; representing the enterprise or organization in negotiations with other agencies, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 131 Production Managers in Agriculture, Forestry and Fisheries 132 Manufacturing, Mining, Construction and Distribution Managers 133 Information and Communications Technology Services Managers 134 Professional Services Managers
belongs to
concept
Occupation c

Professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C2

Professionals increase the existing stock of knowledge; apply scientific or artistic concepts and theories; teach about the foregoing in a systematic manner; or engage in any combination of these activities. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level. Tasks performed by professionals usually include: conducting analysis and research, and developing concepts, theories and operational methods; advising on or applying existing knowledge related to physical sciences, mathematics, engineering and technology, life sciences, medical and health services, social sciences and humanities; teaching the theory and practice of one or more disciplines at different educational levels; teaching and educating persons with learning difficulties or special needs; providing various business, legal and social services; creating and performing works of art; providing spiritual guidance; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 21 Science and Engineering Professionals 22 Health Professionals 23 Teaching Professionals 24 Business and Administration Professionals 25 Information and Communications Technology Professionals 26 Legal, Social and Cultural Professionals
belongs to
concept
Occupation c

Progestogens and Estrogens Systemic Contraceptives, Sequential Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G03AB

belongs to
concept
Pharmacologic Substance c

Proglumideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A02BX06

belongs to
concept
Pharmacologic Substance c

Progressive Multifocal Leukoencephalopathyni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26815

A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Prolapsed Lumbar Intervertebral Discni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/202708005

Lumbar Hernia [Definition Source: MedDRA]
belongs to
concept
Disease, Disorder or Finding c

Propanololni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C07AA05

belongs to
concept
Pharmacologic Substance c

Protective services workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C54

Protective services workers protect individuals and property against fire and other hazards, maintain law and order and enforce laws and regulations. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preventing, fighting and extinguishing fires; rescuing people from burning buildings and accident sites and those trapped in dangerous situations; maintaining law and order, enforcing laws and regulations, patrolling public areas and arresting suspected offenders; directing traffic and assuming authority in the event of accidents; watching over and maintaining order among inmates of prisons, reformatories or penitentiaries; patrolling or monitoring premises to guard property against theft and vandalism, controlling access to establishments and maintaining order and enforcing regulations at public events and within establishments. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 541 Protective Services Workers
belongs to
concept
Occupation c

Proteinuriani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C38012

The presence of abnormal amounts of protein in the urine. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Psoriasisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3346

An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Psoriatic Arthritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C61277

Joint inflammation associated with psoriasis. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Psychiatric Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2893

A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Psychoanalepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06

belongs to
concept
Pharmacologic Substance c

Psycholepticsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05

belongs to
concept
Pharmacologic Substance c

Pulmonary Embolismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50713

The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pulmonary Sarcoidosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34997

Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Pulmonary Thromboembolismni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/233935004

Pulmonary embolism is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. [PMID:29770793]
belongs to
concept
Disease, Disorder or Finding c

Quetiapineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05AH04

belongs to
concept
Pharmacologic Substance c

Radius Fractureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C99039

Traumatic or pathological injury to the radius bone in which the continuity of the bone is broken. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ramiprilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09AA05

belongs to
concept
Pharmacologic Substance c

Reboxetineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AX18

belongs to
concept
Pharmacologic Substance c

Refuse workers and other elementary workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C96

Refuse workers and other elementary workers collect, process and recycle garbage from buildings, yards, streets and other public places. They keep streets and other public places clean and tidy, deliver and carry messages and packages and perform odd jobs for private households or establishments. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, loading and unloading garbage; sweeping streets, parks and other public places; chopping firewood; collecting and carrying firewood, water, packages, luggage and messages; beating dust out of carpets and performing other odd-job tasks. Occupations in this sub-major group are classified into the following minor groups: 961 Refuse Workers 962 Other Elementary Workers
belongs to
concept
Occupation c

Relativeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C21480

A person related by blood or marriage. [Definition Source: NCIT]
belongs to
concept
KinshipType c

