The Hereditary Ontology for Phenoclinical Data
type: Ontology
version IRI: https://w3id.org/hereditary/ontology/phenoclinical/1.0/
imports: Pollution.owl
imports: core
creator: Laura Menotti
creator: Gianmaria Silvello
description: The Hereditary ontology models clinical and genomics data to provide a unifying layer to query different database sources through an Ontology-Based Data Access (OBDA) framework. This part of the ontology focuses on phenoclinical data for ALS and MS patients.
license: Copyright 2024-2027 University of Padua, Italy Licensed under the Creative Commons Attribution 4.0 International License https://creativecommons.org/licenses/by/4.0/ You may obtain a copy of the License at https://creativecommons.org/licenses/by/4.0/legalcode This work has been supported by the HEREDITARY project https://hereditary-project.eu/ funded by the European Union’s Horizon Europe research and innovation programme under the grant agreement No GA101137074
version info: 1.0

alternative label
type: AnnotationProperty
comment: The range of skos:altLabel is the class of RDF plain literals.
comment: skos:prefLabel, skos:altLabel and skos:hiddenLabel are pairwise disjoint properties.
definition: An alternative lexical label for a resource.
example: Acronyms, abbreviations, spelling variants, and irregular plural/singular forms may be included among the alternative labels for a concept. Mis-spelled terms are normally included as hidden labels (see skos:hiddenLabel).
sub property of: label

change note
type: AnnotationProperty
definition: A note about a modification to a concept.
sub property of: note

definition
type: AnnotationProperty
definition: A statement or formal explanation of the meaning of a concept.
sub property of: note

editorial note
type: AnnotationProperty
definition: A note for an editor, translator or maintainer of the vocabulary.
sub property of: note

example
type: AnnotationProperty
definition: An example of the use of a concept.
sub property of: note

hidden label
type: AnnotationProperty
comment: The range of skos:hiddenLabel is the class of RDF plain literals.
comment: skos:prefLabel, skos:altLabel and skos:hiddenLabel are pairwise disjoint properties.
definition: A lexical label for a resource that should be hidden when generating visual displays of the resource, but should still be accessible to free text search operations.
sub property of: label

history note
type: AnnotationProperty
definition: A note about the past state/use/meaning of a concept.
sub property of: note

note
type: AnnotationProperty
definition: A general note, for any purpose.
scope note: This property may be used directly, or as a super-property for more specific note types.

preferred label
type: AnnotationProperty
comment: A resource has no more than one value of skos:prefLabel per language tag, and no more than one value of skos:prefLabel without language tag.
comment: The range of skos:prefLabel is the class of RDF plain literals.
comment: skos:prefLabel, skos:altLabel and skos:hiddenLabel are pairwise disjoint properties.
definition: The preferred lexical label for a resource, in a given language.
sub property of: label

scope note
type: AnnotationProperty
definition: A note that helps to clarify the meaning and/or the use of a concept.
sub property of: note

is produced by
type: ObjectProperty
domain: Air pollution concentration
range: SensingDevice
comment: Relation between a producer and a produced entity: for example, between a sensor and the produced output.

APConcentrationTime
type: ObjectProperty
domain: Air pollution concentration
range: Instant
comment: It defines the relationship between air pollution concentration individuals and their time of recording.

administration
type: ObjectProperty
domain: Therapeutic Treatment
range: Administration
comment: It defines the relationship between a therapeutic treatment and the specific administration details.

adverseReaction
type: ObjectProperty
domain: End Therapy Reason
range: Adverse Drug Reaction
comment: It defines the relationship between The end therapy reason and the adverse reaction occurred.

anatomicalLocation
type: ObjectProperty
domain: Class
  union of: Diagnostic Imaging
  union of: Onset
  union of: Surgical Procedure
  union of: Trauma
range: Anatomic Site
comment: It defines the location of a trauma, onset, surgical procedure or diagnostic imaging.

birthplace
type: ObjectProperty
domain: Person
range: Place
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032040
comment: It defines the relationship between a person and his or her birthplace.

coexistingPregnancy
type: ObjectProperty
domain: Relapse
range: Pregnancy
comment: It defines the relationship between a relapse and a co-occurring pregnancy.

conductedInClinic
type: ObjectProperty
domain: Clinical Trial
range: Clinics and Hospitals
comment: It defines the relationship between a clinical trial and a clinic or hospital. In particular, a clinical trial is conducted in a clinic or hospital.

confirmedPregnancy
type: ObjectProperty
domain: End Therapy Reason
range: Pregnancy
comment: It defines the relationship between the end therapy reason and a pregnancy, meaning the therapeutic treatment was interrupted due to a confirmed pregnancy.

consists
type: ObjectProperty
domain: Event
range: Intervention or Procedure
comment: It defines the relationship between an event and an intervetion or procedure. In particular, an event could consist in an intervention or procedure.

coveredPlace
type: ObjectProperty
domain: SensingDevice
range: Place
comment: It defines the relationship between the sensing device for environmental data and the covered place.

determinedBy
type: ObjectProperty
type: FunctionalProperty
domain: Comorbidity
range: Disease, Disorder or Finding
comment: It defines the relationship between a comorbidity and the disease that determines it.

enrolledIn
type: ObjectProperty
domain: Person
range: Clinical Trial Participation
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997894
comment: It defines the relationship between a person and a clinical trial participation. In particular, a person can be enrolled in a clinical trial participation.

hasDisease
type: ObjectProperty
domain: Person
range: Disease, Disorder or Finding
comment: It defines the relationship between a person and a disease which he or she suffers from.

hasEthnicity
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Group (social concept)
comment: It defines the patient's ethnicity. For instance, we say that: :Peter :hasEthnicity _:b . _:b a Group (social concept); a skos:Concept.

hasKinship
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Kinship
comment: It defines the relation between a patient and a kinship. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.
note: This property is functional because we refer only to biological kinship thus a person can only have one biological kinship with a specific person.

hasKinshipType
type: ObjectProperty
type: FunctionalProperty
domain: Kinship
range: KinshipType
comment: It defines the relation between a Kinship and a KinshipType. For instance, we say that: :Peter :hasKinship _:b . _:b a Kinship; :hasKinshipType http://aunt. http://aunt a KinshipType; a skos:Concept.

hasOccupation
type: ObjectProperty
type: FunctionalProperty
domain: Patient
range: Occupation
comment: It defines the relationship between a patient and his or her occupation.

hasRegisteredActivity
type: ObjectProperty
domain: Event
range: Activity
comment: It defines the relationsihip between an event and an activity. In particular, during an event a specific type of activity can be registered.

hasRegisteredCondition
type: ObjectProperty
domain: Event
range: Conditon
comment: It defines the relationsihip between an event and a comorbidity. In particular, during an event a preexisting condition can be registered.

inClinicalTrial
type: ObjectProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: Clinical Trial
comment: It defines the relationship between a clinical trial participation and a clinical trial. In particular, a clinical trial participation refers to a clinical trial.

inKinshipWith
type: ObjectProperty
domain: Kinship
range: Person
comment: The relationship of kinship between a patient with another Person (who might also be a Patient)

isAboutDisease
type: ObjectProperty
domain: Clinical Trial
range: Disease, Disorder or Finding
comment: It defines the relationship between a clinical trial and the disease studied in it.

observedResult
type: ObjectProperty
domain: Hematology Test
range: Laboratory Test Result
comment: It defines the relationship between an hematology test and the observed laboratory results.

onGene
type: ObjectProperty
domain: Genetic Testing
range: Gene
comment: It defnies the relationship between a genetic testing and a gene. In particular, a genetic testing looks for some genetic mutations on a gene.

performedTreatment
type: ObjectProperty
domain: Therapeutic Procedure
range: Therapeutic Treatment
comment: It defines the relationship between the therapeutic procedure and the perfomed therapeutic treatments.

pharmacologicSubstance
type: ObjectProperty
domain: Therapeutic Treatment
range: Pharmacologic Substance
comment: It defines the relationship between a therapeutic treatment and the employed pharmacologic subastance.

placeLocation
type: ObjectProperty
type: FunctionalProperty
domain: Residence
range: Place
comment: It defines the relationship between a patient's residence and its location.

pregnancy
type: ObjectProperty
domain: Event
range: Pregnancy
comment: It defines the relationship between an event and a pregnancy that can be registrered during the event.

relapse
type: ObjectProperty
domain: Event
range: Relapse
comment: It defines the relationship between an event and a relapse that can be registered during the event.

requiredMRI
type: ObjectProperty
domain: Relapse
range: Magnetic Resonance Imaging (MRI)
comment: It defines the relationship between a relapse and a MRI that has been required.

residence
type: ObjectProperty
domain: Person
range: Residence
comment: It defines the relationship between a person and his or her residence.

surgicalType
type: ObjectProperty
type: FunctionalProperty
domain: Surgical Procedure
range: Surgical Procedure Type
comment: It defines the realtionship between the surgical procedure and the specific type of surgical procedure.

tested
type: ObjectProperty
domain: Patient
range: Genetic Testing
comment: It defines the relationship betwen a patient and a genetic testing. In particular, a patient can be tested for genetic mutations.

testedForOligoclonalBands
type: ObjectProperty
type: FunctionalProperty
domain: CSF Analysis
range: Oligoclonal Bands
comment: It defines the relationship between a CSF Analysis and a test for the presence of oligoclonal bands.

therapyType
type: ObjectProperty
domain: Therapeutic Treatment
range: Therapeutic Procedure Type
comment: It defines the relationship between the therapeutic treatment and the type of therapeutic procedure that has been administered.

trauma
type: ObjectProperty
domain: Event
range: Trauma
comment: It defines the relationship between an event and a trauma that can be registered during the event.

undergo
type: ObjectProperty
domain: Patient
range: Event
comment: It defines the relationship between patient and event. In particular, a patient can undergo some events.

comprisesPlace
type: ObjectProperty
domain: Local Health Autority
range: Place
comment: links the Local Health Autority to the administred territories.

IgGIndexCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The IgG index is the ratio of the quotients for IgG and albumin (IgGcsf/IgGs)/(Albcsf/Albs). It is a quantitative analysis of the relationship between CSF IgG and serum IgG, divided by the same relationship for albumin. [Definition Source: Simonsen, Cecilia Smith et al. “The diagnostic value of IgG index versus oligoclonal bands in cerebrospinal fluid of patients with multiple sclerosis.” Multiple sclerosis journal - experimental, translational and clinical vol. 6,1 2055217319901291. 22 Jan. 2020]

MSInPaediatricAge
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: An indicator of whether the patient contracted Multiple Sclerosis (MS) in paediatric age.

abdominalSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an abdominal surgery.

activityEndYear
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: The year in which an activity ended.

acitivityStartYear
type: DatatypeProperty
type: FunctionalProperty
domain: Activity
range: gYear
comment: The year in which the activity started.

activityType
type: DatatypeProperty
domain: Physical Activity
range: PlainLiteral
comment: The type of physical activity carried out.

administrationFrequency
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2982514
comment: The frequency of administration of the pharmacological substance.

administrationRoute
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013153
comment: Designation of the part of the body through which or into which, or the way in which, the medicinal product is intended to be introduced. In some cases a medicinal product can be intended for more than one route and/or method of administration. [Definition Source: NCI][attribution: ICH]

administrationUoM
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1319591
comment: The Unit of Measure (UoM) of the adminstration dose.

administrationDose
type: DatatypeProperty
type: FunctionalProperty
domain: Administration
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2986169
comment: A definite quantity of a medicine or drug given or prescribed to be given at one time. [Definition Source: Oxford English Dictionary]

ageOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0206132
comment: Age of the patient at the onset.

albuminCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of albumin present in a sample of CSF. Unit of measure : [mg/l].

alcoholUse
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: boolean
comment: Whether a patient drinks alcohol.

alive
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: Whether the patient is still alive.

alsfrs1
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 1 for ALSFRS: Speech.

alsfrs10
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 10 for Revised ALSFRS: Dyspnea.

alsfrs11
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 11 for Revised ALSFRS: Orthopnea.

alsfrs12
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 12 for Revised ALSFRS: Respiratory Insufficiency.

alsfrs2
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 2 for ALSFRS: Salivation.

alsfrs3
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 3 for ALSFRS: Swallowing.

alsfrs4
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 4 for ALSFRS: Handwriting.

alsfrs5
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 5 for ALSFRS: Cutting food and handling utensilis.

alsfrs6
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 6 for ALSFRS: Dressing and hygiene.

alsfrs7
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 7 for ALSFRS: Turning in bed and adjusting blankets.

alsfrs8
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 8 for ALSFRS: Walking.

alsfrs9
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Item 9 for ALSFRS: Climbing Stairs.

alsfrsOriginal10
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Original item 10 for ALSFRS: Breathing.

alterationCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: Datatype
  one of: atypical alteration for MS
  one of: normal
  one of: traumatic
  one of: typical alteration for MS
comment: Whether the CSF specimen is normal or presents alterations.

ambulationEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for ambulation.

autoimmuneDisease
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had an autoimmune disease.

axialOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced axial onset. The Axial Skeleton is the part of the skeleton that includes the skull and spinal column and sternum and ribs. [Definition Source: NCI]

before20Years
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: boolean
comment: Whether a patient smoked before the age of 20.

birthYear
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: gYear
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2826771
comment: The year in which a person was born. [Definition Source: NCI]

bodyMassIndex
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
comment: Weight in kilograms divided by the square of the height in metres, used esp. as an indicator of obesity or general nutritional status; also called Quetelet index; abbreviated BMI. [Definition Source: Oxford English Dictionary]

bowelAndBladderEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for bowel and bladder functions.

bowelAndBladderRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved bowel and bladder functions.

brainAtrophyMRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: Datatype
  one of: high
  one of: mild
  one of: moderate
  one of: none
comment: The level of brain atrophy (cerebral atrophy) found in the brain of the patient shown by the MRI.

brainstemRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the brainstem functions.

brainstemEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for brainstem functions.

bulbarOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced bulbar onset, which means he or she first notice speech or swallowing problems. [Definition Source: National Institute of Neurological Disorders and Stroke]

bulbarSubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Bulbar ALSFRS subscore. Sum of items: 1, 2 and 3.

cardiacDisease
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a cardiac disease.

cerebellarEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for cerebellar functions.

cerebellarRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the celebellar functions.

cerebralEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for cerebral functions.

cervicalSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a cervical spine surgery.

cervicalTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a cervical trauma.

clinicalTrialDescription
type: DatatypeProperty
domain: Clinical Trial
range: PlainLiteral
comment: The description of a clinical trial.

clinicallyEvaluatedEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: float
comment: Expanded Disability Status Score (EDSS) evaluated by the physician.

cognitiveRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the mental functions.

comorbiditySeverity
type: DatatypeProperty
type: FunctionalProperty
domain: Comorbidity
range: Datatype
  one of: life risk
  one of: moderate
  one of: serious
  one of: slight
comment: The severity of a comorbidity.

comorbidityTreatment
type: DatatypeProperty
domain: Comorbidity
range: PlainLiteral
comment: The treatment used for the comorbidity.

componentName
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: PlainLiteral
comment: The name of the hematopoietic component tested in the laboratory test result.

concentrationMeasurement
type: DatatypeProperty
domain: Air pollution concentration
range: float
comment: Raw air pollution concentration measured by the Sensing Device.

conditionEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Conditon
range: date
comment: The calendar date of the end of the registered prexisting conditon.

conditionStart
type: DatatypeProperty
type: FunctionalProperty
domain: Conditon
range: date
comment: The calendar date of the start of the registered prexisting conditon.

contiguousLesionsMRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected the presence of extended contiguous lesions equal to or greater than three vertical segments.

dailyCigarettes
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: integer
comment: The number of cigarettes smoked in one day on average.

deathCause
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007465
comment: The circumstance or condition that results in the death of a living being. [Definition Source: NCI]

deathDate
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: date
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1148348
comment: The calendar date of subject's death. [Definition Source: NCI]

dextricity
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0449722
comment: The preferred hand of use for controlled and efficient performance of motor tasks. [Definition Source: NCI]

diabetes
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had diabetes.

diagnosticCriteria
type: DatatypeProperty
type: FunctionalProperty
domain: Diagnosis
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0679228
comment: A standard from which a judgment concerning a medical diagnosis can be established. [Definition Source: NCI]

diet
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012155
comment: Regular course of eating and drinking adopted by a person or animal. [Definition Source: MSH]

dyslipidemia
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had dyslipidemia.

educationLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013658
comment: An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional schools. [Definition Source: NCI]

endReason
type: DatatypeProperty
domain: Clinical Trial Participation
range: PlainLiteral
comment: The reason for the interruption of the subject's participation in a clinical trial.

endTherapyReason
type: DatatypeProperty
type: FunctionalProperty
domain: End Therapy Reason
range: PlainLiteral
comment: The reason for the interruption of the therapeutic treatment.

eventEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Event
range: date
comment: The calendar date of the end of the event.

eventStart
type: DatatypeProperty
type: FunctionalProperty
domain: Event
range: date
comment: The calendar date of the start of the event.

evokedPotentialsLocation
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: left
  one of: lower
  one of: lower left
  one of: lower right
  one of: right
  one of: upper
  one of: upper left
  one of: upper right
comment: The body location of the evoked potential test.
note: Locations "upper left/upper right/lower left/lower right" can only be used for Evoked Potentials of type 'somatosensory' or 'motor'.

evokedPotentialsResponse
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: altered
  one of: normal
comment: The evoked potential function test result.

evokedPotentialsType
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: Datatype
  one of: auditory
  one of: motor
  one of: somatosensory
  one of: visual
comment: Whether the test was a Visual Evoked Potential (VEP), Auditory Evoked Potential (AEP), Somatosensory Evoked Potential (SSEP) or Motor Evoked Potential (MEP).

gadoliniumLesionsT1MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected some gadolinium-enhanced lesions in T1.

gadoliniumLesionsT1MRINumber
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: integer
comment: The number of gadolinium-enhanced lesions in T1.

generalizedOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced generalized onset, that are widespread symptoms.

genomeSequencing
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3640076
comment: A procedure that can determine the DNA sequence for nearly the entire genome of an individual. [Definition Source: NCI]

glucoseCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of blood sugar present in a sample of CSF. Unit of measure : [mg/l].

granulocytesCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The percentage of granulocytes present in a sample of CSF. Unit of measure : [%].

hadMajorTrauma
type: DatatypeProperty
domain: Before Onset
range: boolean
comment: Whether a patient had a major trauma before the disease onset.

hadSurgicalIntervention
type: DatatypeProperty
domain: Before Onset
range: boolean
comment: Whether the patient had a surgical intervention before the disease onset.

hasMutation
type: DatatypeProperty
type: FunctionalProperty
domain: Genetic Testing
range: boolean
comment: Whether the gene tested positive or negative for mutations during genetic testing.

headNeckSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a surgery in the head and neck area.

headTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an head trauma.

height
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0489786
comment: Distance or measurement from the base upwards; altitude; stature (of the human body). [Source: Oxford English Dictionary]

hypertension
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had hypertension.

immunoglobulinGCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of Immunoglobulin G (IgG) present in a sample of CSF. Unit of measure : [mg/l].

intensity
type: DatatypeProperty
domain: Physical Activity
range: PlainLiteral
comment: The level of intensity with which the physical activity is carried out.

kingsValue
type: DatatypeProperty
type: FunctionalProperty
domain: King's Clinical Staging Method
range: integer
comment: The patient's disease stage according to the King's Staging System.

lesionsT1MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected some lesions in T!.

leukocytesCountCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of leukocytes present in a sample of CSF. Unit of measure : [/mm3].

limbsOnset
type: DatatypeProperty
type: FunctionalProperty
domain: Onset
range: boolean
comment: Whether the patient experienced limb onset, which menas symptoms began in the arms or legs. [Definition Source: National Institute of Neurological Disorders and Stroke]

lowerLimbSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lower limb surgery.

lumboSacralSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lumbo sacral spine surgery.

lumboSacralTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a lumbo sacral trauma.

lymphocytesCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: The percentage of lymphocytes present in a sample of CSF. Unit of measure : [%].

maritalStatus
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024819
comment: A demographic parameter indicating a person's current conjugal status. [Definition Source: NCI]

measuredLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: float
comment: The level of the hematopoietic component measured in the laboratory test result.
note: This data property is populated only for numeric-valued test results.

measurementCalibrated
type: DatatypeProperty
domain: Air pollution concentration
range: float
comment: Air pollution concentration value with seasonal components and noise removed.

menopauseStatus
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3829127
comment: An indicator as to whether the female subject is in menopause. [Defintion source: NCI]

mitosValue
type: DatatypeProperty
type: FunctionalProperty
domain: Milano-Torino Functional Staging System (MiToS)
range: integer
comment: The patient's disease stage according to the MiToS staging system.

moreThan10PercentWeightloss
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: boolean
comment: Whether a patient lost more than 10% of his or her body weight.

motorSubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Motor ALSFRS subscore. Sum of items: 4, 5, 6, 7, 8 and 9.

multipleSclerosisType
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: clinically isolated syndrome (CIS)
  one of: primary progressive MS (PP)
  one of: radiologically isolated syndrome (RIS)
  one of: relapsing-remitting MS (RR)
  one of: secondary progressive MS (SP)
comment: The Multiple Sclerosis (MS) disease course identified in the patient.
note: This data property is used only for MS patients.

mutationType
type: DatatypeProperty
domain: Genetic Testing
range: PlainLiteral
comment: The type of mutation observed in the gene during genetic testing.

neckTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a neck trauma.

newOrEnlargedLesionsT2MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: boolean
comment: Whether the MRI detected new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

newOrEnlargedLesionsT2MRINumber
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: integer
comment: The number of new or enlarged gadolinium-enhanced lesions in T2 since the last MRI.

normalLevel
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: boolean
comment: Whether the measured level is within the normal range for the tested hematopoietic component.

notes
type: DatatypeProperty
domain: Patient
range: PlainLiteral
comment: An open box for adding notes about the patient.

oligoclonalBandsNumber
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: integer
comment: The number of oligoclonal bands present in the specimen.

oligoclonalBandsPresence
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: boolean
comment: Whether the tested specimen presents oligoclonal bands.

oligoclonalBandsType
type: DatatypeProperty
type: FunctionalProperty
domain: Oligoclonal Bands
range: Datatype
  one of: in CSF
  one of: in CSF & serum
comment: Whether the oligoclonal bands were found in CSF or in CSF & serum.