Removal of Acoustic Neuromani back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/300009002

Surgical removal of acoustic neuroma.
belongs to
concept
Surgical Procedure Type c

Renal Colicni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C78593

Paroxysmal and severe flank pain radiating to the inguinal area. It is caused by the passage of a kidney stone through the ureter. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Repair of Bladderni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/74146001

Surgical repair of bladder
belongs to
concept
Surgical Procedure Type c

Respiratory Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R

belongs to
concept
Pharmacologic Substance c

Retinal Detachmentni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26874

An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Rheumatoid Arthritisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2884

A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Rifampicinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J04AB02

belongs to
concept
Pharmacologic Substance c

Riluzoleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N07XX02

belongs to
concept
Pharmacologic Substance c

Rituximabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01XC02

belongs to
concept
Pharmacologic Substance c

Rivaroxabanni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01AF01

belongs to
concept
Pharmacologic Substance c

Rivastigmineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06DA03

belongs to
concept
Pharmacologic Substance c

Ropiniroleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N04BC04

belongs to
concept
Pharmacologic Substance c

Sales workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C52

Sales workers sell and demonstrate goods in wholesale or retail shops, at stalls and markets, door-to-door, via telephone or customer contact centres. They may record and accept payment for goods and services purchased, and may operate small retail outlets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: selling goods in wholesale or retail establishments, at street or market stalls, door-to-door, via telephone or customer contact centres; demonstrating and displaying goods to potential customers; selling and serving food for immediate consumption at counters and in the street; buying or contracting a regular supply of products to be sold; stacking and displaying goods for sale and wrapping or packing goods sold; determining product mix, stock and price levels for goods to be sold; operating cash registers, optical price scanners, computers or other equipment to record and accept payment for the purchase of goods and services. Supervision of other workers may be required in some occupations classified here. Occupations in this sub-major group are classified into the following minor groups: 521 Street and Market Salespersons 522 Shop Salespersons 523 Cashiers and Ticket Clerks 524 Other Sales Workers
belongs to
concept
Occupation c

Sarcoidosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C34995

An idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, and skin. Cardiac involvement is also possible. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Scarlet Feverni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C94575

A streptococcal infection, mainly occurring among children, that is characterized by a red skin rash, sore throat, and fever. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Science and engineering associate professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C31

Science and engineering associate professionals perform technical tasks connected with research and operational methods in science and engineering. They supervise and control technical and operational aspects of mining, manufacturing, construction and other engineering operations, and operate technical equipment including aircraft and ships. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: setting up, monitoring and operating instruments and equipment, conducting and monitoring experiments and tests of systems; collecting and testing samples; recording observations and analysing data; preparing, revising and interpreting technical drawings and diagrams; coordinating, supervising, controlling and scheduling the activities of other workers; operating and monitoring switchboards, computerized control systems, and multi-function process control machinery; performing technical functions to ensure safe and efficient movement and operations in ships, aircraft and other equipment. Occupations in this sub-major group are classified into the following minor groups: 311 Physical and Engineering Science Technicians 312 Mining, Manufacturing and Construction Supervisors 313 Process Control Technicians 314 Life Science Technicians and Related Associate Professionals 315 Ship and Aircraft Controllers and Technicians
belongs to
concept
Occupation c

Science and engineering professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C21

Science and engineering professionals conduct research; improve or develop concepts, theories and operational methods; or apply scientific knowledge relating to fields such as physics, astronomy, meteorology, chemistry, geophysics, geology, biology, ecology, pharmacology, medicine, mathematics, statistics, architecture, engineering, design and technology. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research, enlarging, advising on or applying scientific knowledge obtained through the study of structures and properties of physical matter and phenomena, chemical characteristics and processes of various substances, materials and products, all forms of human, animal and plant life and of mathematical and statistical concepts and methods; advising on, designing and directing construction of buildings, towns and traffic systems, or civil engineering and industrial structures, as well as machines and other equipment; advising on and applying mining methods and ensuring their optimum use; surveying land and sea and making maps; studying and advising on technological aspects of particular materials, products and processes, and on efficiency of production and work organization; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 211 Physical and Earth Science Professionals 212 Mathematicians, Actuaries and Statisticians 213 Life Science Professionals 214 Engineering Professionals (excluding Electrotechnology) 215 Electrotechnology Engineers 216 Architects, Planners, Surveyors and Designers
belongs to
concept
Occupation c

Second Degree Relativeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C19811

Any relative who is two meioses away from a particular individual in a family; a relative with whom one quarter of an individual's genes is shared (i.e., grandparent, grandchild, uncle, aunt, nephew, niece, half-sibling) (from Genetics Home Reference glossary) [Definition Source: NCI]
belongs to
concept
KinshipType c

Secukinumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AC10

belongs to
concept
Pharmacologic Substance c

Seizure Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3020

A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Sensory Organsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/S

belongs to
concept
Pharmacologic Substance c

Serositisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C70428

Inflammation of a serous membrane. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Sertralineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AB06

belongs to
concept
Pharmacologic Substance c

Serum Glutamic Pyruvic Transaminase, CTCAEni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C55098

An enzyme that is normally present in liver and heart cells. SGPT is released into blood when the liver or heart is damaged. The blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Also called alanine aminotransferase (ALT). [Definition Source: RxList] Common Terminology Criteria for Adverse Events (CTCAE) [Definition Source: U.s. Department of Health and Human Services]
belongs to
concept
Disease, Disorder or Finding c

Service and sales workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C5

Services and sales workers provide personal and protective services related to travel, housekeeping, catering, personal care, protection against fire and unlawful acts; or demonstrate and sell goods in wholesale or retail shops and similar establishments, as well as at stalls and on markets. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by services and sales workers usually include: organizing and providing services during travel; housekeeping; preparing and serving of food and beverages; caring for children; providing personal and basic health care at homes or in institutions, as well as hairdressing, beauty treatment and companionship; telling fortunes; embalming and arranging funerals; providing security services and protecting individuals and property against fire and unlawful acts; enforcing of law and order; posing as models for advertising, artistic creation and display of goods; selling goods in wholesale or retail establishments, as well as at stalls and on markets; and demonstrating goods to potential customers. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 51 Personal Services Workers 52 Sales Workers 53 Personal Care Workers 54 Protective Services Workers
belongs to
concept
Occupation c

Sex Hormones and Modulators of the Genital Systemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G03

belongs to
concept
Pharmacologic Substance c

Shoulder Dislocationni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35020

A dislocation of the shoulder joint. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Signni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C53458

Objective evidence of disease perceptible to the examining healthcare provider. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Sign or Symptomni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C100104

Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Sildenafilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04BE03

belongs to
concept
Pharmacologic Substance c

Simvastatinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C10AA01

belongs to
concept
Pharmacologic Substance c

Sinusitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35024

An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Siponimodni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA42

belongs to
concept
Pharmacologic Substance c

Sisterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C111202

A female who shares with her sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]
belongs to
concept
KinshipType c

Sitagliptinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A10BH01

belongs to
concept
Pharmacologic Substance c

Sjogren Syndromeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26883

An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Skilled agricultural, forestry and fishery workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C6

Skilled agricultural, forestry and fishery workers grow and harvest field or tree and shrub crops; gather wild fruits and plants; breed, tend or hunt animals; produce a variety of animal husbandry products; cultivate, conserve and exploit forests; breed or catch fish; and cultivate or gather other forms of aquatic life in order to provide food, shelter and income for themselves and their households. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by skilled agricultural, forestry and fishery workers usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; gathering wild fruits and plants; breeding, raising, tending or hunting animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; cultivating, conserving and exploiting forests; breeding or catching fish; cultivating or gathering other forms of aquatic life; storing and carrying out some basic processing of their produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 61 Market-oriented Skilled Agricultural Workers 62 Market-oriented Skilled Forestry, Fishery and Hunting Workers 63 Subsistence Farmers, Fishers, Hunters and Gatherers
belongs to
concept
Occupation c