onsetElapsedTime
type: DatatypeProperty
type: FunctionalProperty
domain: Before Onset
range: Datatype
  one of: beyond 5years
  one of: within 5 yeras
comment: The time elapsed since the occurrence of an event that happened before the onset.

originalALSFRS
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items: 1,2,3,4,5,6,7,8,9 and old10.

otherOnset
type: DatatypeProperty
domain: Onset
range: PlainLiteral
comment: Other symptoms experienced by the patient during onset.

otherRelapse
type: DatatypeProperty
domain: Relapse
range: PlainLiteral
comment: Other functional systems involved in the relapse.

packYear
type: DatatypeProperty
type: FunctionalProperty
domain: Smoking
range: float
comment: Quantificator of lifetime tobacco exposure defined as: (number of cigarettes smoked per day) X (number of years smoked)/20.

participationEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: date
comment: The calendar date of the end of subject's partiicpation in a clinical trial.

participationStart
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Trial Participation
range: date
comment: The calendar date of the start of subject's partiicpation in a clinical trial.

pathologicalJCCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: boolean
comment: Whether the JC virus detected in the CSF specimen is pathological.
note: This data property can only be populated in "visuJCTestedCSF" has value True.

pelvicSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a pelivc surgery.

placeArea
type: DatatypeProperty
domain: Place
range: Datatype
  one of: city
  one of: rural
  one of: town
comment: The type of populated area that better describe the place.

positivityResult
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: boolean
comment: Whether the laboratory test result was positive or not.
note: This data property is only populated for positive/negative laboratory test result.

predominantLimbsImpairment
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: both
  one of: distal
  one of: proximal
comment: Whether the patient predominantly presents distal limbs impairment or proximal limbs impairment.
note: This data property is used only for ALS patients.

predominantLimbsSide
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: left
  one of: right
  one of: symmetric
comment: The side of the body that predominantly presents limb impariment.
note: This data property is used only for ALS patients.

predominantMotorNeuron
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: Datatype
  one of: both motor neuron
  one of: lower motor neuron
  one of: upper motor neuron
comment: Whether the patient presents a predominance of lower motor neuron, upper motor neuron or both.
note: This data property is used only for ALS patients.

pregnancyComplications
type: DatatypeProperty
domain: Pregnancy
range: PlainLiteral
comment: Any kind of complication related to the pregnancy.

pregnancyEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: date
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3173355
comment: The calendar date in which the pregnancy ended.

pregnancyEndEvent
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: PlainLiteral
comment: The event that ended the pregnancy.

pregnancyStart
type: DatatypeProperty
type: FunctionalProperty
domain: Pregnancy
range: date
comment: The calendar date in which the pregnancy started.

primaryNeoplasm
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a primary neoplasm.

procedureEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Intervention or Procedure
range: date
comment: The calendar date of the end of an intervention or procedure.

procedureStart
type: DatatypeProperty
type: FunctionalProperty
domain: Intervention or Procedure
range: date
comment: The calendar start of an intervention or procedure.

proteinsCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: A quantitative measurement of proteins present in a sample of CSF [ mg/l].

pulmonaryAOPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Occlusion pressure at 100 ms (P0.1) is defined as the negative pressure measured 100 ms after the initiation of an inspiratory effort performed against a closed respiratory circuit. [Definition Source: Beloncle, F., Piquilloud, L., Olivier, PY. et al. Accuracy of P0.1 measurements performed by ICU ventilators: a bench study. Ann. Intensive Care 9, 104 (2019)]

pulmonaryFEV6
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Forced expiratory volume (FEV) is the amount of air expired in six seconds of the FVC test. [Definition Source: John Hopkins Medicine]

pulmonaryFVCRel
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The percentage of Forced vital capacity (FVC) is the amount of air exhaled forcefully and quickly after inhaling as much as you can. [Defintion Source: John Hopkins Medicine]

pulmonaryMEPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Expiratory Pressure (MEP) is the highest pressure that can be developed during a forceful expiratory effort against an occluded airway. It is usually measured at maximal inspiration and reported as a positive number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

pulmonaryMIPAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Maximum Inspiratory Pressure (MIP) is the lowest pressure developed during a forceful inspiration against an occluded airway. It is usually measured at maximal expiration and recorded as a negative number in either cm H2O or mmHg. [Definition Source: The University of Texas Medical Branch]

pulmonaryPCO2
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The partial pressure of carbon dioxide (PCO2) is the concentration of carbon dioxide in the blood. This is a sensitive indication of the efficiency or level of ventilation of the lungs. [Definition Source: Collins Dictionary of Medicine]

pulmonaryPO2
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: The partial pressure of oxigen (PO2) is the concentration of oxygen in the blood. This commonly measured parameter is an important indicator of the efficiency with which oxygen is transferred from atmosphere to blood. [Definition Source: Collins Dictionary of Medicine]

pulmonaryVCAbs
type: DatatypeProperty
type: FunctionalProperty
domain: Pulmonary Function Test
range: float
comment: Vital capacity (VC) is the total volume of air that can be exhaled after inhaling as much as you can. [Definition Source: John Hopkins Medicine]

pyramidalEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for pyramidal functions.

pyramidalRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved the pyramidal functions.

quotientAlbuminCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: float
comment: CSF/serum albumin ratio is performed to understand the blood–CSF barrier disruption. [Defintion Source: Luque, Francisco A, and Stephen L Jaffe. “Cerebrospinal fluid analysis in multiple sclerosis.” International review of neurobiology vol. 79 (2007)]

relapseClinicalTherapy
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required treatment in an ambulatory care clinic.

relapseCortisoneTherapy
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required a cortisone therapy.

relapseDuration
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: integer
comment: The number of days the relapse lasted.

relapseEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: date
comment: The calendar date of the end of the relapse.

relapseHospitalAdmission
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse required an hospital admission.

relapseImpactOnADL
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse afftecd the Activity of Daily Living (ADL).

relapseRecovery
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: Datatype
  one of: complete
  one of: none
  one of: partial
comment: How much the patient recovered from the relapse.

relapseSequela
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the patient presented symptoms continuing in time, maybe less severe.

relapseSeverity
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: Datatype
  one of: life risk
  one of: moderate
  one of: serious
  one of: slight
comment: The severity of the relapse.

relapseStart
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: date
comment: The calendar date of the start of the relapse.

residenceEnd
type: DatatypeProperty
type: FunctionalProperty
domain: Residence
range: date
comment: The calendar end date of the patient's residence in a specific geographical location.

residenceStart
type: DatatypeProperty
type: FunctionalProperty
domain: Residence
range: date
comment: The calendar start date of the patient's residence in a specific geographical location.

respiratorySubscore
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
comment: Respiratory ALSFRS subscore. Sum of items: 10, 11 and 12.

retiredAtDiagnosis
type: DatatypeProperty
type: FunctionalProperty
domain: Patient
range: boolean
comment: An indicator of whether the patient was retired at the time of diagnosis.

revisedALSFRS
type: DatatypeProperty
type: FunctionalProperty
domain: Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4296567
comment: Revised Amyotrophic Lateral Sclerosis Functional Rating Scale. Sum of items 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12.

sensoryEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for sensory functions.

sensoryRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved sensory functions.

sex
type: DatatypeProperty
type: FunctionalProperty
domain: Person
range: Datatype
  one of: female
  one of: male
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522384
comment: The assemblage of physical properties or qualities by which male is distinguished from female; the physical difference between male and female; the distinguishing peculiarity of male or female. [Definition Source: NCI]

sexuality
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036915
comment: The feeling an individual has about their own sexual preferences and how those views are acted upon. [Definition Source: NCI]

stroke
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a stroke.

sunExposure
type: DatatypeProperty
type: FunctionalProperty
domain: Lifestyle
range: integer
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1456711
comment: The exposure to incident light from the sun. [Definition Source: NCI]

thoracicSpineSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic spine surgery.

thoracicSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic surgery.

thoracicTrauma
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had a thoracic trauma.

thyroidDisorder
type: DatatypeProperty
domain: ALS Brainteaser Comorbidities
range: boolean
comment: Whether a patient ever had a thyroid disorder.

totalLesionsT2MRI
type: DatatypeProperty
type: FunctionalProperty
domain: Magnetic Resonance Imaging (MRI)
range: PlainLiteral
comment: The total number of lesions in T2 detected with the MRI.

traumaDate
type: DatatypeProperty
type: FunctionalProperty
domain: Trauma
range: date
comment: The calendar date in which the trauma occurred.

traumaDescription
type: DatatypeProperty
domain: Trauma
range: PlainLiteral
comment: A description of the trauma

unitOfMeasure
type: DatatypeProperty
type: FunctionalProperty
domain: Laboratory Test Result
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1519795
comment: The unit of measure of reference of the laboratory test result.

upperLimbSurgery
type: DatatypeProperty
domain: Class
  union of: Last 5 Years Event
  union of: More Than 5 Years Event
range: boolean
comment: Whether a patient had an upper limb surgery.

virusJCTestedCSF
type: DatatypeProperty
type: FunctionalProperty
domain: CSF Analysis
range: boolean
comment: Whether the presence of JC virus was tested in the CSF specimen.

visualEDSS
type: DatatypeProperty
type: FunctionalProperty
domain: Expanded Disability Status Scale (EDSS)
range: integer
comment: Expanded Disability Status Score (EDSS) score for visual (optic) functions.

visualEvokedPotentialAmplitude
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: float
comment: The amplitude for the Visual Evoked Potential (VEP) wave. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [uV].
note: This data property can only be used for Evoked Potential of type 'visual'.

visualEvokedPotentialLatency
type: DatatypeProperty
type: FunctionalProperty
domain: Evoked Potentials
range: integer
comment: The average peak latency for the Visual Evoked Potential (VEP) wave at approximately 100 ms following stimulus onset. [Source: Wikipedia - consulted on November 25th, 2022] Unit of Measure: [microsec].
note: This data property can only be used for Evoked Potential of type 'visual'.

visualRelapse
type: DatatypeProperty
type: FunctionalProperty
domain: Relapse
range: boolean
comment: Whether the relapse involved visual functions.

weeklyFrequency
type: DatatypeProperty
domain: Physical Activity
range: integer
comment: The number of times per week physical activity takes place.

weight
type: DatatypeProperty
type: FunctionalProperty
domain: Clinical Evaluation
range: float
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005910
comment: Measurement of quantity by means of weighing; quantity (in the abstract) as determined in this way. [Definition Source: Oxford English Dictionary]

zipCode
type: DatatypeProperty
type: FunctionalProperty
domain: Place
range: PlainLiteral
comment: A group of letters or numbers, or both, added to a postal address to facilitate the sorting and delivery of mail. Later also: the area designated by such a code. [Definition Source: Oxford English Dictionary]

zipHashed
type: DatatypeProperty
type: FunctionalProperty
domain: Place
range: PlainLiteral
comment: The zip code hashed for privacy reasons.

betweenessCentralityCoefficient
type: DatatypeProperty
domain: Cognitive Assessment
range: float
comment: The coefficient of betweeness centrality for connectivity tests.

bloodGasPCO2
type: DatatypeProperty
domain: Blood Gas Analysis
range: float
comment: The level of PCO2 in the blood.

bloodGasPH
type: DatatypeProperty
domain: Blood Gas Analysis
range: float
comment: The pH of the blood.

bloodGasPO2
type: DatatypeProperty
domain: Blood Gas Analysis
range: float
comment: The level of PO2 in the blood.

bloodGasSO2
type: DatatypeProperty
domain: Blood Gas Analysis
range: float
comment: The level of SO2 in the blood.

clusteringCoefficient
type: DatatypeProperty
domain: Cognitive Assessment
range: float
comment: The coefficient of clustering for connectivity tests.

conductionBlocks
type: DatatypeProperty
domain: Electromyography
range: boolean
comment: Presence of conduction blocks on electromyography.

electricTraumaRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to electric trauma.

electromyographyOutcome
type: DatatypeProperty
domain: Electromyography
range: PlainLiteral
comment: The outcome of the electromyography test.

emotionalLiability
type: DatatypeProperty
domain: Clinical Evaluation
range: boolean
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085633
comment: Boolean data property stating whether the patient experienced emotional liability during the visit.

everSmoked
type: DatatypeProperty
domain: Patient
range: boolean
comment: Whether a patient has ever smoked.

formatDKEFS
type: DatatypeProperty
domain: Delis-Kaplan Executive Function System (D-KEFS)
range: PlainLiteral
comment: The format of the Delis-Kaplan Executive Function System (D-KEFS)

furtherRelapseBeforePL
type: DatatypeProperty
domain: Relapse
range: boolean
comment: Further relapse before plasmapheresis (PL): A treatment that removes harmful antibodies from the blood.

globalCoefficient
type: DatatypeProperty
domain: Cognitive Assessment
range: float
comment: The global coefficient for connectivity tests.

herbicidesRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to herbicides.

hoffmanLeft
type: DatatypeProperty
domain: Hoffman's Reflex Test
range: PlainLiteral
comment: Hoffman's Reflex on the left side.

hoffmanRight
type: DatatypeProperty
domain: Hoffman's Reflex Test
range: PlainLiteral
comment: Hoffman's Reflex on the right side.

leftPlantarReflex
type: DatatypeProperty
domain: Plantar Reflex Test
range: PlainLiteral
comment: Cutaneous-Plantar Reflex of the left foot.

lowerLimbsTendonReflex
type: DatatypeProperty
domain: Tendon Reflex Test
range: PlainLiteral
comment: Tendon Reflex of the lower limbs

massetericReflex
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Clinical assessment of the masseteric reflex.

metalsRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to metals.

methodCSF
type: DatatypeProperty
domain: CSF Analysis
range: Datatype
  one of: Old
  one of: SEBIA
comment: CSF analysis method.

msDiagnosis2010Criteria
type: DatatypeProperty
domain: Diagnosis
range: Datatype
  one of: Relapsing Remitting Multiple Sclerosis (RRMS)
comment: Diagnosis following 2010 criteria

muscleAtrophy
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Clinical assessment of muscle atrophy.

muscleTone
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Clinical assessment of muscle tone.

muscleBiopsyOutcome
type: DatatypeProperty
domain: Muscle Biopsy
range: PlainLiteral
comment: Outcome of the muscle biopsy.

performedCSF
type: DatatypeProperty
domain: CSF Analysis
range: boolean
comment: Whether a CSF analysis was performed.

performedCSFAnalysis
type: DatatypeProperty
domain: CSF Analysis
range: boolean
comment: Whether the CSF analysis was performed.

performedMuscleBiopsy
type: DatatypeProperty
domain: Muscle Biopsy
range: boolean
comment: Whether the muscle biopsy was performed.

pesticidesRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to pesticides.

petOutcome
type: DatatypeProperty
domain: Positron Emission Tomography (PET)
range: PlainLiteral
comment: The outcome of the PET scan.

polioRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to poliomyelitis.

raoClassification
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Rao's classification divides lesions into four types: • Type I: Hyperintense lesions only on T2. • Type II: Lesions isointense on T1, hyperintense on T2, without enhancement. • Type III: Lesions isointense on T1, hyperintense on T2, with incomplete enhancement in the shape of an open ring. • Type IV: Lesions isointense on T1, hyperintense on T2, with complete enhancement in the shape of a closed ring.

rightPlantarReflex
type: DatatypeProperty
domain: Plantar Reflex Test
range: PlainLiteral
comment: Cutaneous-Plantar Reflex of the right foot.

Questionnaire's score reported by a patient.
type: DatatypeProperty
domain: Class
  union of: Multiple Scleroris Neuropsychological Questionnaire (MSNQ)
  union of: Self-Reported Questionnaire
range: float
label: selfReportedScore

solventsRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated with solvents.

sportRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to sport.

tongueAtrophy
type: DatatypeProperty
domain: Neurologic Exam
range: PlainLiteral
comment: Wasting of the tongue. [Definition Source: HPO]

tongueFasciculation
type: DatatypeProperty
domain: Neurologic Exam
range: PlainLiteral
comment: Fasciculations or fibrillation affecting the tongue muscle. [Definition Source: HPO]

tongueNotProtruding
type: DatatypeProperty
domain: Neurologic Exam
range: PlainLiteral
comment: Tongue not extending beyond the alveolar ridges or teeth at rest. [PMID:19125428]

tongueProtrusion
type: DatatypeProperty
domain: Neurologic Exam
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0241442
comment: Tongue extending beyond the alveolar ridges or teeth at rest. [PMID:19125428]

tongueThrust
type: DatatypeProperty
domain: Neurologic Exam
range: PlainLiteral
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1829460
comment: Pressing forward of the tongue in the mouth, a retained motoric habit from infantile swallowing patterns [PMID:34413610]

traumaRisk
type: DatatypeProperty
domain: Risk Factor
range: boolean
comment: Risk factor associated to trauma.

upperLimbsMobility
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Clinical assessment of upper limbs mobility and coordination.

upperLimbsTendonReflex
type: DatatypeProperty
domain: Tendon Reflex Test
range: PlainLiteral
comment: Tendon Reflex test for the upper limbs.

urinaryUrgency
type: DatatypeProperty
domain: Clinical Evaluation
range: boolean
comment: Boolean property stating whether the patient had urinary urgency during the visit.

urinaryUrgencyTherapy
type: DatatypeProperty
domain: Clinical Evaluation
range: boolean
comment: Boolean property stating whether the patient follows urinary urgency therapy.

walkEvaluation
type: DatatypeProperty
domain: Clinical Evaluation
range: PlainLiteral
comment: Clinical assessment of walking ability.

Person
type: Class
comment: A human being. [Definition Source: NCI]

ALS Brainteaser Comorbidities
type: Class
subclass of: Use-Case Comorbidities
comment: Comorbidities checked for ALS patient in the BRAINTEASER study.

Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS)
type: Class
subclass of: Questionnaire
comment: The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) is an instrument for evaluating the functional status of patients with Amyotrophic Lateral Sclerosis. It can be used to monitor functional change in a patient over time. [Definition Source: Georgetown University Hospital - Medstar Health]

Activity
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0441655
comment: An active process; excludes processes and mechanisms which fulfill biological functions. [Definition Source: NCI]
note: In our data we refer to it as "Behaviour".

Administration
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1533734
comment: The act of the dispensing, applying, or tendering of something to another, such as administration of a medicine. [Definition Source: NCI]

Adverse Drug Reaction
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0041755
comment: Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCI]

Anatomic Site
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1515974
comment: Named locations of or within the body. [Definition Source: NCI]

Before Onset
type: Class
subclass of: Event
comment: Any event that happened to a patient before the onset.

CO concentration
type: Class
subclass of: Air pollution concentration
comment: The determination of the amount of carbon monoxide present in a sample. [Definition Source: NCI]

CSF Analysis
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2026522
comment: A laboratory analysis of a sample of cerebrospinal fluid. [Definition Source: NCI]

Clinical Evaluation
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1261322
comment: An assessment of an individual's physical, mental, or emotional condition; information can be gathered from multiple sources, including physical exam, personal interview and observation, medical history, laboratory and imaging tests. [Definition Source: NCI]

Clinical Trial
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008976
comment: A research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes. [Definition Source: NCI]

Clinical Trial Participation
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4041024
comment: The participation in a clinical trial

Clinics and Hospitals
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0587906
comment: Institutions with an organized medical staff for the medical care, treatment, and cure of the sick and wounded, for the study of disease, and for the training of physicians, nurses, and allied health personnel. [Definition Source: NCI]

Comorbidity
type: Class
subclass of: Conditon
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009488
comment: The coexistence of two or more disease processes. [Definition Source: NCI]

Conditon
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0348080
comment: A state of being, such as a state of health. [Definition Source: NCI]

Diagnosis
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011900
comment: The investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms; also, the scientific determination of any kind; the concise results of such an investigation. [Definition Source: NCI]

Diagnostic Imaging
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011923
comment: Any method that uses a visual display of structural or functional patterns of organs or tissues for diagnostic evaluation. [Definition Source: NCI]

Diagnostic Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0430022
comment: Any procedure or test to diagnose a disease or disorder. [Definition Source: NCI]

Disease, Disorder or Finding
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1511989
comment: A condition that is relevant to human neoplasms and non-neoplastic disorders. This includes observations, test results, history and other concepts relevant to the characterization of human pathologic conditions. [Definition Source: NCI]

Expanded Disability Status Scale (EDSS)
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0451246
comment: A system for quantifying disability in multiple sclerosis (MS). Based on a standard neurological examination, the Expanded Disability Status Scale quantifies disability in seven Functional Systems (plus "Other") and assigns a Functional System Score in each. Results are ranked as steps from 0 to 10, with steps 1 through 4.5 describing MS patients who are fully ambulatory and steps 5 through 9.5 describing increasing impairment to ambulation. Step 10 refers to death due to MS. [Definition Source: NCI]

End Therapy Reason
type: Class
comment: The motivation for the interruption of the therapeutic treatment.

Event
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0441471
comment: Something that happens at a given place and time. [Definition Source: NCI]

Evoked Potentials
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015214
comment: Electrical responses recorded from nerve, muscle, SENSORY RECEPTOR, or area of the CENTRAL NERVOUS SYSTEM following stimulation. They range from less than a microvolt to several microvolts. The evoked potential can be auditory (EVOKED POTENTIALS, AUDITORY), somatosensory (EVOKED POTENTIALS, SOMATOSENSORY), visual (EVOKED POTENTIALS, VISUAL), or motor (EVOKED POTENTIALS, MOTOR), or other modalities that have been reported. [Definition Source: MSH]

Gene
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017337
comment: A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCI]

Genetic Testing
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0679560
comment: The process of isolating and testing the DNA of an embryo or a person to detect the presence of genetic alterations or defects that may predispose to the future development of a disease or disorder. [Definition Source: NCI]

Group (social concept)
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1257890
comment: A group of individuals united by a common factor (e.g., geographic location, ethnicity, disease, age, gender) [Definition Source: NCI]

Hematology Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0200627
comment: A laboratory test to measure hematopoietic components and investigate hematologic disorders in a blood sample. [Definition Source: NCI]

Impairment
type: Class
subclass of: Conditon
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0221099
comment: Loss or abnormality of psychological, physiological, or anatomic structure or function. [Definition Source: NCI]

Intervention or Procedure
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0184661
comment: An activity that produces an effect, or that is intended to alter the course of a disease in a patient or population. This is a general term that encompasses the medical, social, behavioral, and environmental acts that can have preventive, therapeutic, or palliative effects. [Definition Source: NCI]

King's Clinical Staging Method
type: Class
subclass of: Questionnaire
comment: The King’s staging system consists of five disease stages, with Stage 5 being death. Stages 1–3 are based upon the number of El Escorial central nervous system (CNS) regions involved in the disease, measured by weakness, wasting, spasticity, dysphagia, or dysarthria. Stage 4 is nutritional failure, defined by the requirement for gastrostomy, or respiratory failure, defined by the requirement for noninvasive ventilation (NIV), and based upon the National Institute for Clinical Excellence MND Guidelines (Supplemental Material). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]

Kinship
type: Class
comment: The relationship between members of the same family. [Cambridge Dictionary]
note: This class is always instantiated as a blank node

KinshipType
type: Class
comment: The type of the relationship between members of the same family.
note: For the purpose of our ontology, we only consider biological kinship. We omit the word "biological" from the invidual's labels, for example "father" refers to "biological father".