Skin Basal Cell Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2921

The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Skin Basosquamous Cell Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2922

A basal cell carcinoma which displays squamous differentiation. The neoplastic cells have more abundant cytoplasm with more marked keratinization than typical basal cell carcinomas. It usually has a more aggressive clinical course compared to typical basal cell carcinoma, and it may produce regional or widespread metastases. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Skin Carcinomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4914

A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Skin Cystni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3884

A cystic lesion located in the skin. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

SOD1 Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C54578

This gene plays a role in the detoxification of superoxide radicals in the cytosol. [Definition Source: NCI]
belongs to
concept
Gene c

Sonni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C25205

A male human offspring. [Definition Source: NCI]
belongs to
concept
KinshipType c

Sphincterni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28381

A circular band of muscle that functions to regulate the size of an orifice in the body. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Spina Bifidani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C101214

A congenital neural tube defect in which vertebrae are not fully formed. It results in the protrusion of the spinal cord through the opening of the vertebrae. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Spinal and Bulbar Muscular Atrophy, X-linked 1ni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C85233

A rare, slowly progressive degenerative disorder affecting males. It is caused by mutations in the androgen receptor (AR) gene. It is characterized by bulbar and limb muscle weakness and atrophy, and gynecomastia. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Spinal Cordni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12464

The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. [Definition Source: NCI][attribution: On-line Medical Dictionary]
belongs to
concept
Anatomic Site c

SQSTM1 Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C101491

This gene is involved in signal transduction. [Definition Source: NCI]
belongs to
concept
Gene c

Staphylococcal Infectionni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35038

Infection by Staphylococcus. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Stationary plant and machine operatorsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C81

Stationary plant and machine operators monitor and operate stationary industrial plant, machinery and equipment, or for which mobility is not an integral part of operation. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of the industrial plant, machinery or equipment being operated and monitored. Ability to cope with machine-paced operations and to adapt to innovations in machinery and equipment are often required. Tasks performed by workers in this sub-major group usually include: setting up, operating and monitoring a variety of stationary plant and machinery; detecting malfunctions and taking corrective action; examining outputs for defects and conformity with specifications and adjusting machine settings accordingly; performing maintenance, repairs and cleaning; recording data and maintaining production records. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 811 Mining and Mineral Processing Plant Operators 812 Metal Processing and Finishing Plant Operators 813 Chemical and Photographic Products Plant and Machine Operators 814 Rubber, Plastic and Paper Products Machine Operators 815 Textile, Fur and Leather Products Machine Operators 816 Food and Related Products Machine Operators 817 Wood Processing and Papermaking Plant Operators 818 Other Stationary Plant and Machine Operators
belongs to
concept
Occupation c

Stefano Marchesinni back to ToC or Named Individual ToC

IRI: https://orcid.org/0000-0003-0362-5893

belongs to
Person c

Stomatological Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A01

belongs to
concept
Pharmacologic Substance c

Street and related sales and service workersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C95

Street and related sales and services workers sell goods (excluding food) for immediate consumption, and provide a variety of services on streets and in other public places such as stations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: buying or making various items for sale; loading and unloading items for sale and transporting them; obtaining the materials necessary to perform services; approaching people on the street to offer goods or services; cleaning and polishing shoes; cleaning and polishing car windows; running errands; assisting car drivers to find a parking place and ensuring that the car is not damaged during the driver’s absence; handing out leaflets and free newspapers; receiving immediate payment. Occupations in this sub-major group are classified into the following minor groups: 951 Street and Related Services Workers 952 Street Vendors (excluding Food)
belongs to
concept
Occupation c

Strokeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3390

A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Subdural Hematomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C116585

A collection of blood between the dura mater and the brain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Subsistence farmers, fishers, hunters and gatherersni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C63

Subsistence farmers, fishers, hunters and gatherers grow and harvest field or tree and shrub crops, vegetables and fruit; gather wild fruits, medicinal and other plants; tend or hunt animals; catch fish and gather various forms of aquatic life in order to provide food, shelter and, in some cases, a minimum of cash income for themselves and their households. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, tending and harvesting field crops; growing vegetables, fruit and other tree and shrub crops; gathering wild fruits, medicinal and other plants; breeding, tending and feeding animals and poultry mainly to obtain meat, eggs, milk, hair, skin or other products; hunting or trapping animals; catching fish and gathering other forms of aquatic life; fetching water and gathering firewood; storing produce for later use and carrying out some processing of produce; building and maintaining houses and other shelters; making tools, clothes and utensils for use by the household; selling or bartering some products at local markets. Occupations in this sub-major group are classified into the following minor groups: 631 Subsistence Crop Farmers 632 Subsistence Livestock Farmers 633 Subsistence Mixed Crop and Livestock Farmers 634 Subsistence Fishers, Hunters, Trappers and Gatherers
belongs to
concept
Occupation c

Sulfasalazineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A07EC01

belongs to
concept
Pharmacologic Substance c

Supratentorial Brainni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12512

The part of the brain that is located superior to the tentorium cerebelli. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Surgical Dressingsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V20

belongs to
concept
Pharmacologic Substance c

Surgical Procedure on Cervical Spineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/428490009

Surgical procedure on the cervical spine.
belongs to
concept
Surgical Procedure Type c

Surgical Procedure on Lower Extremityni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/107784002

Surgical procedure involiving a lower extremity.
belongs to
concept
Surgical Procedure Type c

Surgical Procedure on Thoraxni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/385487005

Any surgery performed inside the thoracic cavity. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Surgical Procedure Type Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/surgicalProcedureTypeTaxonomy

This taxonomy describes the type of surgical procedures. The taxonomy is based on SNOMED-CT.
belongs to
concept scheme

Symptomni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C4876

Subjective evidence of disease perceived by the patient. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Syncopeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35053

A spontaneous loss of consciousness caused by insufficient blood supply to the brain. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Systemic Hormonal Preparations, excl. Sex Hormones and Insulinsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H

belongs to
concept
Pharmacologic Substance c

Tamoxifenni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L02BA01

belongs to
concept
Pharmacologic Substance c

Tamsulosinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04CA02

belongs to
concept
Pharmacologic Substance c

TARDBP Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C80020

This gene is involved in transcription and mRNA splicing. [Definition Source: NCI]
belongs to
concept
Gene c

TBK1 Geneni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C24845

This gene plays a role in the immune response and signal transduction. [Definition Source: NCI]
belongs to
concept
Gene c

Teaching professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C23

Teaching professionals teach the theory and practice of one or more disciplines at different educational levels; conduct research; improve or develop concepts, theories and operational methods pertaining to their particular discipline; and prepare scholarly papers and books. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting classes, courses, or tutorials at a particular educational level for educational and vocational purposes, including private lessons; conducting adult literacy programmes; teaching and educating persons with learning difficulties or special needs; designing and modifying curricula; inspecting and advising on teaching methods and aids; participating in decisions concerning the organization of teaching and related activities at schools and universities; conducting research in particular subjects to improve or develop concepts, theories or operational methods for application in industrial and other fields; preparing scholarly papers and books. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 231 University and Higher Education Teachers 232 Vocational Education Teachers 233 Secondary Education Teachers 234 Primary School and Early Childhood Teachers 235 Other Teaching Professionals
belongs to
concept
Occupation c

Technicians and associate professionalsni back to ToC or Named Individual ToC

IRI: http://data.europa.eu/esco/isco/C3

Technicians and associate professionals perform technical and related tasks connected with research and the application of scientific or artistic concepts and operational methods, and government or business regulations. Competent performance in most occupations in this major group requires skills at the third ISCO skill level. Tasks performed by technicians and associate professionals usually include: undertaking and carrying out technical work connected with research and the application of concepts and operational methods in the fields of physical sciences including engineering and technology, life sciences including the medical profession, and social sciences and humanities; initiating and carrying out various technical services related to trade, finance and administration including administration of government laws and regulations, and to social work; providing technical support for the arts and entertainment; participating in sporting activities; executing some religious tasks. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 31 Science and Engineering Associate Professionals 32 Health Associate Professionals 33 Business and Administration Associate Professionals 34 Legal, Social, Cultural and Related Associate Professionals 35 Information and Communications Technicians
belongs to
concept
Occupation c