Laboratory Test Result
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0587081
comment: The outcome of a laboratory test. [Definition Source: NCI]

Last 5 Years Event
type: Class
subclass of: Before Onset
comment: Events occurred in the last 5 years (from the first visit).

Lifestyle
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023676
comment: A manner of living that reflects the person's values and attitudes. [Definition Source: NCI]

Magnetic Resonance Imaging (MRI)
type: Class
subclass of: Diagnostic Imaging
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024485
comment: Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders. [Definition Source: NCI]

Milano-Torino Functional Staging System (MiToS)
type: Class
subclass of: Questionnaire
comment: The Milano–Torino (MiToS) Staging system comprises six stages, based on functional impairment as assessed by the revised ALS Functional Rating Scale (ALSFRS-R). [Definition Source: Balendra, Rubika et al. “A standard operating procedure for King's ALS clinical staging.” Amyotrophic lateral sclerosis & frontotemporal degeneration vol. 20,3-4 (2019): 159-164.]

More Than 5 Years Event
type: Class
subclass of: Before Onset
comment: Events occured more than 5 years ago, counting from the first visit.

Occupation
type: Class
comment: The principal activity that a person does to earn money. [Definition Source: NCI]

Oligoclonal Bands
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4048246
comment: The presence of more than one immunoglobulin band in the serum, urine, or cerebrospinal fluid. It usually results from infectious or immunologic disorders. [Definition Source: NCI]

Onset
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0332162
comment: The start, beginning, or early stages. [Definition Source: NCI]

Positron Emission Tomography (PET)
type: Class
subclass of: Diagnostic Imaging
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032743
comment: A technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered. [Definition Source: NCI]

Patient
type: Class
subclass of: Person
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030705
comment: A person who receives medical attention, care, or treatment, or who is registered with medical professional or institution with the purpose to receive medical care when necessary. [Definition Source: NCI]

Pharmacologic Substance
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1254351
comment: Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCI]

Physical Activity
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026606
comment: Any form of exercise or movement. Physical activity may include planned activity such as walking, running, basketball, or other sports. Physical activity may also include other daily activities such as household chores, yard work, walking the dog, etc. [Definition Source: NCI][attribution: from NIDDK Glossary; http://www.niddk.nih.gov/health/nutrit/pubs/glossary/glossaryintro.htm]

Place
type: Class
comment: A particular part or region of space; a physical locality, a locale; a spot, a location. [Definition Source: Oxford English Dictionary]

Pregnancy
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032961
comment: The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. [Definition Source: NCI]

Protocol Event
type: Class
subclass of: Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2698908
comment: Other important events that occur during a trial but are not driven by protocol requirements. [Definition Source: NCI]

Pulmonary Function Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024119
comment: A broad range of tests that are performed to assess how well lungs inhale and exhale air and how efficiently they transfer oxygen into the blood. [Definition Source: NCI]

Questionnaire
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034394
comment: A predetermined set of questions. [Definition Source: NCI]

Relapse
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0277556
comment: The return of a disease after a period of remission. [Definition Source: NCI]

Residence
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0237096
comment: Any address at which a person dwells more than temporarily. [Definition Source: NCI]

Smoking
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037369
comment: The act of puffing and/or inhaling the combustion products of a substance so as to be tasted and absorbed into the bloodstream. [Definition Source: NCI]

Surgical Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0543467
comment: A diagnostic or treatment procedure performed by manual and/or instrumental means, often involving an incision and the removal or replacement of a diseased organ or tissue; of or relating to or involving or used in surgery or requiring or amenable to treatment by surgery. [Definition Source: NCI]

Surgical Procedure Type
type: Class
comment: It defines some type of surgical procedures a patient could undergo.

Therapeutic Procedure
type: Class
subclass of: Intervention or Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0087111
comment: An action or administration of therapeutic agents to produce an effect that is intended to alter or stop a pathologic process. [Definition Source: NCI]

Therapeutic Procedure Type
type: Class
comment: It defines some type of therapeutic procedures that could be administered to a patient.

Therapeutic Treatment
type: Class
comment: The therapeutic treatment that has been administered to a patient.

Trauma
type: Class
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3263723
comment: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]

Use-Case Comorbidities
type: Class
subclass of: Comorbidity
comment: Comorbidities checked in a specific use-case, e.g. ALS patients in a specific study.

Local Health Autority
type: Class
comment: A Local Health Authority (Italian: azienda sanitaria locale), commonly abbreviated as ASL in Italian, or a Local Health Unit Authority, known as AUSL, is a public organization that falls under the purview of the Italian public administration. Its primary mandate is to deliver healthcare services to a specific territorial area, which is typically at the provincial level. In different regions of Italy, these entities are referred to by various designations, including ASP, ASM, ATS, and AST.

Company-Socio-Health Local Autority
type: Class
subclass of: Local Health Autority
comment: The Local Health Autority denomination in Veneto.

Beck Depression Inventory-II (BDI-II)
type: Class
subclass of: Self-Reported Questionnaire
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4696539
comment: BDI-II (Beck Depression Inventory-II) is a self-report questionnaire used to assess the severity of depression in multiple sclerosis patients. By analyzing BDI-II scores alongside brain connectivity metrics, researchers can explore how depression severity relates to brain network organization and function in individuals with MS.

Blood Gas Analysis
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005800
comment: Measurement of oxygen and carbon dioxide in the blood. [Definition Source: MSH]

Corpus Callosum Topography Score (CLTR)
type: Class
subclass of: Cognitive Assessment
comment: CLTR (Corpus Callosum Topography Score) quantifies lesion load and distribution within the corpus callosum of multiple sclerosis patients. By analyzing CLTR alongside brain connectivity metrics, researchers can assess how callosal damage affects inter-hemispheric communication efficiency and its impact on cognitive function.

Cognitive Assessment
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0870300
comment: The examination of the cognitive capacities or deficits of an individual through the application of tests that probe that individual's ability to perform various mental activities such as perception, learning, and reasoning. [Definition Source: NCI]

Delis-Kaplan Executive Function System (D-KEFS)
type: Class
subclass of: Cognitive Assessment
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4065492
comment: The Delis–Kaplan Executive Function System (D-KEFS) is a neuropsychological test used to measure a variety of verbal and nonverbal executive functions for both children and adults (ages 8–89 years). [Definition Source: Wikipedia]

Delis-Kaplan Executive Function System Color-Word Interference Switching Condition (D-KEFS FSC)
type: Class
subclass of: Delis-Kaplan Executive Function System (D-KEFS)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4065470
comment: D-KEFS FSC (Delis-Kaplan Executive Function System Color-Word Interference Switching Condition) assesses cognitive flexibility and switching ability in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics researchers can identify how MS affects brain networks involved in executive function and task switching.

Delis-Kaplan Executive Function System Design Fluency Condition (D-KEFS FSD)
type: Class
subclass of: Delis-Kaplan Executive Function System (D-KEFS)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4065432
comment: D-KEFS FSD (Delis-Kaplan Executive Function System Design Fluency Condition) assesses creativity and the ability to generate novel ideas in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics, researchers can identify how MS affects brain networks involved in creative thinking and fluency.

Delis-Kaplan Executive Function System Sorting Test - Free Sort & Sort Recognition (D-KEFS SR)
type: Class
subclass of: Delis-Kaplan Executive Function System (D-KEFS)
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4065401
comment: D-KEFS SR (Delis-Kaplan Executive Function System Sorting Test - Free Sort & Sort Recognition) assesses problem-solving, abstract thinking, and cognitive flexibility in multiple sclerosis patients. By analyzing performance alongside brain connectivity metrics, researchers can identify how MS affects brain networks involved in these cognitive processes.

Electromyography
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013839
comment: An assessment of skeletal muscle function and nerve control, obtained by recording and studying the intrinsic electrical properties of the muscles. [Defintion Source: NCI]

Fatigue Severity Score (FSS)
type: Class
subclass of: Self-Reported Questionnaire
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3813323
comment: FSS (Fatigue Severity Scale) is a patient-reported questionnaire used to assess the impact of fatigue on daily life in multiple sclerosis. Analyzing FSS scores alongside brain connectivity metrics can help understand how MS-related brain changes relate to fatigue severity and the efficiency of relevant brain networks.

Hoffman's Reflex Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0277839
comment: A Hoffmann test is performed by flicking the fingernail of the long finger, from dorsal to volar, on each hand while the hand was supported by the examiner's hand. The test was done with the neck in the neutral position and then with the neck maximally forward flexed. Any flexion of the ipsilateral thumb and/or index finger was interpreted as a positive test. [PMID:11813951, PMID:20229121]

Lesion Topography Score (LTS)
type: Class
subclass of: Cognitive Assessment
comment: LTS (Lesion Topography Score) quantifies lesion distribution in the brains of multiple sclerosis patients. By examining LTS alongside brain connectivity metrics, researchers can assess how lesion location and extent affect brain network organization and communication efficiency, potentially influencing cognitive and motor function.

Multiple Scleroris Neuropsychological Questionnaire (MSNQ)
type: Class
subclass of: Questionnaire
comment: MSNQ (Multiple Sclerosis Neuropsychological Questionnaire) assesses cognitive and emotional aspects of life with multiple sclerosis, such as memory, attention, and depression. Analyzing MSNQ scores alongside brain connectivity metrics can provide insights into how MS-related brain changes impact self-reported cognitive and emotional functioning.

Muscle Biopsy
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0185283
comment: Removal of a small piece of muscle tissue for examination.

Neurologic Exam
type: Class
subclass of: Diagnostic Procedure
conforms to: http://purl.bioontology.org/ontology/SNOMEDCT/225398001
comment: The assessment of the functionality of the brain, spinal column, and nerves. [Definition Source: NCI]

Paced Auditory Serial Addition Test (PASAT)
type: Class
subclass of: Cognitive Assessment
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3898036
comment: PASAT (Paced Auditory Serial Addition Test) assesses information processing speed and calculation ability in multiple sclerosis patients. By correlating PASAT scores with brain connectivity metrics, researchers can identify how MS affects brain networks involved in attention,working memory, and cognitive processing.

Plantar Reflex Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0278131
comment: Test of the cutaneous-plentar reflex.

Risk Factor
type: Class
subclass of: Activity
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035648
comment: Any aspect of an individual's life, behavior, an environmental exposure, or an inborn or inherited characteristic that increases the likelihood of a disease, condition or injury. [Definition Source: NCI]

Symbol Digit Modalities Test (SDMT)
type: Class
subclass of: Cognitive Assessment
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3891405
comment: Symbol Digit Modalities Test. It is a neuropsychological test used to assess cognitive function, particularly attention,visual scanning, and motor speed. The SDMT involves matching symbols with numbers under a time constraint.

Spatial Recall Test (SPART)
type: Class
subclass of: Cognitive Assessment
comment: SPART (Spatial Recall Test) assesses spatial learning and memory in multiple sclerosis patients by evaluating their ability to recall the location of objects on a board. Combining SPART scores with brain connectivity metrics can reveal how MS affects spatial memory networks and their efficiency, integration, and role in information flow.

Symbol Digit Modalities Test - Delayed (SPART-D)
type: Class
subclass of: Cognitive Assessment
comment: SPART-D: Symbol Digit Modalities Test – Delayed (delayed recall version of the SPART)

Selective Reminding Test - Delayed
type: Class
subclass of: Cognitive Assessment
comment: SRT-D (Selective Reminding Test – Delayed) assesses long-term verbal memory in multiple sclerosis patients by evaluating their ability to recall a word list after a delay. Combining SRT-D scores with brain connectivity metrics can reveal how MS affects memory consolidation and retrieval networks, and the efficiency of information flow within these networks.

Self-Reported Questionnaire
type: Class
subclass of: Questionnaire
comment: A questionnaire reported by the patient.

Tendon Reflex Test
type: Class
subclass of: Diagnostic Procedure
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034943
comment: Tendon Reflex Test

Word List Generation (WLG)
type: Class
subclass of: Cognitive Assessment
comment: WLG: Word List Generation (a measure of verbal fluency)

Armed forces occupations
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Armed forces occupations include all jobs held by members of the armed forces. Members of the armed forces are those personnel who are currently serving in the armed forces, including auxiliary services, whether on a voluntary or compulsory basis, and who are not free to accept civilian employment and are subject to military discipline. Included are regular members of the army, navy, air force and other military services, as well as conscripts enrolled for military training or other service for a specified period. Occupations in this major group are classified into the following sub-major groups: 01 Commissioned Armed Forces Officers 02 Non-commissioned Armed Forces Officers 03 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.

Commissioned armed forces officers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Armed forces occupations
in scheme: Occupation Taxonomy
comment: Commissioned armed forces officers provide leadership and management to organizational units in the armed forces and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes all members of the armed forces holding the rank of second lieutenant (or equivalent) or higher. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 011 Commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.

Non-commissioned armed forces officers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Armed forces occupations
in scheme: Occupation Taxonomy
comment: Non-commissioned armed forces officers enforce military discipline and supervise the activities of those employed in Sub-major Group 03: Armed Forces Occupations, Other Ranks, and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. This group includes members of the armed forces holding ranks such as sergeant, warrant officer and sergeant major. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 021 Non-commissioned Armed Forces Officers Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.

Armed forces occupations, other ranks
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Armed forces occupations
in scheme: Occupation Taxonomy
comment: Armed forces occupations, other ranks include all conscripted and non-conscripted members of the armed forces except commissioned and non-commissioned officers. They perform specific military tasks and/or perform similar tasks to those performed in a variety of civilian occupations outside the armed forces. Most occupations in this sub-major group require skills at the first ISCO skill level. Occupations in this sub-major group are classified into the following minor group: 031 Armed Forces Occupations, Other Ranks Excluded from this group are: - jobs held by persons in civilian employment of government establishments concerned with defence issues; - police (other than military police); - customs inspectors and members of border or other armed civilian services.

Managers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Managers plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations, or of organizational units within them, and formulate and review their policies, laws, rules and regulations. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level, except for Sub-major Group 14: Hospitality, Retail and Other Services Managers, for which skills at the third ISCO skill level are generally required. Tasks performed by managers usually include: formulating and advising on the policy, budgets, laws and regulations of enterprises, governments and other organizational units; establishing objectives and standards and formulating and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise and of its staff; selecting or approving the selection of staff; ensuring compliance with health and safety requirements; planning and directing daily operations; representing and negotiating on behalf of the government, enterprise or organizational unit managed in meetings and other forums. Occupations in this major group are classified into the following sub-major groups: 11 Chief Executives, Senior Officials and Legislators 12 Administrative and Commercial Managers 13 Production and Specialized Services Managers 14 Hospitality, Retail and Other Services Managers

Chief executives, senior officials and legislators
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Managers
in scheme: Occupation Taxonomy
comment: Chief executives, senior officials and legislators formulate and review the policies, and plan, direct, coordinate and evaluate the overall activities of enterprises, governments and other organizations with the support of other managers. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level . Tasks performed by workers in this sub-major group usually include: presiding over or participating in the proceedings of legislative bodies, boards of directors and committees; formulating and advising on the policy budgets, laws and regulations of enterprises, governments and other organizations; establishing objectives for enterprises, government departments or agencies and other organizations; formulating or approving and evaluating programmes and policies and procedures for their implementation; ensuring appropriate systems and procedures are developed and implemented to provide budgetary control; authorizing material, human and financial resources to implement policies and programmes; monitoring and evaluating performance of the organization or enterprise; selecting or approving the selection of senior staff; performing ceremonial duties and representing the enterprise, government, organization or community at official occasions and in meetings, negotiations, conventions and public hearings. Occupations in this sub-major group are classified into the following minor groups: 111 Legislators and Senior Officials 112 Managing Directors and Chief Executives

Administrative and commercial managers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Managers
in scheme: Occupation Taxonomy
comment: Administrative and commercial managers plan, organize, direct, control and coordinate the financial, administrative, human resource, policy, planning, research and development, advertising, public relations, and sales and marketing activities of enterprises and organizations, or of enterprises that provide such services to other enterprises and organizations. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level Tasks performed by workers in this sub-major group usually include: formulating and administering policy advice and strategic and financial planning; establishing and directing operational and administrative procedures; implementing, monitoring and evaluating strategies and policies; providing advice to senior managers; directing the development of initiatives for new products, marketing, public relations and advertising campaigns; determining and directing sales activities, product mix and customer service standards; setting prices and credit arrangements; ensuring compliance with relevant legislation, regulations and standards; controlling selection, training and performance of staff; preparing budgets and overseeing financial operations; consulting with the chief executive and with managers of other departments or sections; controlling expenditure and ensuring the efficient use of resources; representing the enterprise or organization in negotiations, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 121 Business Services and Administration Managers 122 Sales, Marketing and Development Managers

Production and specialised services managers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Managers
in scheme: Occupation Taxonomy
comment: Production and specialized services managers plan, direct and coordinate the production of the goods and the provision of the specialized professional and technical services provided by an enterprise or organization, either as the manager of a department or as the general manager of an enterprise or organization that does not have a hierarchy of managers. They are responsible for manufacturing, mining, construction, logistics, information and communications technology operations for large-scale agricultural, forestry and fisheries operations, and for the provision of health, education, social welfare, banking, insurance and other professional and technical services. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning details of activities in terms of output, services provided, quality, quantity, cost, timeliness and labour requirements; setting standards and objectives; controlling the operation of plant and of procedures; assuring quality of the goods produced and services provided; preparing tenders and contract bids; establishing and managing budgets, monitoring costs, and adjusting activities, procedures and resources to minimize costs; overseeing the acquisition and installation of new plant and equipment; coordinating the implementation of health and safety requirements; planning and directing daily operations; overseeing the selection, training and performance of staff; preparing, or arranging for the preparation of, reports, budgets and forecasts; representing the enterprise or organization in negotiations with other agencies, and at conventions, seminars, public hearings and forums. Occupations in this sub-major group are classified into the following minor groups: 131 Production Managers in Agriculture, Forestry and Fisheries 132 Manufacturing, Mining, Construction and Distribution Managers 133 Information and Communica…

Hospitality, retail and other services managers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Managers
in scheme: Occupation Taxonomy
comment: Hospitality, retail and other services managers plan, organize and direct the operations of establishments which provide accommodation, hospitality, retail and other services. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: planning and organizing special functions, sporting, gaming and entertainment activities and the range and mix of products, stock levels and service standards; promoting and selling goods and services; observing liquor, gaming, health and other laws and regulations; developing and reviewing policies, programmes and procedures concerning customer relations and goods and services provided; promoting facilities for conferences, conventions and trade shows to potential customers; organizing the purchase and maintenance of transport vehicles, equipment and fuel, and transporting goods; controlling the selection, training and supervision of staff; ensuring compliance with occupational health and safety regulations. Occupations in this sub-major group are classified into the following minor groups: 141 Hotel and Restaurant Managers 142 Retail and Wholesale Trade Managers 143 Other Services Managers

Professionals
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Professionals increase the existing stock of knowledge; apply scientific or artistic concepts and theories; teach about the foregoing in a systematic manner; or engage in any combination of these activities. Competent performance in most occupations in this major group requires skills at the fourth ISCO skill level. Tasks performed by professionals usually include: conducting analysis and research, and developing concepts, theories and operational methods; advising on or applying existing knowledge related to physical sciences, mathematics, engineering and technology, life sciences, medical and health services, social sciences and humanities; teaching the theory and practice of one or more disciplines at different educational levels; teaching and educating persons with learning difficulties or special needs; providing various business, legal and social services; creating and performing works of art; providing spiritual guidance; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 21 Science and Engineering Professionals 22 Health Professionals 23 Teaching Professionals 24 Business and Administration Professionals 25 Information and Communications Technology Professionals 26 Legal, Social and Cultural Professionals

Science and engineering professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Science and engineering professionals conduct research; improve or develop concepts, theories and operational methods; or apply scientific knowledge relating to fields such as physics, astronomy, meteorology, chemistry, geophysics, geology, biology, ecology, pharmacology, medicine, mathematics, statistics, architecture, engineering, design and technology. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research, enlarging, advising on or applying scientific knowledge obtained through the study of structures and properties of physical matter and phenomena, chemical characteristics and processes of various substances, materials and products, all forms of human, animal and plant life and of mathematical and statistical concepts and methods; advising on, designing and directing construction of buildings, towns and traffic systems, or civil engineering and industrial structures, as well as machines and other equipment; advising on and applying mining methods and ensuring their optimum use; surveying land and sea and making maps; studying and advising on technological aspects of particular materials, products and processes, and on efficiency of production and work organization; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 211 Physical and Earth Science Professionals 212 Mathematicians, Actuaries and Statisticians 213 Life Science Professionals 214 Engineering Professionals (excluding Electrotechnology) 215 Electrotechnology Engineers 216 Architects, Planners, Surveyors and Designers

Health professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Health professionals conduct research,; improve or develop concepts, theories and operational methods; and apply scientific knowledge relating to medicine, nursing, dentistry, veterinary medicine, pharmacy, and promotion of health. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research and obtaining scientific knowledge through the study of human and animal disorders and illnesses and ways of treating them; advising on or applying preventive and curative measures, or promoting health; preparing scientific papers and reports. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 221 Medical Doctors 222 Nursing and Midwifery Professionals 223 Traditional and Complementary Medicine Professionals 224 Paramedical Practitioners 225 Veterinarians 226 Other Health Professionals

Teaching professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Teaching professionals teach the theory and practice of one or more disciplines at different educational levels; conduct research; improve or develop concepts, theories and operational methods pertaining to their particular discipline; and prepare scholarly papers and books. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting classes, courses, or tutorials at a particular educational level for educational and vocational purposes, including private lessons; conducting adult literacy programmes; teaching and educating persons with learning difficulties or special needs; designing and modifying curricula; inspecting and advising on teaching methods and aids; participating in decisions concerning the organization of teaching and related activities at schools and universities; conducting research in particular subjects to improve or develop concepts, theories or operational methods for application in industrial and other fields; preparing scholarly papers and books. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 231 University and Higher Education Teachers 232 Vocational Education Teachers 233 Secondary Education Teachers 234 Primary School and Early Childhood Teachers 235 Other Teaching Professionals

Business and administration professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Business and administration professionals perform analytical, conceptual and practical tasks to provide services in financial matters, human resource development, public relations, marketing and sales in the technical, medical, information and communications technology areas; and conduct reviews of organizational structures, methods and systems as well as quantitative analyses of information affecting investment programmes. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, analysing and interpreting information on the financial viability, cost structures and trading effectiveness of organizations; conducting audits, preparing financial statements and controlling treasury systems for organizations; developing and reviewing financial plans and strategies, executing buy and sell orders, and negotiating the purchase and sale of commodities; developing, implementing and evaluating staff recruitment, training and development programmes; researching, developing and implementing marketing and public relations campaigns; studying and developing methods and policies to improve and promote government and business operations and effectiveness; acquiring and updating knowledge of employers’ and competitors’ goods and services, and of market conditions; assessing customers’ needs and explaining and demonstrating goods and services to them. Occupations in this sub-major group are classified into the following minor group: 241 Finance Professionals 242 Administration Professionals 243 Sales, Marketing and Public Relations Professionals

Information and communications technology professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Information and communications technology professionals conduct research; plan, design, write, test, provide advice and improve information technology systems, hardware, software and related concepts for specific applications; develop associated documentation including principles, policies and procedures; and design, develop, control, maintain and support databases and other information systems to ensure optimal performance and data integrity and security. Tasks performed by workers in this sub-major group usually include: researching information technology use in business functions; identifying areas for improvement and researching the theoretical aspects and operational methods for the use of computers; evaluating, planning and designing hardware or software configurations for specific applications including for Internet, Intranet and multimedia systems; designing, writing, testing and maintaining computer programs; designing and developing database architecture and database management systems; developing and implementing security plans and data administration policy, and administering computer networks and related computing environments; analysing, developing, interpreting and evaluating complex system design and architecture specifications, data models and diagrams in the development, configuration and integration of computer systems. Occupations in this sub-major group are classified into the following minor groups: 251 Software and Applications Developers and Analysts 252 Database and Network Professionals

Legal, social and cultural professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Professionals
in scheme: Occupation Taxonomy
comment: Legal, social and cultural professionals conduct research; improve or develop concepts, theories and operational methods; or apply knowledge relating to the law, storage and retrieval of information and artefacts, psychology, social welfare, politics, economics, history, religion, languages, sociology, other social sciences, and arts and entertainment. Competent performance in most occupations in this sub-major group requires skills at the fourth ISCO skill level. Tasks performed by workers in this sub-major group usually include: conducting research on legal problems; drafting laws and regulations; advising clients on legal cases; pleading and conducting cases in a court of law; presiding over judicial proceedings in a court of law; developing and maintaining library and gallery collections of archives; conducting research, improving or developing concepts, theories and operational methods or applying knowledge relating to the field of social sciences; conceiving, creating and performing in literary and artistic works; interpreting and communicating news, ideas, impressions and facts. Occupations in this sub-major group are classified into the following minor groups: 261 Legal Professionals 262 Librarians, Archivists and Curators 263 Social and Religious Professionals 264 Authors, Journalists and Linguists 265 Creative and Performing Artists

Technicians and associate professionals
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Technicians and associate professionals perform technical and related tasks connected with research and the application of scientific or artistic concepts and operational methods, and government or business regulations. Competent performance in most occupations in this major group requires skills at the third ISCO skill level. Tasks performed by technicians and associate professionals usually include: undertaking and carrying out technical work connected with research and the application of concepts and operational methods in the fields of physical sciences including engineering and technology, life sciences including the medical profession, and social sciences and humanities; initiating and carrying out various technical services related to trade, finance and administration including administration of government laws and regulations, and to social work; providing technical support for the arts and entertainment; participating in sporting activities; executing some religious tasks. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 31 Science and Engineering Associate Professionals 32 Health Associate Professionals 33 Business and Administration Associate Professionals 34 Legal, Social, Cultural and Related Associate Professionals 35 Information and Communications Technicians

Science and engineering associate professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Technicians and associate professionals
in scheme: Occupation Taxonomy
comment: Science and engineering associate professionals perform technical tasks connected with research and operational methods in science and engineering. They supervise and control technical and operational aspects of mining, manufacturing, construction and other engineering operations, and operate technical equipment including aircraft and ships. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: setting up, monitoring and operating instruments and equipment, conducting and monitoring experiments and tests of systems; collecting and testing samples; recording observations and analysing data; preparing, revising and interpreting technical drawings and diagrams; coordinating, supervising, controlling and scheduling the activities of other workers; operating and monitoring switchboards, computerized control systems, and multi-function process control machinery; performing technical functions to ensure safe and efficient movement and operations in ships, aircraft and other equipment. Occupations in this sub-major group are classified into the following minor groups: 311 Physical and Engineering Science Technicians 312 Mining, Manufacturing and Construction Supervisors 313 Process Control Technicians 314 Life Science Technicians and Related Associate Professionals 315 Ship and Aircraft Controllers and Technicians

Health associate professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Technicians and associate professionals
in scheme: Occupation Taxonomy
comment: Health associate professionals perform technical and practical tasks to support diagnosis and treatment of illness, disease, injuries and impairments in humans and animals, and to support implementation of health care, treatment and referral plans usually established by medical, veterinary, nursing and other health professionals. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in the sub-major group usually include: testing and operating medical imaging equipment and administering radiation therapy; performing clinical tests on specimens of bodily fluids and tissues; preparing medications and other pharmaceutical compounds under the guidance of pharmacists; designing, fitting, servicing and repairing medical and dental devices and appliances; providing nursing and personal care and midwifery support services; using herbal and other therapies based on theories, beliefs and experiences originating in specific cultures. Occupations in this sub-major group are classified into the following minor groups: 321 Medical and Pharmaceutical Technicians 322 Nursing and Midwifery Associate Professionals 323 Traditional and Complementary Medicine Associate Professionals 324 Veterinary Technicians and Assistants 325 Other Health Associate Professionals

Business and administration associate professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Technicians and associate professionals
in scheme: Occupation Taxonomy
comment: Business and administration associate professionals perform mostly technical tasks connected with the practical application of knowledge relating to financial accounting and transaction matters, mathematical calculations, human resource development, selling and buying financial instruments, specialized secretarial tasks, and enforcing or applying government rules. Also included are workers who provide business services such as customs clearance, conference planning, job placements, buying and selling real estate or bulk commodities, and serving as agents for performers such as athletes and artists. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include recording and transmitting buy and sell orders for securities, stocks, bonds or other financial instruments and for foreign exchange for future or immediate delivery; submitting credit and loan applications to management with recommendations for approval or rejection; approving or rejecting applications within authorized limits ensuring that credit standards of the institution are respected; maintaining complete records of all financial transactions of an undertaking according to general bookkeeping principles, with guidance from accountants; assisting in planning and performing mathematical, statistical, actuarial, accounting and related calculations; selling and buying financial instruments. Occupations in this sub-major group are classified into the following minor groups: 331 Financial and Mathematical Associate Professionals 332 Sales and Purchasing Agents and Brokers 333 Business Services Agents 334 Administrative and Specialized Secretaries 335 Government Regulatory Associate Professionals

Legal, social, cultural and related associate professionals
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Technicians and associate professionals
in scheme: Occupation Taxonomy
comment: Legal, social, cultural and related associate professionals perform technical tasks connected with the practical application of knowledge relating to legal services, social work, culture, food preparation, sport and religion. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing technical and practical services and support functions in legal processes and investigations, social and community assistance programmes, and religious and cultural activities; participating and adjudicating in sporting events; developing and delivering sports coaching, fitness and recreational programmes; combining creative and technical skills in a variety of artistic, cultural and culinary activities; creating dishes and menus and overseeing the preparation of meals. Occupations in this sub-major group are classified into the following minor groups: 341 Legal, Social and Religious Associate Professionals 342 Sports and Fitness Workers 343 Artistic, Cultural and Culinary Associate Professionals

Information and communications technicians
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Technicians and associate professionals
in scheme: Occupation Taxonomy
comment: Information and communications technicians provide support for the day-to-day running of computer systems, communications systems and networks, and perform technical tasks related to telecommunications, broadcast image and sound as well as other types of telecommunications signals on land, sea or in aircraft. Competent performance in most occupations in this sub-major group requires skills at the third ISCO skill level. Tasks performed by workers in this sub-major group usually include: providing assistance to information and communications systems users; installing new programs and equipment; establishing, operating and maintaining network and other data communications systems; installing, monitoring and supporting Internet and Intranet websites or web server hardware or software; modifying web pages; and performing web server backup and recovery operations; controlling equipment to record sound, edit and mix image and sound recordings; controlling and maintaining transmitting and broadcast systems and satellite systems for radio and television programmes; controlling and maintaining radio communications systems, satellite services and multiplex systems on land, sea or in aircraft; providing technical assistance connected with research and development of computer systems and telecommunications equipment, or testing prototypes; designing and preparing blueprints of circuitry according to the specifications given; providing technical supervision of the manufacture, utilization, maintenance and repair of telecommunications systems. Occupations in this sub-major group are classified into the following minor groups: 351 Information and Communications Technology Operations and User Support Technicians 352 Telecommunications and Broadcasting Technicians

Clerical support workers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Clerical support workers record, organize, store, compute and retrieve information, and perform a number of clerical duties in connection with money-handling operations, travel arrangements, requests for information, and appointments. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by clerical support workers usually include: stenography, typing, and operating word processors and other office machines; entering data into computers; carrying out secretarial duties; recording and computing numerical data; keeping records relating to stocks, production and transport; keeping records relating to passenger and freight transport; carrying out clerical duties in libraries; filing documents; carrying out duties in connection with mail services; preparing and checking material for printing; assisting persons who cannot read or write with correspondence; performing money-handling operations; dealing with travel arrangements; supplying information requested by clients and making appointments; operating a telephone switchboard. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 41 General and Keyboard Clerks 42 Customer Services Clerks 43 Numerical and Material Recording Clerks 44 Other Clerical Support Workers

General and keyboard clerks
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Clerical support workers
in scheme: Occupation Taxonomy
comment: General and keyboard clerks record, organize, store and retrieve information and perform a wide range of clerical and administrative tasks according to established procedures. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording, preparing, sorting, classifying and filing information; sorting, opening and sending mail; preparing reports and correspondence of a routine nature; photocopying and faxing documents; operating personal computers, word processors or typewriters to record, input and process text and data; proofreading and correcting copy; preparing invoices and checking figures. Occupations in this sub-major group are classified into the following minor groups: 411 General Office Clerks 412 Secretaries (general) 413 Keyboard Operators

Customer services clerks
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Clerical support workers
in scheme: Occupation Taxonomy
comment: Customer services clerks deal with clients in connection with money-handling operations, travel arrangements, requests for information, making appointments, operating telephone switchboards, and interviewing for surveys or to complete applications for eligibility for services. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: performing money-handling operations in banks, post offices, betting and gambling establishments, or dealing with travel arrangements; supplying information requested by clients and making appointments; operating telephone switchboards; greeting and receiving visitors; interviewing survey respondents; interviewing applicants for services. Occupations in this sub-major group are classified into the following minor groups: 421 Tellers, Money Collectors and Related Clerks 422 Client Information Workers

Numerical and material recording clerks
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Clerical support workers
in scheme: Occupation Taxonomy
comment: Numerical and material recording clerks obtain, compile and compute accounting, bookkeeping, statistical, financial and other numerical data, and take charge of cash transactions incidental to business matters. Some occupations classified here keep records of goods produced, purchased, stocked and dispatched, and of materials needed at specified production dates, or keep records of operational aspects and coordinate the timing of passenger and freight transport. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: helping with accounting and bookkeeping records and computations; calculating unit production costs; calculating wages and in some cases preparing wage packets and paying wages; taking charge of cash transactions incidental to the business; obtaining, compiling and computing statistical or actuarial data; performing clerical tasks relating to the financial transactions of an insurance establishment, bank or similar establishment; recording produced, stocked, ordered and dispatched goods; recording production materials received, put into stock or issued; computing quantities of the production materials required at specified dates and helping with preparation and checking of production operation schedules; keeping records of operational aspects and coordinating the timing of passenger and freight transport. Occupations in this sub-major group are classified into the following minor groups: 431 Numerical Clerks 432 Material Recording and Transport Clerks

Other clerical support workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Clerical support workers
in scheme: Occupation Taxonomy
comment: Other clerical support workers sort and deliver mail, file documents, prepare information for processing, maintain personnel records, check material for consistency with original source material, assist persons who cannot read or write, and perform various other specialized clerical duties. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: recording information regarding acquisition, issue and return of library books; classifying and filing various documents and other records; maintaining personnel records; sorting, recording and delivering mail from post offices, as well as from or within an enterprise; coding; correcting proofs; performing a range of miscellaneous clerical duties; writing on behalf of persons who are unable to read or write. Occupations in this sub-major group are classified into the following minor group: 441 Other Clerical Support Workers

Service and sales workers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Services and sales workers provide personal and protective services related to travel, housekeeping, catering, personal care, protection against fire and unlawful acts; or demonstrate and sell goods in wholesale or retail shops and similar establishments, as well as at stalls and on markets. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by services and sales workers usually include: organizing and providing services during travel; housekeeping; preparing and serving of food and beverages; caring for children; providing personal and basic health care at homes or in institutions, as well as hairdressing, beauty treatment and companionship; telling fortunes; embalming and arranging funerals; providing security services and protecting individuals and property against fire and unlawful acts; enforcing of law and order; posing as models for advertising, artistic creation and display of goods; selling goods in wholesale or retail establishments, as well as at stalls and on markets; and demonstrating goods to potential customers. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 51 Personal Services Workers 52 Sales Workers 53 Personal Care Workers 54 Protective Services Workers

Personal service workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Service and sales workers
in scheme: Occupation Taxonomy
comment: Personal services workers provide personal services related to travel, housekeeping, catering and hospitality, hairdressing and beauty treatment, animal care grooming and training, companionship and other services of a personal nature. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: organizing and providing services in connection with travel and sightseeing; housekeeping; preparing and serving food and beverages; hairdressing and beauty treatment; telling fortunes; embalming and arranging funerals; grooming, caring for and training animals; teaching people to drive motor vehicles; providing companionship and other personal services. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 511 Travel Attendants, Conductors and Guides 512 Cooks 513 Waiters and Bartenders 514 Hairdressers, Beauticians and Related Workers 515 Building and Housekeeping Supervisors 516 Other Personal Services Workers

Sales workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Service and sales workers
in scheme: Occupation Taxonomy
comment: Sales workers sell and demonstrate goods in wholesale or retail shops, at stalls and markets, door-to-door, via telephone or customer contact centres. They may record and accept payment for goods and services purchased, and may operate small retail outlets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: selling goods in wholesale or retail establishments, at street or market stalls, door-to-door, via telephone or customer contact centres; demonstrating and displaying goods to potential customers; selling and serving food for immediate consumption at counters and in the street; buying or contracting a regular supply of products to be sold; stacking and displaying goods for sale and wrapping or packing goods sold; determining product mix, stock and price levels for goods to be sold; operating cash registers, optical price scanners, computers or other equipment to record and accept payment for the purchase of goods and services. Supervision of other workers may be required in some occupations classified here. Occupations in this sub-major group are classified into the following minor groups: 521 Street and Market Salespersons 522 Shop Salespersons 523 Cashiers and Ticket Clerks 524 Other Sales Workers

Personal care workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Service and sales workers
in scheme: Occupation Taxonomy
comment: Personal care workers provide care, supervision and assistance for children, patients and elderly, convalescent or disabled persons in institutional and residential settings. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assisting with mobility, washing and other personal needs; assisting children individually to learn social skills; supervising and participating in activities that enhance children’s physical, social, emotional and intellectual development; observing and reporting concerns to appropriate health or social service workers. Occupations in this sub-major group are classified into the following minor groups: 531 Child Care Workers and Teachers’ Aides 532 Personal Care Workers in Health Services

Protective services workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Service and sales workers
in scheme: Occupation Taxonomy
comment: Protective services workers protect individuals and property against fire and other hazards, maintain law and order and enforce laws and regulations. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preventing, fighting and extinguishing fires; rescuing people from burning buildings and accident sites and those trapped in dangerous situations; maintaining law and order, enforcing laws and regulations, patrolling public areas and arresting suspected offenders; directing traffic and assuming authority in the event of accidents; watching over and maintaining order among inmates of prisons, reformatories or penitentiaries; patrolling or monitoring premises to guard property against theft and vandalism, controlling access to establishments and maintaining order and enforcing regulations at public events and within establishments. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor group: 541 Protective Services Workers

Skilled agricultural, forestry and fishery workers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Skilled agricultural, forestry and fishery workers grow and harvest field or tree and shrub crops; gather wild fruits and plants; breed, tend or hunt animals; produce a variety of animal husbandry products; cultivate, conserve and exploit forests; breed or catch fish; and cultivate or gather other forms of aquatic life in order to provide food, shelter and income for themselves and their households. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. Tasks performed by skilled agricultural, forestry and fishery workers usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; gathering wild fruits and plants; breeding, raising, tending or hunting animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; cultivating, conserving and exploiting forests; breeding or catching fish; cultivating or gathering other forms of aquatic life; storing and carrying out some basic processing of their produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 61 Market-oriented Skilled Agricultural Workers 62 Market-oriented Skilled Forestry, Fishery and Hunting Workers 63 Subsistence Farmers, Fishers, Hunters and Gatherers

Market-oriented skilled agricultural workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Skilled agricultural, forestry and fishery workers
in scheme: Occupation Taxonomy
comment: Market-oriented skilled agricultural workers plan, organize and perform farming operations to grow and harvest field or tree and shrub crops; and to produce a variety of animals and animal products for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, spraying, fertilizing and harvesting field crops; growing fruit and other tree and shrub crops; growing garden vegetables and horticultural products; raising, breeding and tending animals mainly to obtain meat, milk, hair, fur, skin, or sericultural, apiarian or other products; storing and carrying out some processing of produce; selling their products to purchasers, marketing organizations or at markets. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 611 Market Gardeners and Crop growers 612 Animal Producers 613 Mixed Crop and Animal Producers

Market-oriented skilled forestry, fishery and hunting workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Skilled agricultural, forestry and fishery workers
in scheme: Occupation Taxonomy
comment: Market-oriented skilled forestry, fishery and hunting workers plan, organize and perform operations to cultivate, conserve and exploit natural and plantation forests; breed and raise fish; harvest and catch fish; and hunt and trap animals, for sale or delivery on a regular basis to wholesale buyers, marketing organizations or at markets. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: renting or investing in equipment and machinery and purchasing supplies; planning and undertaking forestry, aquaculture, fishery and hunting operations; maintaining buildings, tanks, machinery and other equipment; delivering or marketing products; supervising and training other workers. Occupations in this sub-major group are classified into the following minor groups: 621 Forestry and Related Workers 622 Fishery Workers, Hunters and Trappers

Subsistence farmers, fishers, hunters and gatherers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Skilled agricultural, forestry and fishery workers
in scheme: Occupation Taxonomy
comment: Subsistence farmers, fishers, hunters and gatherers grow and harvest field or tree and shrub crops, vegetables and fruit; gather wild fruits, medicinal and other plants; tend or hunt animals; catch fish and gather various forms of aquatic life in order to provide food, shelter and, in some cases, a minimum of cash income for themselves and their households. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing the soil; sowing, planting, tending and harvesting field crops; growing vegetables, fruit and other tree and shrub crops; gathering wild fruits, medicinal and other plants; breeding, tending and feeding animals and poultry mainly to obtain meat, eggs, milk, hair, skin or other products; hunting or trapping animals; catching fish and gathering other forms of aquatic life; fetching water and gathering firewood; storing produce for later use and carrying out some processing of produce; building and maintaining houses and other shelters; making tools, clothes and utensils for use by the household; selling or bartering some products at local markets. Occupations in this sub-major group are classified into the following minor groups: 631 Subsistence Crop Farmers 632 Subsistence Livestock Farmers 633 Subsistence Mixed Crop and Livestock Farmers 634 Subsistence Fishers, Hunters, Trappers and Gatherers

Craft and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Craft and related trades workers apply specific technical and practical knowledge and skills to construct and maintain buildings; form metal; erect metal structures; set machine tools or make, fit, maintain and repair machinery, equipment or tools; carry out printing work; and produce or process foodstuffs, textiles, wooden, metal and other articles, including handicraft goods. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of all stages of the production process, the materials and tools used, and the nature and purpose of the final product. Tasks performed by craft and related trades workers usually include: constructing, maintaining and repairing buildings and other structures; casting, welding and shaping metal; installing and erecting heavy metal structures, tackle and related equipment; making machinery, tools, equipment and other metal articles; setting for operators, or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, engines, vehicles, electrical and electronic instruments and other equipment; making precision instruments, jewellery, household and other precious metal articles, pottery, glass and related products; producing handicrafts; executing printing work; producing and processing foodstuffs and various articles made of wood, textiles, leather and related materials. Supervision of other workers may be included. Self-employed craft and related trades workers, who operate their own businesses either independently or with assistance from a small number of others, may also perform a range of tasks associated with management of the business, account and record keeping and client service, although such…

Building and related trades workers, excluding electricians
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Craft and related trades workers
in scheme: Occupation Taxonomy
comment: Building and related trades workers construct, maintain and repair buildings; erect and repair foundations, walls and structures of brick, stone and similar materials; shape and finish stone for building and other purposes. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, the materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: constructing, maintaining and repairing buildings and other structures, using traditional and/or modern building techniques; constructing and repairing foundations, walls and structures of brick, stone and similar materials; breaking quarried stone into slabs or blocks; cutting, shaping and finishing stone for building, ornamental, monumental and other purposes; erecting reinforced concrete frameworks and structures as well as finishing and repairing cement surfaces; cutting, shaping, assembling and maintaining wooden structures and fittings; performing miscellaneous construction and building maintenance tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 711 Building Frame and Related Trades Workers 712 Building Finishers and Related Trades Workers 713 Painters, Building Structure Cleaners and Related Trades Workers