Telmisartanni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C09CA07

belongs to
concept
Pharmacologic Substance c

Teriflunomideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AA31

belongs to
concept
Pharmacologic Substance c

Tetanus Immunoglobulinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J06BB02

belongs to
concept
Pharmacologic Substance c

Tetracosactideni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H01AA02

belongs to
concept
Pharmacologic Substance c

Thalassemiani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35069

An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Therapeutic Procedure Type Taxonomyni back to ToC or Named Individual ToC

IRI: https://w3id.org/hereditary/ontology/phenoclinical/schema/therapeuticProcedureType

This taxonomy describes the type of therapeutic procedures. The taxonomy is manly based on NCIT.
belongs to
concept scheme

Therapeutic Radiopharmaceuticalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V10

belongs to
concept
Pharmacologic Substance c

Thiamazoleni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H03BB02

belongs to
concept
Pharmacologic Substance c

Thiethylperazineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R06AD03

belongs to
concept
Pharmacologic Substance c

Third Degree Relativeni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C100808

Any individual related biologically or legally to another individual and considered two degrees removed from the immediate family as in the case of cousins. [Definition Source: NCI]
belongs to
concept
KinshipType c

Thoracic Spinal Cordni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12894

The portion of the spinal cord located in the thoracic region. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Thoracic Spineni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C69315

The vertebrae of the thoracic spine, numbered one through twelve in man. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Thoracic Traumani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C171204

Trauma to the chest. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Thoraxni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12799

The division of the body lying between the neck and the abdomen. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Throat Preparationsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/R02

belongs to
concept
Pharmacologic Substance c

Thrombocytopeniani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3408

A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Thromboembolismni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C28195

Occlusion of the lumen of a vessel by a thrombus that has migrated from a distal site via the blood stream. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Thyroid Gland Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26893

A non-neoplastic or neoplastic disorder that affects the thyroid gland. Representative examples include hyperthyroidism, hypothyroidism, thyroiditis, follicular adenoma, and carcinoma. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Thyroid Gland Excisionni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/13619001

Surgery to remover part or all of the thyroid gland. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Thyroid Therapyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/H03

belongs to
concept
Pharmacologic Substance c

Thyroiditisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26894

Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Tibia Fractureni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C99083

Traumatic or pathological injury to the tibia in which the continuity of the bone is broken. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Ticlopidineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01AC05

belongs to
concept
Pharmacologic Substance c

Tinea Versicolorni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C112833

A skin condition characterized by hypopigmented, pink or tan, confetti-like, discrete and confluent scaly macules distributed on the chest, shoulders and upper back. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Tizanidineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M03BX02

belongs to
concept
Pharmacologic Substance c

Tocilizumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AC07

belongs to
concept
Pharmacologic Substance c

Tolterodineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04BD07

belongs to
concept
Pharmacologic Substance c

Tonicsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A13

belongs to
concept
Pharmacologic Substance c

Tooth Abscessni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35475

An infectious process that affects a tooth. It is characterized by localized periapical or periodontal collection of pus. It presents with pain and swelling of the gums and/or cheek. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Topical Products for Joint and Muscular Painni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/M02

belongs to
concept
Pharmacologic Substance c

Topiramateni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AX11

belongs to
concept
Pharmacologic Substance c

Toxoplasmosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3418

A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Transient Ischemic Attackni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C50781

A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Transurethral Prostatectomyni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/SNOMEDCT/90199006

Prostate tissue removal via a cystoscope. [Definition Source: NCI]
belongs to
concept
Surgical Procedure Type c

Trastuzumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L01XC03

belongs to
concept
Pharmacologic Substance c

Trazodoneni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AX05

belongs to
concept
Pharmacologic Substance c

Triazolamni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05CD05

belongs to
concept
Pharmacologic Substance c

Trigeminal Nerve Disorderni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26952