Metal, machinery and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Craft and related trades workers
in scheme: Occupation Taxonomy
comment: Metal, machinery and related trades workers cast, weld, forge and, by other methods, form metal; erect, maintain and repair heavy metal structures; engage in machine-tool setting as well as in fitting, maintaining and repairing machinery including engines and vehicles; or they produce tools and various non-precious metal articles. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product Tasks performed by workers in this sub-major group usually include: making moulds and cores for casting metal; casting, welding and shaping metal; installing, erecting, maintaining and repairing heavy metal structures, tackle and related equipment; forging and forming steel and other non-precious metals to make and repair machinery, tools, equipment and other articles; setting for operators or setting and operating various machine tools; fitting, maintaining and repairing industrial machinery, including engines and vehicles. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 721 Sheet and Structural Metal Workers, Moulders and Welders, and Related Workers 722 Blacksmiths, Toolmakers and Related Trades Workers 723 Machinery Mechanics and Repairers

Handicraft and printing workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Craft and related trades workers
in scheme: Occupation Taxonomy
comment: Handicraft and printing workers combine artistic and manual skills to design, produce, maintain and decorate precision instruments, musical instruments, jewellery and other precious metals, pottery, porcelain and glassware, items made of wood or textile, leather or related materials, and printed products such as books, newspapers and magazines. They apply traditional and/or recently developed techniques to carve, mould, assemble, weave and decorate various articles; to compose and set type prior to printing; to set up and operate printing presses; to bind and finish printed products; and to prepare stencils and operate screen printing equipment. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work may be carried out by hand or involve the use of hand tools and hand-held power tools, and in some cases the set-up and operation of machinery and machine tools. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: making and repairing nautical, meteorological, optical and other precision instruments and equipment; making and repairing musical instruments; making jewellery and precious metalware; making pottery, porcelain ware, ceramics and glassware; painting and decorating various articles; producing handicraft articles in wood or textile, leather and related materials; performing printing or book-binding tasks. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 731 Handicraft Workers 732 Printing Trades Workers

Electrical and electronic trades workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Craft and related trades workers
in scheme: Occupation Taxonomy
comment: Electrical and electronics trades workers install, fit and maintain electrical wiring systems and machinery and other electrical apparatus, electrical transmission and supply lines and cables, and electronic and telecommunications equipment and systems. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: installing, maintaining, fitting and adjusting electrical and electronic wiring systems, machinery and equipment; examining blueprints, wiring diagrams and specifications to determine sequences and methods of operation; inspecting and testing electrical and electronic systems, equipment, cables and machinery to identify hazards, defects and the need for adjustment or repair; installing, maintaining and repairing electrical and telecommunications transmission lines; joining electrical, telecommunications and data cables; maintaining, troubleshooting, fitting, adjusting, testing and repairing electronic equipment such as commercial and office machines, electronic instruments and control systems, computers, and telecommunications and data transmission equipment. Occupations in this sub-major group are classified into the following minor groups: 741 Electrical Equipment Installers and Repairers 742 Electronics and Telecommunications Installers and Repairers

Food processing, wood working, garment and other craft and related trades workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Craft and related trades workers
in scheme: Occupation Taxonomy
comment: Food processing, woodworking, garment and other craft and related trades workers treat and process agricultural and fisheries raw materials into food and other products, and produce and repair goods made of wood, textiles, fur, leather or other materials. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work is carried out by hand and by hand-powered and other tools which are used to reduce the amount of physical effort and time required for specific tasks, as well as to improve the quality of the products. The tasks call for an understanding of the work organization, materials and tools used, and the nature and purpose of the final product. Tasks performed by workers in this sub-major group usually include: treating and processing meat, fish, grain, fruit, vegetables and related materials into food stuffs, and tobacco into tobacco products; tasting and grading food products and beverages; treating and processing natural fibres, skins and hides; making and repairing furniture and other goods made of wood; preparing hides, skins and pelts for further use; making and repairing textiles, garments, hats, shoes and related products. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 751 Food Processing and Related Trades Workers 752 Wood Treaters, Cabinet-makers and Related Trades Workers 753 Garment and Related Trades Workers 754 Other Craft and Related Workers

Plant and machine operators and assemblers
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Plant and machine operators and assemblers operate and monitor industrial and agricultural machinery and equipment on the spot or by remote control; drive and operate trains, motor vehicles and mobile machinery and equipment; or assemble products from component parts according to strict specifications and procedures. Competent performance in most occupations in this major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of industrial and agricultural machinery and equipment, as well as an ability to cope with machine-paced operations and to adapt to technological innovations. Tasks performed by plant and machine operators and assemblers usually include: operating and monitoring mining or other industrial machinery and equipment for processing metal, minerals, glass, ceramics, wood, paper or chemicals; operating and monitoring machinery and equipment used to produce articles made of metal, minerals, chemicals, rubber, plastics, wood, paper, textiles, fur or leather, and which process foodstuffs and related products; driving and operating trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; and assembling products from component parts according to strict specifications and procedures. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 81 Stationary Plant and Machine Operators 82 Assemblers 83 Drivers and Mobile Plant Operators

Stationary plant and machine operators
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Plant and machine operators and assemblers
in scheme: Occupation Taxonomy
comment: Stationary plant and machine operators monitor and operate stationary industrial plant, machinery and equipment, or for which mobility is not an integral part of operation. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. The work mainly calls for experience with and an understanding of the industrial plant, machinery or equipment being operated and monitored. Ability to cope with machine-paced operations and to adapt to innovations in machinery and equipment are often required. Tasks performed by workers in this sub-major group usually include: setting up, operating and monitoring a variety of stationary plant and machinery; detecting malfunctions and taking corrective action; examining outputs for defects and conformity with specifications and adjusting machine settings accordingly; performing maintenance, repairs and cleaning; recording data and maintaining production records. Supervision of other workers may be included. Occupations in this sub-major group are classified into the following minor groups: 811 Mining and Mineral Processing Plant Operators 812 Metal Processing and Finishing Plant Operators 813 Chemical and Photographic Products Plant and Machine Operators 814 Rubber, Plastic and Paper Products Machine Operators 815 Textile, Fur and Leather Products Machine Operators 816 Food and Related Products Machine Operators 817 Wood Processing and Papermaking Plant Operators 818 Other Stationary Plant and Machine Operators

Assemblers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Plant and machine operators and assemblers
in scheme: Occupation Taxonomy
comment: Assemblers assemble prefabricated parts or components to form subassemblies, products and equipment, according to procedures strictly laid down. The products worked on may be moved from one worker to the next along assembly lines. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: assembling components into various types of product and equipment, according to strictly laid down procedures; reviewing work orders, specifications, diagrams and drawings to determine materials needed and assembly instructions; recording production and operational data on specified forms; inspecting and testing completed components and assemblies, wiring installations and circuits; rejecting faulty assemblies and components. Occupations in this sub-major group are classified into the following minor group: 821 Assemblers

Drivers and mobile plant operators
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Plant and machine operators and assemblers
in scheme: Occupation Taxonomy
comment: Drivers and mobile plant operators drive and tend trains and motor vehicles, or drive, operate and monitor industrial and agricultural machinery and equipment, or execute deck duties on board ship and other water-borne craft. Competent performance in most occupations in this sub-major group requires skills at the second ISCO skill level. Tasks performed by workers in this sub-major group usually include: driving and tending trains and motor vehicles; driving, operating and monitoring mobile industrial and agricultural machinery and equipment; carrying out deck duties on board ship and other water-borne craft. Occupations in this sub-major group are classified into the following minor groups: 831 Locomotive Engine Drivers and Related Workers 832 Car, Van and Motorcycle Drivers 833 Heavy Truck and Bus Drivers 834 Mobile Plant Operators 835 Ships’ Deck Crews and Related Workers

Elementary occupations
type: NamedIndividual
type: Concept
type: Occupation
in scheme: Occupation Taxonomy
comment: Elementary occupations involve the performance of simple and routine tasks which may require the use of hand-held tools and considerable physical effort. Most occupations in this major group require skills at the first ISCO skill level. Tasks performed by workers in elementary occupations usually include: cleaning, restocking supplies and performing basic maintenance in apartments, houses, kitchens, hotels, offices and other buildings; washing cars and windows; helping in kitchens and performing simple tasks in food preparation; delivering messages or goods; carrying luggage and handling baggage and freight; stocking vending-machines or reading and emptying meters; collecting and sorting refuse; sweeping streets and similar places; performing various simple farming, fishing, hunting or trapping tasks; performing simple tasks connected with mining, construction and manufacturing including product-sorting; packing and unpacking produce by hand, and filling shelves; providing various street services; pedalling or hand-guiding vehicles to transport passengers and goods; driving animal-drawn vehicles or machinery. Supervision of other workers may be included. Occupations in this major group are classified into the following sub-major groups: 91 Cleaners and Helpers 92 Agricultural, Forestry and Fishery Labourers 93 Labourers in Mining, Construction, Manufacturing and Transport 94 Food Preparation Assistants 95 Street and Related Sales and Services Workers 96 Refuse Workers and Other Elementary Workers

Cleaners and helpers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Cleaners and helpers perform various tasks in private households, hotels, offices, hospitals and other establishments, as well as in aircraft, trains, coaches, trams and similar vehicles, in order to keep the interiors and fixtures clean, and launder and press garments and textiles by hand. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: sweeping or vacuum cleaning; washing and polishing floors, furniture and other objects; taking care of linen and bedmaking; helping with preparation of meals and cleaning in kitchens; washing and cleaning cars and windows; pressing or laundering garments and textiles by hand. Occupations in this sub-major group are classified into the following minor groups: 911 Domestic, Hotel and Office Cleaners and Helpers 912 Vehicle, Window, Laundry and Other Hand Cleaning Workers

Agricultural, forestry and fishery labourers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Agricultural, forestry and fishery labourers perform simple and routine tasks in the production of crops and livestock, cultivation and maintenance of gardens and parks, exploitation and conservation of forests, and conduct of aquaculture and fisheries operations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: digging, raking and shovelling using hand tools; loading, unloading and stacking supplies, produce and other materials; watering, thinning, weeding and tending crops by hand or using hand tools; planting, harvesting, picking and collecting produce by hand; feeding, watering and cleaning animals and keeping their quarters clean; monitoring livestock and reporting on their condition; preparing and operating nets, lines and other fishing tackle and deck equipment; grading, sorting, bunching and packing produce into containers; performing minor repairs on fixtures, buildings, equipment, vessels and fences. Occupations in this sub-major group are classified into the following minor group: 921 Agricultural, Forestry and Fishery Labourers

Labourers in mining, construction, manufacturing and transport
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Labourers in mining, construction, manufacturing and transport perform simple and routine manual tasks in mining, quarrying, civil engineering, building, manufacturing, transport and storage operations, and operate human-powered and animal-drawn vehicles and machinery. Most occupations in this sub-major group require skills at the first ISCO skill level. Task performed by workers in this sub-major group usually include: digging holes and spreading excavated materials, sand, soil and gravel using hand-held tools; sorting, loading, unloading, moving, stacking and storing materials, equipment, products, supplies, baggage and cargo by hand; cleaning machinery, equipment, tools and work sites; packing and unpacking material and products and filling containers and shelves with products by hand; operating human-powered and animal-drawn vehicles and machinery. Occupations in this sub-major group are classified into the following minor groups: 931 Mining and Construction Labourers 932 Manufacturing Labourers 933 Transport and Storage Labourers

Food preparation assistants
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Food preparation assistants prepare and cook to order a small variety of pre-cooked food or beverages, clear tables, clean kitchen areas and wash dishes. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: preparing simple or pre-prepared foods and beverages such as sandwiches, pizzas, fish and chips, salads and coffee; washing, cutting, measuring and mixing foods for cooking; operating cooking equipment such as grills, microwaves and deep-fat fryers; cleaning kitchens, food preparation areas and service areas; cleaning cooking and general utensils used in kitchens and restaurants. Occupations in this sub-major group are classified into the following minor group: 941 Food Preparation Assistants

Street and related sales and service workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Street and related sales and services workers sell goods (excluding food) for immediate consumption, and provide a variety of services on streets and in other public places such as stations. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: buying or making various items for sale; loading and unloading items for sale and transporting them; obtaining the materials necessary to perform services; approaching people on the street to offer goods or services; cleaning and polishing shoes; cleaning and polishing car windows; running errands; assisting car drivers to find a parking place and ensuring that the car is not damaged during the driver’s absence; handing out leaflets and free newspapers; receiving immediate payment. Occupations in this sub-major group are classified into the following minor groups: 951 Street and Related Services Workers 952 Street Vendors (excluding Food)

Refuse workers and other elementary workers
type: NamedIndividual
type: Concept
type: Occupation
broader transitive: Elementary occupations
in scheme: Occupation Taxonomy
comment: Refuse workers and other elementary workers collect, process and recycle garbage from buildings, yards, streets and other public places. They keep streets and other public places clean and tidy, deliver and carry messages and packages and perform odd jobs for private households or establishments. Most occupations in this sub-major group require skills at the first ISCO skill level. Tasks performed by workers in this sub-major group usually include: collecting, loading and unloading garbage; sweeping streets, parks and other public places; chopping firewood; collecting and carrying firewood, water, packages, luggage and messages; beating dust out of carpets and performing other odd-job tasks. Occupations in this sub-major group are classified into the following minor groups: 961 Refuse Workers 962 Other Elementary Workers

Operative Procedure on Upper Extremity
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0186318
comment: Surgical procedure involving an upper extremity.

Surgical Procedure on Lower Extremity
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0187763
comment: Surgical procedure involiving a lower extremity.

Cone Biopsy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0195324
comment: The excision of a cone of tissue, especially of the CERVIX UTERI. [Definition Source: MSH]

Partial Cystectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
comment: The surgical removal of part of bladder.

Amenorrhea due to Pituitary Dysfunction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Amenorrhea
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5546135
comment: The absence of menses in a woman who has achieved reproductive age due to disorder of pituitary gland. [Partial Defintion Source: NCI

Excision of Benign Neoplasm
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
broader transitive: Excision of Neoplasm
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1293110
comment: Surgical removal of bening neoplasm.

Thyroid Gland Excision
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040145
comment: Surgery to remover part or all of the thyroid gland. [Definition Source: NCI]

Caucasian
type: NamedIndividual
type: Concept
type: Group (social concept)
broader transitive: Ethnic Group
in scheme: Group Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0043157
comment: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa. (OMB) [Definition Source: NCI]

Abdominoplasty
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0198542
comment: Surgical removal of excess abdominal skin and fat and tightening of the ABDOMINAL WALL. Abdominoplasty may include LIPECTOMY of INTRA-ABDOMINAL FAT, tightening of the ABDOMINAL MUSCLES, and re-creation of the UMBILICUS. [Definition Source: MSH]

Black African
type: NamedIndividual
type: Concept
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337824
comment: Denotes a person with ancestral origins are in any of the countries of Africa. [Definition Source: NCI]

Autoimmune Pancytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Pancytopenia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0271893
comment: The autoimmune inability of the bone marrow to produce hematopoietic elements. [Definition Source: NCI]

Bell's Palsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cranial Nerve VII Palsy
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376175
comment: A syndrome characterized by the acute onset of unilateral FACIAL PARALYSIS which progresses over a 2-5 day period. Weakness of the orbicularis oculi muscle and resulting incomplete eye closure may be associated with corneal injury. Pain behind the ear often precedes the onset of paralysis. This condition may be associated with HERPESVIRUS 1, HUMAN infection of the facial nerve. (Adams et al., Principles of Neurology, 6th ed, p1376) [Defintion Source: MSH]

Prolapsed Lumbar Intervertebral Disc
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hernia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0281899
comment: Lumbar Hernia [Definition Source: MedDRA]

Operation on Abdominal Region
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0198482
comment: A surgical procedure located in the abdomnial region.

Coronary Artery Bypass Graft
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010055
comment: Surgery performed to bypass partially or completely occluded coronary arteries, thereby increasing the blood supply of the heart. [Definition Source: NCI]

Lumbar Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hernia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0401119
comment: Lumbar Hernia [Definition Source: SNOMEDCT]

Pulmonary Thromboembolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thromboembolism
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0524702
comment: Pulmonary embolism is caused by emboli, which have originated from venous thrombi, travelling to and occluding the arteries of the lung. [PMID:29770793]

Percutaneous Endoscopic Gastrostomy (PEG)
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
comment: The placement of a feeding tube through the abdominal wall into the stomach using an endoscope. [Definition Source: NCI]

Drainage of Bartholin's Abscess
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0403848
comment: Drainage of abscess of Barholin's gland.

Hysterectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020699
comment: A surgical procedure to remove the uterine body (partial hysterectomy) or the uterine body and cervix (total hysterectomy). [Definition source: NCI]

Atopic Dermatitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Eczema
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011615
comment: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema. [Definition Source: MSH]

Cardioversion
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
comment: The conversion of one cardiac rhythm or electrical pattern to another, almost always from an abnormal to a normal one, by pharmacologic means using medications or by electrical cardioversion using a defibrillator. [Definition Source: NCI]

Removal of Acoustic Neuroma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0576748
comment: Surgical removal of acoustic neuroma.

Excision of Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0576763
comment: Surgical removal of basal cell carcinoma.

Neutropenic Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027947
comment: A decrease in the number of NEUTROPHILS found in the blood. [Definition Source: MSH]

Head and Neck Approaches
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
comment: Any approach involiving the head and neck region.

Black (ethnic group)
type: NamedIndividual
type: Concept
type: Group (social concept)
broader transitive: Ethnic Group
in scheme: Group Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005680
comment: A person having origins in the original peoples of sub-Saharan Africa or the Caribbean.

Asian (ethnic group)
type: NamedIndividual
type: Concept
type: Group (social concept)
broader transitive: Ethnic Group
in scheme: Group Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1282531
comment: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, including for example, Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, the Philippine Islands, Thailand, and Vietnam. (OMB) [Definition Source: NCI]

Excision of Neoplasm
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1299802
comment: The surgical removal of a neoplasm.

Ethnic Group
type: NamedIndividual
type: Concept
type: Group (social concept)
in scheme: Group Taxonomy
comment: A group of people with a common cultural heritage that sets them apart from others in a variety of social relationships. [Definition Source: CSP]

Motor Neuron Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Central Nervous System Degenerative Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085084
comment: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089) [Definition Source: MSH]

Cholecystectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008320
comment: Surgical removal of the gallbladder. [Definition Source: NCI]

Surgical Procedure on Thorax
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0524832
comment: Any surgery performed inside the thoracic cavity. [Definition Source: NCI]

Allergic Asthma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Asthma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155877
comment: Allergic Asthma

Hispanic
type: NamedIndividual
type: Concept
type: Group (social concept)
broader transitive: Ethnic Group
in scheme: Group Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0086409
comment: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race. The term, "Spanish origin" can be used in addition to "Hispanic or Latino". (OMB) [Definition Source: NCI]

Excision of Cyst
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997755
comment: Surgical removal of a cyst.

Operative Procedure on Lumbosacral Spinal Structure
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997868
comment: Lumbo-sacral spine surgery

Surgical Procedure on Cervical Spine
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997463
comment: Surgical procedure on the cervical spine.

Operative Procedure on Thoracic Spinal Structure
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1997608
comment: Thoracic spine surgery.

Gastryc Bypass
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017125
comment: Surgical procedure in which the STOMACH is transected high on the body. The resulting small proximal gastric pouch is joined to any parts of the SMALL INTESTINE by an end-to-side SURGICAL ANASTOMOSIS, depending on the amounts of intestinal surface being bypasses. This procedure is used frequently in the treatment of MORBID OBESITY by limiting the size of functional STOMACH, food intake, and food absorption. [Definition Source: MSH]

Insertion of Implantable Intrathecal Access System
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2960489
comment: Surgical insertion of intrathecal access system for drug delivery.

Closed Fracture of Tibia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Tibia Fracture
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0159870
comment: A closed fracture of the tibia.

Emergency Tracheostomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0189343
comment: Surgical formation of an opening into the trachea through the neck, or the opening so created. [Definition Source: MSH]

Procedure on Pelvic Region of Trunk
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3661975
comment: Pelvic surgery.

Excision of dermatofibroma
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3839771
comment: Surgical removal of dermatofibroma.

Intervertebral Disc Prolapse
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hernia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021818
comment: Herniated Disc [Definition Source: MedDRA]

Repair of Bladder
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0194475
comment: Surgical repair of bladder

Appendectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003611
comment: Surgical removal of the vermiform appendix. [Definition Source: NCI]

Pneumonia Caused By SARS-CoV-2
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Pneumonia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5244027
comment: Pneumonia caused by severe acute respiratory syndrome coronavirus 2 [Definition Source: SNOMEDCT]

Transurethral Prostatectomy
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040771
comment: Prostate tissue removal via a cystoscope. [Definition Source: NCI]

Neck Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Head and Neck Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027531
comment: General or unspecified injuries to the neck. It includes injuries to the skin, muscles, and other soft tissues of the neck. [Defintion Source: MSH]

Herpes Simplex Keratitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Herpes Simplex Virus Infection
broader transitive: Keratitis
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019357
comment: A superficial, epithelial Herpesvirus hominis infection of the cornea, characterized by the presence of small vesicles which may break down and coalesce to form dendritic ulcers (KERATITIS, DENDRITIC). (Dictionary of Visual Science, 3d ed) [Defintion Source: MSH]

Gastroplasty
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017193
comment: Surgical procedures involving the STOMACH and sometimes the lower ESOPHAGUS to correct anatomical defects, or to treat MORBID OBESITY by reducing the size of the stomach. There are several subtypes of bariatric gastroplasty, such as vertical banded gastroplasty, silicone ring vertical gastroplasty, and horizontal banded gastroplasty. [Definition Source: MSH]

Alimentary Tract and Metabolism
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653992

Stomatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653755

Drugs for Acid Related Disorders
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653499

Malgradate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Acid Related Disorders
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0065512

Pantoprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Acid Related Disorders
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0081876

Esomeprazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Acid Related Disorders
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0937846

Proglumide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Acid Related Disorders
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033321

Drugs for Functional Gastrointestinal Disorders
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653766

Domperidone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Functional Gastrointestinal Disorders
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013015

Antiemetics and Antinauseants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653765

Bile and Liver Therapy Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654041

Bile Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Bile and Liver Therapy Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654040

Ursodeoxycholic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Bile Therapy
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042105

Liver Therapy, Lipotropics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Bile and Liver Therapy Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653559

Drugs for Bile Therapy and Lipotropics in Combination
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Bile and Liver Therapy Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653658

Drugs for Constipation
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653756

Lactulose
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Constipation
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022957

Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653721

Sulfasalazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036078

Mesalazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antidiarrheals, Intestinal Antiinflammatory/Antiinfective Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0127615

Antiobesity Preparations, excl. Diet Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653760

Digestives, incl. Enzymes
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653759

Drugs Used in Diabetes
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653344

Insulins and Analogues
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs Used in Diabetes
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653579

Insulin Lispro
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Insulins and Analogues
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0293359

Insulin Glargine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Insulins and Analogues
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0907402

Metformin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs Used in Diabetes
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025598

Gliclazide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs Used in Diabetes
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017631

Glimepiride
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs Used in Diabetes
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0061323

Sitagliptin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs Used in Diabetes
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1565750

Vitamins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042890

Colecalciferol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vitamins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008318

Calcifediol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vitamins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006657

Biotin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vitamins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005575

Mineral Supplements
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0556112

Calcium, Combinations with Vitamin D and/or Other Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Mineral Supplements
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653309

Tonics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3543842

Anabolic Agents for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653709

Appetite Stimulants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376447

Other Alimentary Tract and Metabolism
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3542964

Ademetionine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Alimentary Tract and Metabolism
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036002

Blood and Blood Forming Organs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654015

Antithrombotic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Blood and Blood Forming Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1704311

Warfarin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antithrombotic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0043031

Clopidogrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antithrombotic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0070166

Ticlopidine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antithrombotic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040207

Prasugrel
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antithrombotic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1620287

Rivaroxaban
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antithrombotic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1739768

Antihemorrhagics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Blood and Blood Forming Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085824

Antianemic Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Blood and Blood Forming Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653788

Cyanocobalamin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antianemic Preparations
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042845

Blood Substitutes and Perfusion Solutions
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Blood and Blood Forming Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653601

Other Hematological Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Blood and Blood Forming Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540010

Cardiovascular System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540036

Cardiac Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654025

Amiodarone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiac Therapy
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002598

Antihypertensives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003364

Diuretics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012798

Furosemide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Diuretics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016860

Peripheral Vasodilators
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0724804

Nicergoline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Peripheral Vasodilators
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0028008

Vasoprotectives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0304533

Beta Blocking Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001645

Propanolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Beta Blocking Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033497

Atenolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Beta Blocking Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004147

Bisoprolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Beta Blocking Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0053799

Nebivolol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Beta Blocking Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0068475

Atenolol and Other Diuretics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Beta Blocking Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653013

Calcium Channel Blockers
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006684

Amlodipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Calcium Channel Blockers
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0051696

Barnidipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Calcium Channel Blockers
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078703

Lercanidipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Calcium Channel Blockers
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0526399

Verapamil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Calcium Channel Blockers
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042523

Agents Acting on the Renin-Angiotensin System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653735

ACE Inhibitors, Plain
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Agents Acting on the Renin-Angiotensin System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653768

Enalapril
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014025

Ramipril
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0072973

Perindopril and Amlodipine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2931929

Losartan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0126174

Telmisartan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0248719

Olmesartan Medoxomil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: ACE Inhibitors, Plain
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0386393

Lipid Modifying Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Cardiovascular System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653535

Simvastatin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Lipid Modifying Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074554

Atrovastatin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Lipid Modifying Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0286651

Dermatologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011625

Antifungals for Dermatological Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653281

Emollients and Protectives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653752

Preparations for Treatment of Wounds and Ulcers
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653566

Antipruritics, incl. Antihistamines, Anesthetics, etc.
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653761

Antipsoriatics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1874314

Antibiotics and Chemotherapeutics for Dermatological Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653726

Corticosteroids, Dermatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653505

Hydrocortisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Corticosteroids, Dermatological Preparations
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020268

Antispetic and Disinfectants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653284

Medicated Dressings
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0471863

Anti-Acne Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358061

Other Dermatological Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dermatologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653942

Genito Urinary System and Sex Hormones
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653431

Gynecological Antiinfectives and Antiseptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Genito Urinary System and Sex Hormones
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653587

Other Gynecologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Genito Urinary System and Sex Hormones
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653939

Sex Hormones and Modulators of the Genital System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Genito Urinary System and Sex Hormones
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653561

Desogestrel and Ethinylestradiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sex Hormones and Modulators of the Genital System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1112096

Drospirenone and Ethinylestradiol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sex Hormones and Modulators of the Genital System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2604206

Progestogens and Estrogens Systemic Contraceptives, Sequential Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sex Hormones and Modulators of the Genital System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540748

Urologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Genito Urinary System and Sex Hormones
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653764

Oxybutynin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Urologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0069805

Tolterodine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Urologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0388753

Trospium
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Urologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0772089

Sildenafil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Urologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0529793

Tamsulosin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Urologicals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0257343

Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653821

Pituitary and Hypothalamic Hormones and Analogues
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653567

Corticotropin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Pituitary and Hypothalamic Hormones and Analogues
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001655

Tetracosactide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Pituitary and Hypothalamic Hormones and Analogues
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010192

Corticosteroids for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653708

Glucocorticoids, Systemic
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Corticosteroids for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540777

Betamethasone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005308

Dexamethasone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011777

Methylprednisolone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025815

Prednisolone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032950

Prednisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032952

Hydrocortisone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020268

Deflazacort
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Glucocorticoids, Systemic
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0057258

Thyroid Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540775

Levothyroxine Sodium
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Thyroid Therapy
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0079691

Thiamazole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Thyroid Therapy
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025644

Pancreatic Hormones
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030292

Calcium Homeostasis
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653518

Antiinfectives for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653775

Antibacterials for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653727

Amoxicillin and Beta-Lactamase Inhibitor
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antibacterials for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653015

Ceftriaxone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antibacterials for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007561

Antimycotics for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653762

Antimycobacterials
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0360390

Rifampicin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antimycobacterials
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035608

Antivirals for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653777

Aciclovir
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antivirals for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001367

Valaciclovir
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antivirals for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0249458

Immune Sera and Immunoglobulins
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653581

Immunoglobulins, Normal Human, for Intravascular Adm.
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immune Sera and Immunoglobulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652960

Tetanus Immunoglobulin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immune Sera and Immunoglobulins
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4048265

Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinfectives for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042210

Diphtheria Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vaccines
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012551

Hepatitis B, Purified Antigen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vaccines
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652493

Poliomyelitis, Trivalent, Inactivated, Whole Virus
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vaccines
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3652521

Other Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Vaccines
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653947

Antineoplastic and Immunomodulating Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653621

Antineoplastic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic and Immunomodulating Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003392

Cyclophosphamide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010583

Methotrexate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025677

Cladribine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0092801

Mitoxantrone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026259

Alectinib
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3853921

Rituximab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0393022

Trastuzumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0728747

Endocrine Therapy
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic and Immunomodulating Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540795

Tamoxifen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Endocrine Therapy
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039286

Immunostimulants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic and Immunomodulating Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001551

Interferon Beta Natural
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015980

Interferon Beta-1a
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0254119

Interferon Beta-1b
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0244713

Peginterferon Alfa-2b
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0796545

Peginterferon Beta-1a
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3848580

BCG Vaccine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004886

Glatiramer Acetate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunostimulants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0289884

Immunosuppressants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antineoplastic and Immunomodulating Agents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021081

Natalizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1172734

Fingolimod
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1699926

Teriflunomide
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1718383

Alemtuzumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0383429

Ocrelizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1882138

Cladribine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0092801

Siponimod
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3657824

Daclizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0663182

Ustekinumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1608841

Tocilizumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1609165

Secukinumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3179547

Azathioprine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004482

Methotrexate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025677

Dimethyl Fumarate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Immunosuppressants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0058218

Musculo-Skeletal System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653821

Antiinflammatory and Antirheumatic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653623

Indometacin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinflammatory and Antirheumatic Products
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021246

Ketorolac
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinflammatory and Antirheumatic Products
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0073631

Ibuprofen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinflammatory and Antirheumatic Products
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020740

Etoricoxib
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiinflammatory and Antirheumatic Products
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0972314

Topical Products for Joint and Muscular Pain
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653753

Muscle Relaxants
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358430

Botulinum Toxin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Muscle Relaxants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006055

Baclofen
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Muscle Relaxants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004609

Tizanidine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Muscle Relaxants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0146011

Dantrolene
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Muscle Relaxants
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010976

Antigout Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018100

Drugs for Treatment of Bone Diseases
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653497

Denosumab
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Drugs for Treatment of Bone Diseases
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1690432

Other Drugs for Disorders of the Musculo-Skeletal System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Musculo-Skeletal System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653872

Nervous System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3542961

Anesthetics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002932

Analgesics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002771

Codeine, Combinations excl. Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Analgesics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653191

Acetylsalicylic Acid, Combinations excl. Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Analgesics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653192

Paracetamol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Analgesics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000970

Cannabinoids
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Analgesics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006864

Zolmitriptan
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Analgesics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0528166

Antiepileptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003299

Phenobarbital
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031412

Barbexaclone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0105205

Phenytoin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031507

Clonazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009011

Carbamazepine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006949

Oxcarbazepine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0069751

Valproic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042291

Vigabatrin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0048044

Lamotrigine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0064636

Topiramate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0076829

Gabapentin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0060926

Levetiracetam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0377265

Pregabalin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiepileptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0657912

Anti-Parkinson Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003405

Levodopa and Decarboxylase Inhibitor
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Anti-Parkinson Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653004

Amantadine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Anti-Parkinson Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002403

Ropinirole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Anti-Parkinson Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0244821

Pramipexole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Anti-Parkinson Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074710

Cabergoline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Anti-Parkinson Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0107994

Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653516

Zuclopenthixol
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0376160

Olanzapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0171023

Quetiapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0123091

Paliperidone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0753678

Diazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012010

Bromazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006213

Clobazam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0055891

Prazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032910

Alprazolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002333

Etizolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0059862

Hypnotics and Sedatives
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psycholeptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020592

Flurazepam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Hypnotics and Sedatives
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016375

Triazolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Hypnotics and Sedatives
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040879

Brotizolam
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Hypnotics and Sedatives
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0054151

Zolpidem
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Hypnotics and Sedatives
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078839

Melatonin
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Hypnotics and Sedatives
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0025219

Psychoanaleptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653540

Amitriptyline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002600

Fluoxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016365

Citalopram
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008845

Paroxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0070122

Sertraline
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0074393

Escitalopram
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1099456

Trazodone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040805

Mitrazapine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0049506

Venlafaxine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0078569

Reboxetine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0168388

Modafinil
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0066677

Acetylcarnitine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001040

Amitriptyline and Psycholeptics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653016

Rivastigmine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Psychoanaleptics
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0649350

Other Nervous System Drugs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Nervous System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653848

Naltrexone
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027360

Betahistine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005301

Cinnarizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008803

Flunarizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016295

Cinnarizine, Combinations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653100

Riluzole
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0073379

Fampridine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000477

Antiparasitic Products, Insecticides and Repellents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653620

Antiprotozoals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiparasitic Products, Insecticides and Repellents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003416

Hydroxychloroquine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiprotozoals
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020336

Anthelmintics
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiparasitic Products, Insecticides and Repellents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003158

Ectoparasiticides, incl. Scabicides, Insecticides and Repellents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antiparasitic Products, Insecticides and Repellents
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653591

Respiratory System
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0282686

Nasal Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653410

Throat Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653754

Drugs for Obstructive Airway Diseases
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653498

Cough and Cold Preparations
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1511537

Antihistamines for Systemic Use
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653763

Chlorphenamine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antihistamines for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008281

Thiethylperazine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antihistamines for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039865

Cetirizine
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Antihistamines for Systemic Use
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0055147

Other Respiratory System Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Respiratory System
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653833

Sensory Organs
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3654000

Ophthalmologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sensory Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2013096

Otologicals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sensory Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653485

Ophthalmologicals and Otologicals Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Sensory Organs
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653568

Various
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3540763

Allergens
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002092

All Other Therapeutic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653767

Calcium Folinate
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: All Other Therapeutic Products
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0731033

Diagnostic Agents
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358514

General Nutrients
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653491

All Other Non-Therapeutic Products
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653748

Contrast Media
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009924

Diagnostic Radiopharmaceuticals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0360048

Therapeutic Radiopharmaceuticals
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0358509

Surgical Dressings
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Various
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3653515

Two Vessel Coronary Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581375
comment: There was greater than or equal to 50% stenosis (reduction in cross-sectional area) in two coronary arteries (or greater than or equal to 50% stenosis in the left main coronary artery). (ACC) [Definition Source: NCI]

Sign or Symptom
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037088
comment: Objective evidence of disease perceptible to the examining practitioner (sign) and subjective evidence of disease perceived by the patient (symptom). [Definition Source: NCI]

Third Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3639750
comment: Any individual related biologically or legally to another individual and considered two degrees removed from the immediate family as in the case of cousins. [Definition Source: NCI]

Spina Bifida
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Non-Neoplastic Central Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0080178
comment: A congenital neural tube defect in which vertebrae are not fully formed. It results in the protrusion of the spinal cord through the opening of the vertebrae. [Definition Source: NCI]

C9orf72 Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1428691
comment: This gene may play a role in cell death. [Definition Source: NCI]

SQSTM1 Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420393
comment: This gene is involved in signal transduction. [Definition Source: NCI]

Brother
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3830065
comment: A male who shares with his sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]

Sister
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3827310
comment: A female who shares with her sibling the genetic makeup inherited from both of the biological parents. [Definition Source: NCI]

Angioedema
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002994
comment: Rapid swelling of the deep layers of the skin due to transient vascular leakage of serous fluid. [Definition Source: NCI][attribution: NICHD]

Blepharitits
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005741
comment: Inflammation of the eyelids near the eyelashes. [Definition Source: NCI][attribution: NICHD]

Drug Hypersensitivity Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3541994
comment: A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one or more internal organs. [Definition Source: NCI][attribution: NICHD]

Molluscum Contagiosum Virus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026394
comment: A species of enveloped and brick-shaped viruses in the Poxviridae family and Molluscipoxvirus genus. The genome is composed of non-segmented, linear double-stranded DNA. Molluscum contagiosum viruses are found in humans and can cause the disease Molluscum contagiosum. Molluscum contagiosum viruses are transmitted via direct person-to-person contact and contact with infected fomites. [Definition Source: NCI]

Tinea Versicolor
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040262
comment: A skin condition characterized by hypopigmented, pink or tan, confetti-like, discrete and confluent scaly macules distributed on the chest, shoulders and upper back. [Definition Source: NCI]

Ureteral Stenosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0521618
comment: Narrowing of the luminal diameter of one or both ureters due to intrinsic factors. [Definition Source: NCI]

Anosmia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003126
comment: Inability to smell. [Definition Source: NCI]

Ageusia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2364111
comment: Inability to taste. [Definition Source: NCI]

Subdural Hematoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018946
comment: A collection of blood between the dura mater and the brain. [Definition Source: NCI]

Cognitive Impariment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338656
comment: Diminished mental function. [Definition Source: NCI]

Migraine With Aura
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Migraine
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0154723
comment: A migraine disorder characterized by episodes that are preceded by focal neurological symptoms. [Definition Source: NCI]

Post-Herpetic Neuralgia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032768
comment: Pain that occurs after the disappearance of herpes zoster infection lesions. [Definition Source: NCI]

Blepharospasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Head and Neck Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005747
comment: Involuntary twitching of the eyelid. [Definition Source: NCI]

OPTN Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1424774
comment: This gene plays a role in both neuroprotection and Golgi maintenance [Definition Source: NCI]

Dog Bite
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0259797
comment: A wound received from the teeth of a dog. [Definition Source: NCI]

DCTN1 Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1413935
comment: This gene is involved in the modulation of retrograde transport of cytoplasmic organelles and vesicles. [Definition Source: NCI]

Acute Pyelonephritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0520575
comment: Sudden onset pyelonephritis. [Definition Source: NCI][attribution: NICHD]

Eye
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015392
comment: The organ of sight or vision. [Definition Source: NCI]

Head
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018670
comment: The anterior and superior part of a human bearing the mouth, the brain and sensory organs. [Definition Source: NCI]

Limb
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015385
comment: A body region referring to an upper or lower extremity. [Definition Source: NCI]

Bone Marrow
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005953
comment: The tissue occupying the spaces of bone. It consists of blood vessel sinuses and a network of hematopoietic cells which give rise to the red cells, white cells, and megakaryocytes. [Definition Source: NCI]

Brain
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006104
comment: An organ composed of grey and white matter containing billions of neurons that is the center for intelligence and reasoning. It is protected by the bony cranium. [Definition Source: NCI]

Brain Stem
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006121
comment: Three sections, the midbrain, pons and medulla oblongata, that are located at the base of the brain. The brain stem regulates the central nervous system, and is vital as a conduit for motor and sensory innervations. [Definition Source: NCI]

Cerebellum
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007765
comment: The portion of the brain located at the base of the skull that is responsible for balance, equilibrium and movement. [Definition Source: NCI]

Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037925
comment: The elongated, approximately cylindrical part of the central nervous system of vertebrates that lies in the vertebral canal and from which the spinal nerves emerge. [Definition Source: NCI][attribution: On-line Medical Dictionary]

Supratentorial Brain
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522407
comment: The part of the brain that is located superior to the tentorium cerebelli. [Definition Source: NCI]

Abdomen
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0230168
comment: The cavity located between the lungs and pelvis. It contains the lower esophagus, stomach, pancreas, intestines, liver, gallbladder and spleen. [Definition Source: NCI]

Upper Extremity
type: NamedIndividual
type: Concept
type: Anatomic Site
broader transitive: Limb
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1140618
comment: The region of the body that includes the arm, the forearm, and hand. [Definition Source: NCI]

Lower Extremity
type: NamedIndividual
type: Concept
type: Anatomic Site
broader transitive: Limb
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023216
comment: The limb that is composed of the hip, thigh, leg and foot. [Definition Source: NCI]

Pelvis
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030797
comment: The bony, basin-shaped structure formed by the hipbones and the base of the backbone supporting the lower limbs in humans. [Definition Source: NCI]

Thorax
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0817096
comment: The division of the body lying between the neck and the abdomen. [Definition Source: NCI]

Viral Pericarditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0276139
comment: Pericarditis that is caused by an infection with a viral agent. [Definition Source: NCI]

Cervical Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581619
comment: The portion of the spinal cord located in the cervical region. [Definition Source: NCI]

Thoracic Spinal Cord
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581620
comment: The portion of the spinal cord located in the thoracic region. [Definition Source: NCI]

Acquired Hypothyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hypothyroidism
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0700502
comment: Hypothyroidism, the cause of which is not present at birth. [Definition Source: NCI]

Vertebral Column
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037949
comment: A series of bones, muscles, tendons, and other tissues reaching from the base of the skull to the tailbone. The vertebral column forms the axis of the skeleton and encloses as well as protects the spinal cord and the fluid surrounding the spinal cord. [Definition Source: NCI]

Neck
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027530
comment: The region that connects the head to the rest of the body. [Definition Source: NCI]

Anatomic Site
type: NamedIndividual
type: ConceptScheme
comment: Named locations of or within the body. [Definition Source: NCIT] The taxnomy is mainly based on NCIT.

Adverse Drug Reaction
type: NamedIndividual
type: ConceptScheme
has top concept: Adverse Drug Event
comment: Any detrimental or unintended response associated with the use of a medication in humans. [Definition Source: NCIT] The taxonomy is based on OAE.

Dietary Supplement
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242295
comment: Oral preparations containing dietary ingredient(s) intended to supplement the diet. Dietary ingredients include vitamins, minerals, herbs, amino acids, extracts and metabolites. [Definition Source: NCI]
note: Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30.

Plasmapheresis
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
broader transitive: Immunoactive Drugs
in scheme: Therapeutic Procedure Type Taxonomy
comment: A procedure that collects plasma from the peripheral blood while returning the rest to the donor. [Definition Source: NCI]

Head and Neck Surgery
type: NamedIndividual
type: Concept
type: Surgical Procedure Type
broader transitive: Head and Neck Approaches
in scheme: Surgical Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1512343
comment: Any surgery involving a structure in the head and neck region. [Definition Source: NCI]

Herpes Simplex Virus Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019348
comment: An infection that is caused by herpes simplex virus. [Definition Source: NCI]

Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Carcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007117
comment: A carcinoma involving the basal cells. [Definition Source: NCI]

Opioid Use Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4324621
comment: The use of opioids that results in the development of a dependency that adversely affects an individual's life. [Definition Source: NCI]

Pneumococcal Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Pneumonia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155862
comment: Pneumonia that is attributed to the bacteria Streptococcus pneumonia. [Definition Source: NCI]

Gene
type: NamedIndividual
type: ConceptScheme
comment: A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function. [Definition Source: NCIT] The taxonomy is based on NCIT.

COVID-19 Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5203670
comment: An acute infection of the respiratory tract that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Based on currently available information, SARS-CoV-2 is thought to mainly spread from person to person through respiratory droplets. Typically, there is a two- to 14-day incubation period and infected persons can present with no symptoms or mild to severe fever, dry cough, fatigue, and difficulty breathing. Dysgeusia, anosmia, and gastrointestinal and flu-like symptoms have also been reported. Older adults and persons of any age who have serious underlying medical conditions may be of higher risk for severe illness, including secondary infections, respiratory failure, and multi-organ dysfunction. [Definition Source: NCI]

Thoracic Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039980
comment: Trauma to the chest. [Definition Source: NCI]

Non-Invasive Mechanical Ventilation (NIV)
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2349740
comment: A type of mechanical ventilation procedure that uses a non-invasive means, such as a face mask or nasal mask, to deliver oxygenated air into the lungs. [Definition Source: NCI]

Hepatic Toxicity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0235378
comment: Toxicity that impairs or damages the liver. [Definition Source: NCI]

Pharmacologic Substance
type: NamedIndividual
type: ConceptScheme
has top concept: Alimentary Tract and Metabolism
has top concept: Blood and Blood Forming Organs
has top concept: Cardiovascular System
has top concept: Dermatologicals
has top concept: Genito Urinary System and Sex Hormones
has top concept: Systemic Hormonal Preparations, excl. Sex Hormones and Insulins
has top concept: Antiinfectives for Systemic Use
has top concept: Antineoplastic and Immunomodulating Agents
has top concept: Musculo-Skeletal System
has top concept: Nervous System
has top concept: Antiparasitic Products, Insecticides and Repellents
has top concept: Respiratory System
has top concept: Sensory Organs
has top concept: Various
comment: Any natural, endogenously-derived, synthetic or semi-synthetic compound with pharmacologic activity. A pharmacologic substance has one or more specific mechanism of action(s) through which it exerts one or more effect(s) on the human or animal body. They can be used to potentially prevent, diagnose, treat or relieve symptoms of a disease. Formulation specific agents and some combination agents are also classified as pharmacologic substances. [Definition Source: NCIT] The taxonomy is based on ATC.