A non-neoplastic or neoplastic disorder affecting the trigeminal nerve (fifth cranial nerve). [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Trospiumni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04BD09

belongs to
concept
Pharmacologic Substance c

Two Vessel Coronary Diseaseni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C100023

There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in two coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery). (ACC) [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Type 1 Diabtes Mellitusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2986

A chronic condition characterized by minimal or absent production of insulin by the pancreas. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Type 2 Diabetes Mellitusni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26747

A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Uncleni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C96587

A male relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]
belongs to
concept
KinshipType c

University of Paduani back to ToC or Named Individual ToC

IRI: https://www.unipd.it/

belongs to
Clinics and Hospitals c

University of Turinni back to ToC or Named Individual ToC

IRI: https://www.unito.it/

belongs to
Clinics and Hospitals c

Upper Extremityni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12671

The region of the body that includes the arm, the forearm, and hand. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Ureteral Stenosisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C115958

Narrowing of the luminal diameter of one or both ureters due to intrinsic factors. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Urologicalsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/G04

belongs to
concept
Pharmacologic Substance c

Ursodeoxycholic Acidni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A05AA02

belongs to
concept
Pharmacologic Substance c

Ustekinumabni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/L04AC05

belongs to
concept
Pharmacologic Substance c

Uterine Corpus Leiomyomani back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C3434

A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Vaccinesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J07

belongs to
concept
Pharmacologic Substance c

Valaciclovirni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/J05AB11

belongs to
concept
Pharmacologic Substance c

Valproic Acidni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AG01

belongs to
concept
Pharmacologic Substance c

Variousni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/V

belongs to
concept
Pharmacologic Substance c

Vasoprotectivesni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C05

belongs to
concept
Pharmacologic Substance c

Venlafaxineni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N06AX16

belongs to
concept
Pharmacologic Substance c

Verapamilni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/C08DA01

belongs to
concept
Pharmacologic Substance c

Vertebral Columnni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C12998

A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. [Definition Source: NCI]
belongs to
concept
Anatomic Site c

Vertigoni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C38057

A feeling of movement, a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). Vertigo is medically distinct from dizziness, lightheadedness, and unsteadiness. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Vigabatrinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N03AG04

belongs to
concept
Pharmacologic Substance c

Viral Pericarditisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C128405

Pericarditis that is caused by an infection with a viral agent. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Vitaminsni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/A11

belongs to
concept
Pharmacologic Substance c

Vitiligoni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C26915

Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes. [Definition Source: NCI][attribution: NICHD]
belongs to
concept
Disease, Disorder or Finding c

Vulvovaginal Candidiasisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C2914

Infection of the vulva and vagina with a fungus of the genus CANDIDA. It is a disease associated with HIV infection. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Vulvovaginitisni back to ToC or Named Individual ToC

IRI: http://purl.obolibrary.org/obo/NCIT_C35131

An inflammatory pathologic process that affects the vulva and the vagina. [Definition Source: NCI]
belongs to
concept
Disease, Disorder or Finding c

Warfarinni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/B01AA03

belongs to
concept
Pharmacologic Substance c

Zolmitriptanni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N02CC03

belongs to
concept
Pharmacologic Substance c

Zolpidemni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05CF02

belongs to
concept
Pharmacologic Substance c

Zuclopenthixolni back to ToC or Named Individual ToC

IRI: http://purl.bioontology.org/ontology/UATC/N05AF05

belongs to
concept
Pharmacologic Substance c

Legend back to ToC

c: Classes
op: Object Properties
dp: Data Properties
ni: Named Individuals

References back to ToC

Acknowledgments back to ToC

This project has received funding from the HEREDITARY Project, as part of the European Union’s Horizon Europe research and innovation programme under grant agreement No GA 101137074.

The authors would like to thank Silvio Peroni for developing LODE, a Live OWL Documentation Environment, which is used for representing the Cross Referencing Section of this document and Daniel Garijo for developing Widoco, the program used to create the template used in this documentation.