Second Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1519210
comment: Any relative who is two meioses away from a particular individual in a family; a relative with whom one quarter of an individual's genes is shared (i.e., grandparent, grandchild, uncle, aunt, nephew, niece, half-sibling) (from Genetics Home Reference glossary) [Definition Source: NCI]

Relative
type: NamedIndividual
type: Concept
type: KinshipType
in scheme: Kinship Type Taxonomy
comment: A person related by blood or marriage. [Definition Source: NCIT]

First Degree Relative
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1517194
comment: Any relative who is one meiosis away from a particular individual in a family; a relative with whom one half of an individual's genes is shared (i.e., parent, sibling, offspring) (from Genetics Home Reference glossary) [Definition Source: NCI]

TBK1 Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1336579
comment: This gene plays a role in the immune response and signal transduction. [Definition Source: NCI]

Daughter
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337552
comment: A female human offspring. [Definition Source: NCI]

Father
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015671
comment: A male parent. [Definition Source: NCI]

Mother
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026591
comment: A female parent. [Definition Source: NCI]

Son
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: First Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037683
comment: A male human offspring. [Definition Source: NCI]

Anticonvulsant Agent
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
broader transitive: Drugs for Other Diseases
in scheme: Therapeutic Procedure Type Taxonomy
comment: Medicine to stop, prevent, or control seizures (convulsions). [Definition Source: NCI]

Abdominal Pain
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0000737
comment: Painful sensation in the abdominal region. [Definition Source: NCI]

Bacterial Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Pneumonia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004626
comment: Acute infection of the lung parenchyma caused by bacteria (e.g., Streptococcus pneumoniae, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila). Signs and symptoms include productive cough, fever, chills, shortness of breath, and chest pain. [Definition Source: NCI]

Celiac Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007570
comment: An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [Definition Source: NCI]

Chalazion
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007933
comment: An eyelid cyst caused by the blockage of a meibomian gland. [Definition Source: NCI]

Type 2 Diabetes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Diabetes Mellitus
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011860
comment: A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity. [Definition Source: NCI]

Cranial Nerve VII Palsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015469
comment: Partial or complete paralysis of the facial muscles of one side of a person's face. It is caused by damage to the seventh cranial nerve. It is usually temporary but it may recur. [Definition Source: NCI]

Femur Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015802
comment: A traumatic or pathologic injury to the femur in which the continuity of the femur is broken. [Definition Source: NCI]

Gastritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017152
comment: Inflammation of the stomach. [Definition Source: NCI]

Glaucoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017601
comment: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. [Definition Source: NCI]

Hypothyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thyroid Gland Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020676
comment: Abnormally low levels of thyroid hormone. [Definition Source: NCI][attribution: NICHD]

Keratitis
type: NamedIndividual
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022568
comment: Inflammation of the cornea. [Definition Source: NCI]

Keratoconus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022578
comment: A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances. [Definition Source: NCI]

Progressive Multifocal Leukoencephalopathy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023524
comment: A progressive demyelination within the central nervous system associated with reactivation of a latent JC virus infection. [Definition Source: NCI]

Leukopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0750394
comment: A laboratory test result indicating a decreased number of white blood cells in the peripheral blood. [Definition Source: NCI]

Lymphopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Leukopenia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0853986
comment: An abnormally small number of lymphocytes in the circulating blood. [Definition Source: NCI]

Parkinson's Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Extrapyramidal Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030567
comment: A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression. [Definition Source: NCI]

Retinal Detachment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0035305
comment: An eye emergency condition which may lead to blindness if left untreated. It is characterized by the separation of the inner retina layers from the underlying pigment epithelium. Causes include trauma, advanced diabetes mellitus, high myopia, and choroid tumors. Symptoms include sudden appearance of floaters, sudden light flushes, and blurred vision. [Definition Source: NCI]

Sjogren Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Autoimmune Disease
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1527336
comment: An autoimmune disorder affecting the salivary and lacrimal glands. Morphologically, it is characterized by the presence of lymphocytic and plasmacytic infiltrates which cause destruction of these glands. It results in dry mouth and dry eyes. It may be associated with the presence of other autoimmune disorders, including rheumatoid arthritis and lupus erythematosus. [Definition Source: NCI]

Thyroid Gland Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040128
comment: A non-neoplastic or neoplastic disorder that affects the thyroid gland. Representative examples include hyperthyroidism, hypothyroidism, thyroiditis, follicular adenoma, and carcinoma. [Definition Source: NCI]

Thyroiditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thyroid Gland Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040147
comment: Inflammation of the thyroid gland. This category includes Hashimoto thyroiditis, Riedel thyroiditis, acute thyroiditis, subacute thyroiditis, and radiation-induced thyroiditis. [Definition Source: NCI]

Vitiligo
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042900
comment: Generalized well circumscribed patches of leukoderma that are generally distributed over symmetric body locations and is due to autoimmune destruction of melanocytes. [Definition Source: NCI][attribution: NICHD]

Fever Chills
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085594
comment: Shivering secondary to a febrile process. [Definition Source: NCI]

Acute Cystitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149523
comment: An acute infection of the bladder. It is usually caused by bacteria. Signs and symptoms include increased frequency of urination, pain or burning during urination, fever, cloudy or bloody urine, and suprapubic pain. [Definition Source: NCI]

Alanine Aminotransferase Increased
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0151905
comment: An increase in the level of alanine aminotransferase in the blood. [Definition Source: NCI]

Trigeminal Nerve Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0152177
comment: A non-neoplastic or neoplastic disorder affecting the trigeminal nerve (fifth cranial nerve). [Definition Source: NCI]

Ankle Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0159877
comment: Traumatic or pathological injury to the ankle joint in which the continuity of an ankle bone is broken. Symptoms include pain, swelling, and difficulty moving the affected leg and foot. [Definition Source: NCI]

Interstitial Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Pneumonia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0206061
comment: Inflammation of interstitial lung tissue, usually associated with infection. [Definition Source: NCI]

Acute Respiratory Failure
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0264490
comment: Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock. [Definition Source: NCI]

Obstructive Sleep Apnea Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0520679
comment: A disorder characterized by recurrent episodic disruptions of breathing during sleep. It is caused by the intermittent relaxation of pharyngeal muscles leading to the narrowing or complete blockage of the upper airway. This results in compensatory arousal from sleep to breathe again. An anatomically narrow airway from body habitus or enlarged pharyngeal structures may also predispose to obstruction. Clinical presentation usually includes snoring, daytime sleepiness, difficulty concentrating and fatigue. Clinical course may progress to chronic hypoxemia with cardiovascular and cerebrovascular sequelae. [Definition Source: NCI]

Hashimoto Thyroiditis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thyroiditis
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677607
comment: An autoimmune disorder caused by the production of autoantibodies against thyroid tissue. There is progressive destruction of the thyroid follicles leading to hypothyroidism. [Definition Source: NCI]

Non-Neoplastic Central Nervous System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1335000
comment: Any disorder other than abnormal tissue growth resulting from uncontrolled cell proliferation affecting the nervous system.

Thromboembolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040038
comment: Occlusion of the lumen of a vessel by a thrombus that has migrated from a distal site via the blood stream. [Definition Source: NCI]

Sphincter
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1409894
comment: A circular band of muscle that functions to regulate the size of an orifice in the body. [Definition Source: NCI]

Asthma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Chronic Lung Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004096
comment: A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways. [Definition Source: NCI]

Adenocarcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Carcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001418
comment: A common cancer characterized by the presence of malignant glandular cells. Morphologically, adenocarcinomas are classified according to the growth pattern (e.g., papillary, alveolar) or according to the secreting product (e.g., mucinous, serous). Representative examples of adenocarcinoma are ductal and lobular breast carcinoma, lung adenocarcinoma, renal cell carcinoma, hepatocellular carcinoma (hepatoma), colon adenocarcinoma, and prostate adenocarcinoma. [Definition Source: NCI]

AR Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1367578
comment: This gene plays a role in the transcriptional activation of androgen responsive genes. [Definition Source: NCI]

Alzheimer's Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Dementia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002395
comment: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language. [Definition Source: NCI]

Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002871
comment: A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. [Definition Source: NCI]

Anorexia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
comment: Loss of appetite. [Definition Source: NCI]
comment: https://uts.nlm.nih.gov/uts/umls/concept/C1971624

Anxiety Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Psychiatric Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003469
comment: A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [Definition Source: NCI]

Arrhythmia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003811
comment: Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. [Definition Source: NCI]

Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003864
comment: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. [Definition Source: NCI]

Rheumatoid Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Arthritis
broader transitive: Autoimmune Disease
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003873
comment: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor. [Definition Source: NCI]

Autoimmune Disease
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004364
comment: A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis). [Definition Source: NCI]

Psychiatric Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004936
comment: A disorder characterized by behavioral and/or psychological abnormalities, often accompanied by physical symptoms. The symptoms may cause clinically significant distress or impairment in social and occupational areas of functioning. Representative examples include anxiety disorders, cognitive disorders, mood disorders and schizophrenia. [Definition Source: NCI]

Vulvovaginal Candidiasis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006852
comment: Infection of the vulva and vagina with a fungus of the genus CANDIDA. It is a disease associated with HIV infection. [Definition Source: NCI]

Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Malignant Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007097
comment: A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. [Definition Source: NCI]

Malignant Skin Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Malignant Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007114
comment: A primary or metastatic malignant neoplasm involving the skin. Primary malignant skin neoplasms most often are carcinomas (either basal cell or squamous cell carcinomas) or melanomas. Metastatic malignant neoplasms to the skin include carcinomas and lymphomas. [Definition Source: NCI]

Skin Basal Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Basal Cell Carcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007117
comment: The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas. [Definition Source: NCI]

Skin Basosquamous Cell Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Skin Basal Cell Carcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007118
comment: A basal cell carcinoma which displays squamous differentiation. The neoplastic cells have more abundant cytoplasm with more marked keratinization than typical basal cell carcinomas. It usually has a more aggressive clinical course compared to typical basal cell carcinoma, and it may produce regional or widespread metastases. [Definition Source: NCI]

Cardiovascular Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007222
comment: A non-neoplastic or neoplastic disorder affecting the heart or the vessels (arteries, veins and lymph vessels). Representative examples of non-neoplastic cardiovascular disorders are endocarditis and hypertension. Representative examples of neoplastic cardiovascular disorders are endocardial myxoma and angiosarcoma. [Definition Source: NCI]

Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0010709
comment: A sac-like closed membranous structure that may be empty or contain fluid or amorphous material. [Definition Source: NCI]

Depression
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Mood Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011570
comment: A melancholy feeling of sadness and despair. [Definition Source: NCI]

Diabetes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011849
comment: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. [Definition Source: NCI]

Type 1 Diabtes Mellitus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Autoimmune Disease
broader transitive: Diabetes Mellitus
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011854
comment: A chronic condition characterized by minimal or absent production of insulin by the pancreas. [Definition Source: NCI][attribution: NICHD]

Mumps
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026780
comment: A contagious viral infection caused by the mumps virus. Symptoms include swollen and tender parotid glands, fever, muscle aches and fatigue. Due to vaccination programs, mumps has become a rare disease. [Definition Source: NCI]

Disease or Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0012634
comment: Any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person. The term is often used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function. [Definition Source: NCI]

Eczema
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013595
comment: A form of dermatitis characterized by red, itchy, scaly, or crusty patches that can be chronic or intermittent. [Definition Source: NCI][attribution: NICHD]

Endometriosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014175
comment: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs. [Definition Source: NCI]

Seizure Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014544
comment: A brain disorder characterized by episodes of abnormally increased neuronal discharge resulting in transient episodes of sensory or motor neurological dysfunction, or psychic dysfunction. These episodes may or may not be associated with loss of consciousness or convulsions. [Definition Source: NCI]

Generalized Epilepsy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Seizure Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014548
comment: A chronic condition characterised by recurrent generalised seizures. [Definition Source: NCI]

Fibroma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016045
comment: A non-metastasizing neoplasm arising from the fibrous tissue. It is characterized by the presence of spindle-shaped fibroblasts. [Definition Source: NCI]

Cavernous Hemangioma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018920
comment: A hemangioma characterized by the presence of cavernous vascular spaces. [Definition Source: NCI]

Hepatitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019158
comment: Inflammation of the liver; usually from a viral infection, but sometimes from toxic agents. [Definition Source: NCI]

Hepatitis A Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019159
comment: Acute inflammation of the liver caused by the hepatitis A virus. It is highly contagious and usually contracted through close contact with an infected individual or their feces, contaminated food or water. [Definition Source: NCI]

Langerhans Cell Histiocytosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019621
comment: A neoplastic proliferation of Langerhans cells which contain Birbeck granules by ultrastructural examination. Three major overlapping syndromes are recognized: eosinophilic granuloma, Letterer-Siwe disease, and Hand-Schuller-Christian disease. The clinical course is generally related to the number of organs affected at presentation. (WHO, 2001) [Definition Source: NCI]

Hypersensitivity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020517
comment: An immune response that occurs following exposure to an innocuous antigen, but that does not require the presence of preformed antibodies to the antigen. [Definition Source: NCI]

Hypertension
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020538
comment: Blood pressure that is abnormally high. [Definition Source: NCI]

Hypertensive Crisis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020546
comment: A severe, acute increase in blood pressure that may result in stroke or myocardial ischemia. [Definition Source: NCI]

Hyperthyroidism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thyroid Gland Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020550
comment: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor. [Definition Source: NCI]

Epidermal Inclusion Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cyst
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0014511
comment: The most common type of cutaneous cyst. It results from the proliferation of epidermal cells in a circumscribed space within the dermis. It is usually asymptomatic and presents as a firm, round nodule. [Definition Source: NCI]

Multiple Sclerosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Non-Neoplastic Central Nervous System Disorder
broader transitive: Autoimmune Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026769
comment: A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [Definition Source: NCI]

Fungal Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026946
comment: An infection caused by a fungus. [Definition Source: NCI]

Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0375111
comment: A benign or malignant tissue growth resulting from uncontrolled cell proliferation. Benign neoplastic cells resemble normal cells without exhibiting significant cytologic atypia, while malignant cells exhibit overt signs such as dysplastic features, atypical mitotic figures, necrosis, nuclear pleomorphism, and anaplasia. Representative examples of benign neoplasms include papillomas, cystadenomas, and lipomas; malignant neoplasms include carcinomas, sarcomas, lymphomas, and leukemias. [Definition Source: NCI]

Obesity
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0028754
comment: Having a high amount of body fat (body mass index [BMI] of 30 or more). [Definition Source: NCI]

Osteoporosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0029456
comment: A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss). [Definition Source: NCI]

Pituitary Neuroendocrine Tumor
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032000
comment: A well-differentiated neuroendocrine neoplasm that arises from the adenohypophysial cells of the anterior lobe of the pituitary gland. The tumor can be hormonally functioning or not. It has a low frequency of metastatic spread. When metastatic, the term metastatic pituitary neuroendocrine tumor is endorsed instead of pituitary carcinoma. (WHO) [Definition Source: NCI] It has exact synonim: Pituitary Gland Adenoma.

Pleural Effusion
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032227
comment: Increased amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough, and chest pain. It is usually caused by lung infections, congestive heart failure, pleural and lung tumors, connective tissue disorders, and trauma. [Definition Source: NCI]

Pneumonia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032285
comment: An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. [Definition Source: NCI]

Psoriasis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033860
comment: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp. [Definition Source: NCI][attribution: NICHD]

Finding
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1285578
comment: Clinical, laboratory or molecular evidence, or absence of evidence of disease. [Definition Source: NCI]

Stroke
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Non-Neoplastic Central Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0038454
comment: A sudden loss of neurological function secondary to hemorrhage or ischemia in the brain parenchyma due to a vascular event. [Definition Source: NCI]

Thrombocytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0392386
comment: A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood. [Definition Source: NCI]

Toxoplasmosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040558
comment: A parasitic disease contracted by the ingestion or fetal transmission of toxoplasma gondii. [Definition Source: NCI]

Uterine Corpus Leiomyoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042133
comment: A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [Definition Source: NCI]

Congenital Adrenal Hyperplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001627
comment: A genetic disorder characterized by defects in the synthesis of cortisol and/or aldosterone, resulting in hyperplasia of the adrenal cortical cells. [Definition Source: NCI]

Amyotrophic Lateral Sclerosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Motor Neuron Disease
broader transitive: Central Nervous System Degenerative Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002736
comment: A neurodegenerative disorder characterized by progressive degeneration of the motor neurons of the central nervous system. It results in weakness and atrophy of the muscles which leads to an inability to initiate and control voluntary movements. [Definition Source: NCI]

Hereditary Hemolytic Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Anemia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002881
comment: A congenital hemolytic anemia caused by defects of the erythrocyte membrane, enzyme deficiencies, or hemoglobinopathies. [Definition Source: NCI]

Bipolar Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Mood Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0005586
comment: A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression. [Definition Source: NCI]

Closed Dislocation of Shoulder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Shoulder Dislocation
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0434579
comment: A closed dislocation of the shoulder [Definition Source: NCI]

Common Bile Duct Stone
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0009438
comment: The presence of one or more stones in the common bile duct. They are composed either of cholesterol or, less commonly, calcium salts and bilirubin. [Definition Source: NCI]

Favism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Anemia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015702
comment: A condition associated with glucose-6-phosphate dehydrogenase deficiency, which is characterized by hemolysis. [Definition Source: NCI]

Gastroenteritits
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017160
comment: An inflammatory disorder that affects the upper and lower gastrointestinal tract. Most commonly, this is attributed to viruses; however bacteria, parasites or adverse reactions can also be the culprit. Symptoms include acute diarrhea and vomiting. [Definition Source: NCI]

Head Trauma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Head and Neck Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018674
comment: A traumatic injury to the head. [Definition Source: NCI]

Headache
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018681
comment: Pain in various parts of the head, not confined to the area of distribution of any nerve. [Definition Source: NCI]

Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019270
comment: The protrusion of part of an organ or fibroadipose tissue through an abnormal opening. [Definition Source: NCI]

Palmar Fibromatosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013312
comment: A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males. [Definition Source: NCI] It has exact synonim: Dupuytren Contracture; Palmar Fibromatosis; Dupuytren's Contracture.

Inguinal Hernia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hernia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019294
comment: The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region. [Definition Source: NCI]

Cold Sore
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Herpes Simplex Virus Infection
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019345
comment: A lesion caused by type 1 or type 2 herpes simplex virus, involving the oralfacial region. [Definition Source: NCI]

Infectious Mononucleosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021345
comment: A clinical syndrome of fever, sore throat, fatigue, and lymphadenopathy caused by infection with the Epstein-Barr virus. Subsequent physical findings may include hepatomegaly, palatal petechiae, jaundice, uvular edema, and splenomegaly. [Definition Source: NCI]

Intestinal Pseudo-Obstruction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021847
comment: Ileus of the intestine in which there is no mechanical obstruction. [Definition Source: NCI]

Iridocyclitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022073
comment: Inflammation of the iris and the ciliary body. [Definition Source: NCI]

Essential Hypertension
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Hypertension
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0085580
comment: Hypertension that presents without an identifiable cause. [Definition Source: NCI]

Long QT Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023976
comment: A ventricular arrhythmia characterized by a long QT interval, and accompanied by syncopal episodes sometimes leading to sudden death due to paroxysmal ventricular arrhythmia. This arrhythmia is associated with a prolongation of repolarization following depolarization of the cardiac ventricles. The prolongation of the Q-T interval combined with torsades de pointes manifests as several different forms; some may be acquired or congenital; some may lead to serious arrhythmia and sudden cardiac death. [Definition Source: NCI]

Pancytopenia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030312
comment: A finding of low numbers of red and white blood cells and platelets in the peripheral blood. [Definition Source: NCI]

Penicillin Allergy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Drug Hypersensitivity Syndrome
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0030824
comment: An allergy to Penicillin. [Definition Source: NCI]

Personality Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Psychiatric Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0031212
comment: A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual's culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work. [Definition Source: NCI]

Aspiration Pneumonitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1761609
comment: Inflammation of the lungs due to the inhalation of solid or liquid material. [Definition Source: NCI]

Baker Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cyst
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0032650
comment: Swelling and protrusion of the gastrocnemius-semimembranosus bursa due to an accumulation of synovial fluid. [Definition Source: NCI]

Sarcoidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036202
comment: An idiopathic inflammatory disorder characterized by the formation of non-necrotizing epithelioid granulomas which contain giant cells. It usually affects the lungs, lymph nodes, liver, and skin. Cardiac involvement is also possible. [Definition Source: NCI]

Pulmonary Sarcoidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Sarcoidosis
broader transitive: Chronic Lung Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036205
comment: Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss. [Definition Source: NCI]

Shoulder Dislocation
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037005
comment: A dislocation of the shoulder joint. [Definition Source: NCI]

Sinusitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0037199
comment: An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity. [Definition Source: NCI]

Staphylococcal Infection
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0038160
comment: Infection by Staphylococcus. [Definition Source: NCI]

Syncope
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039070
comment: A spontaneous loss of consciousness caused by insufficient blood supply to the brain. [Definition Source: NCI]

Thalassemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0039730
comment: An inherited blood disorder characterized by a decreased synthesis of one of the polypeptide chains that form hemoglobin. Anemia results from this abnormal hemoglobin formation. [Definition Source: NCI]

Cutaneous Melanoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Malignant Skin Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0151779
comment: A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic nevi. Several histologic variants have been recognized, including superficial spreading melanoma, acral lentiginous melanoma, nodular melanoma, and lentigo maligna melanoma. [Definition Source: NCI]

Vulvovaginitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042998
comment: An inflammatory pathologic process that affects the vulva and the vagina. [Definition Source: NCI]

Acute Myocardial Infarction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0155626
comment: Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations. [Definition Source: NCI]

Closed Fracture of Rib
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0435750
comment: A traumatic break in one of the bones in the rib cage that does not involve a break in the adjacent skin. [Definition Source: NCI]

Tooth Abscess
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0518988
comment: An infectious process that affects a tooth. It is characterized by localized periapical or periodontal collection of pus. It presents with pain and swelling of the gums and/or cheek. [Definition Source: NCI]

Monoclonal Gammopathy
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1136085
comment: An abnormal laboratory test result indicating the presence of monoclonal immunoglobulins in the blood or urine. [Definition Source: NCI]

Head and Neck Finding
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0575141
comment: Symptoms, physical examination results, and/or laboratory test results related to the head and neck. [Definition Source: NCI]

Injury
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3263723
comment: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. [Definition Source: NCI]

Bradycardia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Arrhythmia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0428977
comment: An abnormally slow heart rate. Thresholds for different age, gender, and patient populations exist. [Definition Source: NCI]

Hypercholesterolemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1522133
comment: A laboratory test result indicating an increased amount of cholesterol in the blood. [Definition Source: NCI]

Proteinuria
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0033687
comment: The presence of abnormal amounts of protein in the urine. [Definition Source: NCI]

Vertigo
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0042571
comment: A feeling of movement, a sensation as if the external world were revolving around the patient (objective vertigo) or as if he himself were revolving in space (subjective vertigo). Vertigo is medically distinct from dizziness, lightheadedness, and unsteadiness. [Definition Source: NCI]

Skin Cyst
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cyst
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0241060
comment: A cystic lesion located in the skin. [Definition Source: NCI]

High Grade Cervical Squamous Intraepithelial Neoplasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1512433
comment: A precancerous neoplastic process that affects the cervical squamous epithelium. It is usually associated with human papillomavirus infection. It is classified as cervical squamous intraepithelial neoplasia 2 when there is nuclear atypia in both the upper and lower epithelial layers, mitotic figures are confined to the basal two-thirds of the epithelium, and maturation is present in the upper half of the epithelium. It is classified as cervical squamous intraepithelial neoplasia 3 when there is nuclear atypia and mitotic figures throughout the entire thickness of the epithelium, and maturation is absent or confined to the upper third of the epithelium. [Definition Source: NCI]

Myeloproliferative Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1292778
comment: A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid (i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. (WHO 2008) [Definition Source: NCI]

Colon Adenocarcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Adenocarcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338106
comment: An adenocarcinoma arising from the colon. It is more frequently seen in populations with a Western type diet and in patients with a history of chronic inflammatory bowel disease. Signs and symptoms include intestinal bleeding, anemia, and change in bowel habits. According to the degree of cellular differentiation, colonic adenocarcinomas are divided into well, moderately, and poorly differentiated. Histologic variants include mucinous adenocarcinoma, signet ring cell carcinoma, medullary carcinoma, serrated adenocarcinoma, cribriform comedo-type adenocarcinoma, and micropapillary adenocarcinoma. [Definition Source: NCI]

Dementia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Central Nervous System Degenerative Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0497327
comment: Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders. [Definition Source: NCI]

Central Nervous System Degenerative Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Non-Neoplastic Central Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0270715
comment: A disorder of the central nervous system characterized by gradual and progressive loss of neural tissue and neurologic function. [Definition Source: NCI]

Breast Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Carcinoma
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0678222
comment: A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [Definition Source: NCI]

Symptom
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Sign or Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1457887
comment: Subjective evidence of disease perceived by the patient. [Definition Source: NCI]

Lumbosacral Region
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0024094
comment: The part of the spine in the lower back that consists of the lumbar region and the sacrum. [Definition Source: NCI]

Skin Carcinoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Carcinoma
broader transitive: Malignant Skin Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0699893
comment: A carcinoma that arises from the skin. Representative examples are basal cell carcinoma and squamous cell carcinoma. [Definition Source: NCI]

Deep Vein Thrombosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149871
comment: A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. [Definition Source: NCI][attribution: NICHD]

Atrial Fibrillation
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Arrhythmia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004238
comment: A disorder characterized by an electrocardiographic finding of a supraventricular arrhythmia characterized by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape and timing and are accompanied by an irregular ventricular response. (CDISC) [Definition Source: NCI]

Diabetic Ketoacidosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0011880
comment: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids. [Definition Source: NCI]

Heart Failure
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0018801
comment: Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. [Definition Source: NCI]

Lumbar Puncture Headache
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Headache
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0270697
comment: Headache in erect position, after lumbar puncture; due to lowering of intracranial pressure by leakage of cerebrospinal fluid through the needle tract. [Definition Source: NCI]

Neonatal Hearing Impairment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1709158
comment: An abnormality that affects hearing within the first month after birth. It may or may not result in hearing loss. [Definition Source: NCI]

Pulmonary Embolism
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Cardiovascular Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034065
comment: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung. [Definition Source: NCI]

Transient Ischemic Attack
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Non-Neoplastic Central Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007787
comment: A brief attack (from a few minutes to an hour) of cerebral dysfunction of vascular origin, with no persistent neurological deficit. [Definition Source: NCI]

Atrial Flutter
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Arrhythmia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0004239
comment: A disorder characterized by an electrocardiographic finding of an organized, regular atrial rhythm with atrial rate of 240-340 beats per minute. Multiple P waves typically appear in the inferior leads in a saw tooth-like pattern between the QRS complexes. (CDISC) [Definition Source: NCI]

Sign
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Sign or Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0311392
comment: Objective evidence of disease perceptible to the examining healthcare provider. [Definition Source: NCI]

SOD1 Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420306
comment: This gene plays a role in the detoxification of superoxide radicals in the cytosol. [Definition Source: NCI]

Serum Glutamic Pyruvic Transaminase, CTCAE
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1557189
comment: An enzyme that is normally present in liver and heart cells. SGPT is released into blood when the liver or heart is damaged. The blood SGPT levels are thus elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise SGPT levels. Also called alanine aminotransferase (ALT). [Definition Source: RxList] Common Terminology Criteria for Adverse Events (CTCAE) [Definition Source: U.s. Department of Health and Human Services]

Anorectal Fistula
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149889
comment: A pathologic tract that connects an opening in the anal canal to the perianal skin. In the vast majority of cases there is a history of perianal abscess. [Definition Source: NCI]

Myasthenia Gravis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Autoimmune Nervous System Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0026896
comment: A chronic autoimmune neuromuscular disorder characterized by skeletal muscle weakness. It is caused by the blockage of the acetylcholine receptors at the neuromuscular junction. [Definition Source: NCI]

Psoriatic Arthritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Arthritis
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0003872
comment: Joint inflammation associated with psoriasis. [Definition Source: NCI]

Amenorrhea
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0002453
comment: The absence of menses in a woman who has achieved reproductive age. [Definition Source: NCI]

Alpha-Lipoic Acid
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dietary Supplement
in scheme: Pharmacologic Substance
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0023791
comment: A naturally occurring micronutrient, synthesized in small amounts by plants and animals (including humans), with antioxidant and potential chemopreventive activities. Alpha-lipoic acid acts as a free radical scavenger and assists in repairing oxidative damage and regenerates endogenous antioxidants, including vitamins C and E and glutathione. This agent also promotes glutathione synthesis. In addition, alpha-lipoic acid exerts metal chelating capacities and functions as a cofactor in various mitochondrial enzyme complexes involved in the decarboxylation of alpha-keto acids. [Definition Source: NCI]

Neurofibromatosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0162678
comment: An autosomal dominant hereditary neoplastic syndrome. Two distinct clinicopathological entities are recognized: neurofibromatosis type 1 and neurofibromatosis type 2. Neurofibromatosis type 1 is associated with the presence of cafe-au-lait cutaneous lesions, multiple neurofibromas, malignant peripheral nerve sheath tumors, optic nerve gliomas, and bone lesions. Neurofibromatosis type 2 is associated with the presence of schwannomas, meningiomas, and gliomas. [Definition Source: NCI]

Cervical Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0728985
comment: The set of vertebrae immediately caudal to the skull. [Definition Source: NCI]

Lumbar Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3887615
comment: Those vertebrae between the ribs and the pelvis, L1-L5 in man. [Definition Source: NCI]

Thoracic Spine
type: NamedIndividual
type: Concept
type: Anatomic Site
in scheme: Anatomic Site
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0581269
comment: The vertebrae of the thoracic spine, numbered one through twelve in man. [Definition Source: NCI]

Serositis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036749
comment: Inflammation of a serous membrane. [Definition Source: NCI]

Herpes Zoster
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0019360
comment: A common dermal and neurologic disorder caused by reactivation of the varicella-zoster virus that has remained dormant within dorsal root ganglia, often for decades, after the patient's initial exposure to the virus in the form of varicella (chickenpox). It is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. [Definition Source: NCI]

Grandson
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337573
comment: A male grandchild. [Definition Source: NCI]

Granddaughter
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337561
comment: A female grandchild. [Definition Source: NCI]

Niece
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337578
comment: A daughter of your brother or sister. [Definition Source: NCI]

Nephew
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337579
comment: A son of your brother or sister. [Definition Source: NCI]

Cousin
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337580
comment: A child of your aunt or uncle or their descendents. [Definition Source: NCI]

First Cousin
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Third Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337583
comment: A child of your aunt or uncle. [Definition Source: NCI]

Chronic Atropic Gastritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Gastritis
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0017154
comment: Atrophic gastritis that is persistent and long-standing. [Definition Source: NCI]

Malignant Thyroid Gland Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Thyroid Gland Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007115
comment: A primary or metastatic malignant neoplasm affecting the thyroid gland. [Definition Source: NCI]

Melanocytic Nevus
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0027962
comment: A neoplasm composed of melanocytes that usually appears as a dark spot on the skin. [Definition Source: NCI]

Flu-Like Symptoms
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Symptom
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0392171
comment: Complaints describing a pattern similar to influenza, which may include one or more of the following symptoms: fever, chills, muscle or body aches, cough, sore throat, rhinitis, or fatigue. [Definition Source: NCI]

Renal Colic
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0152169
comment: Paroxysmal and severe flank pain radiating to the inguinal area. It is caused by the passage of a kidney stone through the ureter. [Definition Source: NCI]

Allergic Rhinitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2607914
comment: Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life. [Definition Source: NCI]

Extrapyramidal Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Central Nervous System Degenerative Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015371
comment: A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia. Causes include vascular disorders, degenerative disorders, and antipsychotic drugs. [Definition Source: NCI]

TARDBP Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1420588
comment: This gene is involved in transcription and mRNA splicing. [Definition Source: NCI]

Monoclonal B_Cell Lymphocytosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C2698259
comment: A monoclonal expansion of B-lymphocytes with or without the characteristic immunophenotype of chronic lymphocytic leukemia. It precedes virtually all cases of chronic lymphocytic leukemia/small lymphocytic lymphoma. [Definition Source: NCI]

Dyslipidemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242339
comment: A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides. [Definition Source: NCI]

Iron-Deficiency Anemia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Anemia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0162316
comment: Anemia caused by low iron intake, inefficient iron absorption in the gastrointestinal tract, or chronic blood loss. [Definition Source: NCI]

Brown-Sequard Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0242644
comment: A disorder caused by a spinal injury leading to an incomplete spinal lesion. Patients develop paralysis, ataxia and loss of sensation. Causes include spinal cord tumors, spinal traumas, ischemia, and inflammatory processes affecting the spine. [Definition Source: NCI]

Hereditary Factor XI Deficiency
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0015523
comment: A rare inherited bleeding disorder caused by deficiency of coagulation factor XI. It may be asymptomatic or manifest with bleeding. [Definition Source: NCI]

Frontotemporal Dementia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Dementia
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0338451
comment: A syndrome caused by progressive degeneration of the frontal or temporal lobes of the brain. It is manifested with personality changes and deterioration of the language skills. [Definition Source: NCI]

Ichthyosis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0020757
comment: A group of inherited or acquired skin disorders characterized by a dry, thickened, and scaly skin. The skin changes range from mild to severe. [Definition Source: NCI]

Ann Arbor Stage IV Mantle Cell Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677721
comment: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]

Optic Neuritis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0029134
comment: A disorder characterized by inflammation of the optic nerve. Causes include autoimmune disorders, infections, toxins, drugs, and multiple sclerosis. It may manifest with acute loss of vision and pain. [Definition Source: NCI]

Primary Progressive Aphasia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0282513
comment: A rare neurologic progressive disorder characterized by impairment of the language and speech abilities. [Definition Source: NCI]

Primary Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0677930
comment: A tumor at the original site of origin. [Definition Source: NCI]

Spinal and Bulbar Muscular Atrophy, X-linked 1
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1839259
comment: A rare, slowly progressive degenerative disorder affecting males. It is caused by mutations in the androgen receptor (AR) gene. It is characterized by bulbar and limb muscle weakness and atrophy, and gynecomastia. [Definition Source: NCI]

Ann Arbor Stage IV T-Cell Non-Hodgkin Lymphoma
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0854831
comment: Ann Arbor Classification: Stage IV: Diffuse or disseminated involvement of one or more extralymphatic organs, with or without associated lymph node involvement; or isolated extralymphatic organ involvement in the absence of adjacent regional lymph node involvement, but in conjunction with disease in distant site(s); or any involvement of the liver or bone marrow, lungs (other than by direct extension from another site), or cerebrospinal fluid. [Definition Source: NCI]

Cleft Palate
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008925
comment: A congenital abnormality consisting of a fissure in the midline of the hard and/or soft palate; it is the result of the failure of the two sides of the palate to fuse during embryonic development. [Definition Source: NCI]

Fibromyalgia
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0016053
comment: A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation. [Definition Source: NCI]

Migraine
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0149931
comment: A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity. [Definition Source: NCI]

Bowel Obstruction
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0021843
comment: Blockage of the normal flow of the intestinal contents within the bowel. [Definition Source: NCI]

FUS Gene
type: NamedIndividual
type: Concept
type: Gene
in scheme: Gene
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C1414860
comment: This gene is involved in gene expression, genomic integrity and RNA processing. [Definition Source: NCI]

Mood Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Psychiatric Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0525045
comment: A category of psychiatric disorders which have as their most predominant feature a disturbance in mood. [Definition Source: NCI]

Malignant Colon Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0007102
comment: A primary or metastatic malignant neoplasm that affects the colon. Representative examples include carcinoma, lymphoma, and sarcoma. [Definition Source: NCI]

Gastroesophageal Reflux
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C4317146
comment: The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). [Definition Source: NCI]

Alcohol Dependance
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001973
comment: Physical and psychological dependence on alcohol. [Definition Source: NCI]

Malignant Neoplasm
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Neoplasm
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0006826
comment: A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas, Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [Definition Source: NCI]

Scarlet Fever
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0036285
comment: A streptococcal infection, mainly occurring among children, that is characterized by a red skin rash, sore throat, and fever. [Definition Source: NCI]

Aunt
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272868
comment: A female relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]

Grandfather
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337477
comment: A male relative who is the biological father of either the biological mother or the biological father. [Definition Source: NCI]

Grandmother
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0337476
comment: A female relative who is the biological mother of either the biological mother or the biological father. [Definition Source: NCI]

Maternal Aunt
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Aunt
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272872
comment: A female relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]

Maternal Uncle
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Uncle
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272876
comment: A male relative who is a sibling of the biological mother, and who both share a common ancestor. [Definition Source: NCI]

Paternal Aunt
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Aunt
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272877
comment: A female relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]

Paternal Uncle
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Uncle
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272881
comment: A male relative who is a sibling of the biological father, and who both share a common ancestor. [Definition Source: NCI]

Uncle
type: NamedIndividual
type: Concept
type: KinshipType
broader transitive: Second Degree Relative
in scheme: Kinship Type Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C3272882
comment: A male relative who is a sibling of either of the biological parents, and who share a common ancestor. [Definition Source: NCI]

Chicken Pox
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0008049
comment: A contagious childhood disorder caused by the varicella zoster virus. It is transmitted via respiratory secretions and contact with chickenpox blister contents. It presents with a vesicular skin rash, usually associated with fever, headache, and myalgias. The pruritic fluid-filled vesicles occur 10-21 days after exposure and last for 3-4 days. An additional 3-4 days of malaise follows before the affected individual feels better. An individual is contagious 1-2 days prior to the appearance of the blisters until all blisters are crusted over. Generally, healthy individuals recover without complications. [Definition Source: NCI]

Acute Tonsillitis
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0001361
comment: An acute inflammation of the tonsils caused by viruses or bacteria. Signs and symptoms include fever, enlargement of the tonsils, difficulty swallowing, and enlargement of the regional lymph nodes. [Definition Source: NCI]

Chronic Lung Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0746102
comment: A persistent non-neoplastic disorder of the lungs. Representative examples include: chronic obstructive pulmonary disease, chronic bronchitis, emphysema, pulmonary fibrosis, pneumoconiosis, asbestosis, atelectasis, radiation induced pneumonitis, and radiation fibrosis. [Definition Source: NCI]

Klippel-Feil Syndrome
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Disease or Disorder
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0022738
comment: A rare congenital syndrome characterized by the fusion of the vertebrae in the cervical spine. Patients present with a short neck and restricted mobility of the upper spine. Other signs and symptoms include scoliosis, spina bifida, cleft palate, and rib malformations. [Definition Source: NCI]

Radius Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0034628
comment: Traumatic or pathological injury to the radius bone in which the continuity of the bone is broken. [Definition Source: NCI]

Tibia Fracture
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Injury
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0040185
comment: Traumatic or pathological injury to the tibia in which the continuity of the bone is broken. [Definition Source: NCI]

Autoimmune Nervous System Disorder
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Autoimmune Disease
in scheme: Disease, Disorder or Finding Taxonomy
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0751871
comment: A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis. [Definition Source: NCI]

Adverse Drug Event
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
comment: An adverse event that occurs after a drug administration. [Definition Source: OAE]

Administration of Ineffective Drug
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
broader transitive: Adverse Drug Event
in scheme: Adverse Drug Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0852908
comment: An errored drug administration where a patient is administered with an ineffective drug. [Definition Source: OAE]

Drug Hypersensitivity AE
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
broader transitive: Adverse Drug Event
in scheme: Adverse Drug Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0013182
comment: A hypersensitivity AE that has an outcome of allergic reactions to certain drugs. [Definition Source: OAE]

Drug Intolerance AE
type: NamedIndividual
type: Concept
type: Adverse Drug Reaction
broader transitive: Adverse Drug Event
in scheme: Adverse Drug Event
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C0277585
comment: A drug AE that has an outcome of lower threshold to the normal pharmacologic action of a drug. [Definition Source: OAE]

Institute of Molecular Medicine Joao Lobo Antunes
type: NamedIndividual
type: Clinics and Hospitals
label: Instituto de medicina molecular Joao Lobo Antunes @pt

Nicola Ferro
type: NamedIndividual
type: Person

Giorgio Maria Di Nunzio
type: NamedIndividual
type: Person

Laura Menotti
type: NamedIndividual
type: Person

Guglielmo Faggioli
type: NamedIndividual
type: Person

Stefano Marchesin
type: NamedIndividual
type: Person

Gianmaria Silvello
type: NamedIndividual
type: Person

Behavioral Impairment
type: NamedIndividual
type: Concept
type: Disease, Disorder or Finding
broader transitive: Finding
in scheme: Disease, Disorder or Finding Taxonomy
comment: Diminished psychological function.

Cortisone Therapy for Relapse
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
comment: Therapy based on cortisone used for treating relapses.

Drugs for MS Symptomatic Therapy
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
comment: Symptomatic therapy for Multiple Sclerosis (MS).

Drugs for MS Therapy Side Effects
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
comment: Therapy for managing side effects of MS therapy.

Drugs for Other Diseases
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
comment: Any drugs used to treat other diseases.

Immunoactive Drugs
type: NamedIndividual
type: Concept
type: Therapeutic Procedure Type
in scheme: Therapeutic Procedure Type Taxonomy
comment: Therapy employed to slow the progression of the disease.

Covid-19 Vaccines
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Vaccines
conforms to: https://uts.nlm.nih.gov/uts/umls/concept/C5400806

BG-12
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Other Nervous System Drugs
conforms to: Dimethyl Fumarate

Ecunerv
type: NamedIndividual
type: Concept
type: Pharmacologic Substance
broader transitive: Dietary Supplement
comment: Ecunerv is recommended to help maintain normal functions of the nervous system under abnormal conditions such as neuropathy (due to mechanical, metabolic, toxic, ischemic, optical, alcoholic, diabetic or post-herpetic causes), canalicular syndrome, radiculopathy. B-vitamins (B1, B6 and B12) work in synergy with magnesium and help maintain normal functions of the nervous system. Vitamin E helps protect cells from oxidative stress. [Definition Source: https://www.ecupharma.it/en/ecunerv - visited on November 28th, 2022]
note: Dietary supplements do not have an ATC but they belong to the GMP class 4AA2F30.

Disease, Disorder or Finding Taxonomy
type: NamedIndividual
type: ConceptScheme
has top concept: Disease or Disorder
has top concept: Finding
comment: This taxonomy comprises disease, disorder or findings. The taxonomy is mainly based on NCIT.

Group Taxonomy
type: NamedIndividual
type: ConceptScheme
has top concept: Ethnic Group
comment: This taxonomy describes the different ethinic groups. The taxonomy is based on SNOMED-CT.

Kinship Type Taxonomy
type: NamedIndividual
type: ConceptScheme
has top concept: Relative
comment: This taxonomy describes the different type of relative a person can have. The taxonomy is based on NCIT.

Occupation Taxonomy
type: NamedIndividual
type: ConceptScheme
has top concept: Armed forces occupations
has top concept: Managers
has top concept: Professionals
has top concept: Technicians and associate professionals
has top concept: Clerical support workers
has top concept: Service and sales workers
has top concept: Skilled agricultural, forestry and fishery workers
has top concept: Craft and related trades workers
has top concept: Plant and machine operators and assemblers
has top concept: Elementary occupations
comment: This taxonomy describes the occupation of a person. The taxonomy is based on ECO occupations.

Surgical Procedure Type Taxonomy
type: NamedIndividual
type: ConceptScheme
comment: This taxonomy describes the type of surgical procedures. The taxonomy is based on SNOMED-CT.

Therapeutic Procedure Type Taxonomy
type: NamedIndividual
type: ConceptScheme
comment: This taxonomy describes the type of therapeutic procedures. The taxonomy is manly based on NCIT.

Hospital General Universitario Gregorio Marañón
type: NamedIndividual
type: Clinics and Hospitals

Mondino Foundation
type: NamedIndividual
type: Clinics and Hospitals

University of Padua
type: NamedIndividual
type: Clinics and Hospitals
label: Università degli Studi di Padova @it

University of Turin
type: NamedIndividual
type: Clinics and Hospitals
label: Università degli Studi di Torino @it